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Medina County, TX Commercial Real Estate for Sale

287 results
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Natalia, TX Commercial Opportunity
$918,000
34.00 Acres

Natalia, TX Commercial Opportunity

Fm 463, Natalia, TX 78059

34 acres with road frontage near San Antonio.

  • Prime commercial opportunity with substantial road frontage (940 ft FM 463 & 585 ft CR 5715).
  • Income‑producing agricultural property.
  • Excellent investment potential: hold or develop.
  • Convenient location: 20 minutes from San Antonio.
  • Close proximity to I‑35 (10 minutes).
Updated: Dec 8, 2025
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Natalia, TX Unrestricted Land
$150,000
3.00 Acres

Natalia, TX Unrestricted Land

1140 County Road 6710, Natalia, TX 78059

Three acre property suitable for residential or mixed-use development.

  • Flexible Acreage: Seller willing to sell 3 acres or less, or all 9 acres.
  • Unrestricted Land Use: Located outside city limits with no known restrictions, suitable for residential, multifamily, agricultural, or mixed‑use development.
  • Prime Location: Minutes from San Antonio.
  • Level and Clear Land: Beautiful, leveled, and clear land ready for development.
  • Peaceful Country Living: Enjoy the quiet and peaceful environment.
Updated: Feb 18
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Unrestricted Land in Castroville, TX
$2,700,000
5.08 Acres

Unrestricted Land in Castroville, TX

5.077 acres of unrestricted land west of San Antonio.

3100 Us Highway 90 E, Castroville, TX 78009
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Natalia Horse Ranch on 25+ Acres
$650,900
1,920 SF

Natalia Horse Ranch on 25+ Acres

Exceptional horse ranch blending peace and productivity on 25.83 acres.

18434 Fm 471, Natalia, TX 78059
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Natalia Horse Ranch on 20.5 Acres
$410,000
1,920 SF

Natalia Horse Ranch on 20.5 Acres

Horse ranch on 20.5 acres near Natalia, Texas.

18434A Fm 471, Natalia, TX 78059
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Hondo Industrial/Warehouse Opportunity
$1,500,000
23,050 SF

Hondo Industrial/Warehouse Opportunity

4-acre industrial property with refrigerated warehouse and expansion potential.

568 Carter, Hondo, TX 78861
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Downtown Hondo Commercial Building
$750,000
7,500 SF

Downtown Hondo Commercial Building

Large commercial building in Hondo's central business district.

1602 Avenue M, Hondo, TX 78861
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22 Acres of Texas Land
$365,900
22.01 Acres

22 Acres of Texas Land

Versatile, fenced land ideal for agriculture, recreation, or building.

1249 County Road 772, Natalia, TX 78059
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5 Acres Near Devine, TX
$149,500
5.00 Acres

5 Acres Near Devine, TX

5+ acres of land near Devine, Texas, with minimal restrictions.

County Road 671, Devine, TX 78016
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Land For Sale, Devine, TX
Contact for pricing
3,880 SF

Land For Sale, Devine, TX

Land available in Devine, Texas.

808 Chapa, Devine, TX 78016
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Natalia, TX Land Opportunity
$150,000
2.80 Acres

Natalia, TX Land Opportunity

Land available near San Antonio with owner financing.

19101 Fm 463, Natalia, TX 78059
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Hondo Commercial Property For Sale
$1,500,000
23,050 SF

Hondo Commercial Property For Sale

Versatile industrial property in Hondo, TX, near San Antonio.

Hondo, TX 78861
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Unrestricted Land Near Hondo, Texas
$750,000
96.67 Acres

Unrestricted Land Near Hondo, Texas

96-acre unrestricted land suitable for agricultural, recreational, or residential use.

601 Co Rd 642, Yancey, TX 78886
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Commercial Property on Corner Lot
$850,000
64,904 SF

Commercial Property on Corner Lot

1.49 acre commercial property with office-warehouse.

0000 State Highway 173, Hondo, TX 78861
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16+ Acres in Devine, TX
$385,000
16.95 Acres

16+ Acres in Devine, TX

Land with water wells, meter, pens, and fencing near Devine.

179 Pr, Devine, TX 78016
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Natalia, TX Land For Sale
$400,000
20.00 Acres

Natalia, TX Land For Sale

20 acre agricultural land available in Natalia, Texas.

Natalia, TX 78059
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Sky View Ranch Land
$225,000
10.04 Acres

Sky View Ranch Land

10+ acre lot in Sky View Ranch, Dhanis, Texas.

Utopia Frst, D Hanis, TX 78850
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11 Acres in Devine, Texas
$199,000
11.00 Acres

11 Acres in Devine, Texas

Unrestricted 11-acre property ideal for building or investment.

1079 County Road 6610, Devine, TX 78016
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Hondo, TX Commercial Land & Building
$945,000
10,001 SF

Hondo, TX Commercial Land & Building

7.8-Acre Commercial Property, Excellent Location

1536 Fm 2676, Hondo, TX 78861
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Hondo Commercial Building - Prime Location
$750,000
7,500 SF

Hondo Commercial Building - Prime Location

Large corner lot, high-traffic downtown Hondo.

1602 Avenue M, Hondo, TX 78861
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Hondo Commercial Shop - Prime Location
$380,000
6,192 SF

Hondo Commercial Shop - Prime Location

Spacious Shop, .5-Acre Lot, High Visibility

1905 Avenue R, Hondo, TX 78861
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Historic Hondo Commercial Building
$325,000
2,320 SF

Historic Hondo Commercial Building

Prime Downtown Retail Space, 2320 sq ft

1708 Avenue M, Hondo, TX 78861
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Medina County, TX Commercial Real Estate Investment Opportunities Market Analysis

Explore 105 commercial real estate for sale in Medina County, TX, showcased through 287 active listings on our real estate platform. These investment opportunities span a total of 42,524,709 square feet of properties for sale, with an estimated market value of $36,107,059.

Sale prices for business properties in Medina County, TX start at $149,500, averaging $1,002,973, and reaching up to $3,500,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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