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    Woodruff, SC Commercial Real Estate for Sale

    77 results
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    Partially Renovated Building on Highway
    $275,000
    1.10 Acres

    Partially Renovated Building on Highway

    12117 Highway 221, Woodruff, SC 29388

    2,792 SF building with development potential in thriving Woodruff area.

    • Prime location in the thriving Woodruff growth area with high traffic frontage on Highway 221
    • Significant investment potential with ample room for expansion and customization
    • Partially renovated 2,792 SF building with new HVAC, updated electrical, and new windows
    • Multiple points of ingress/egress, suitable for various uses (childcare, school, office, retail)
    • Ample parking available
    Updated: Sep 24, 2025
    View details
    Main Street Woodruff Commercial Property
    $399,000
    0.26 Acres

    Main Street Woodruff Commercial Property

    577 Main St, Woodruff, SC 29388

    Historic Home, Perfect for Business

    View details

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Prime Moore Restaurant Space
    $359,000
    1,800 SF

    Prime Moore Restaurant Space

    1800 SF Restaurant, $359,000

    6884 Us-221, Moore, SC 29369
    View details
    Industrial Building Near I-26
    $1,595,000
    20,000 SF

    Industrial Building Near I-26

    20,000 sq ft industrial building with convenient highway access.

    6724 Highway 221, Moore, SC 29369
    View details
    59 Acres with Waterfalls
    $950,000
    59.41 Acres

    59 Acres with Waterfalls

    Land with waterfalls, creeks, barns, and mobile home near Greenville.

    1443 Henderson Rd, Gray Court, SC 29645
    View details
    59 Acres in Gray Court
    $950,000
    59.41 Acres

    59 Acres in Gray Court

    Unrestricted 59-acre property with waterfalls and established food plots.

    1443 Henderson Rd, Gray Court, SC 29645
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Land on SC-101
    $3,069,000

    Commercial Land on SC-101

    10.23 acres of commercial land suitable for retail/medical development.

    6520 Highway 101, Woodruff, SC 29388
    View details
    Land Near BMW Battery Plant
    $129,000

    Land Near BMW Battery Plant

    Approximately 1.23 acres of land with versatile use.

    331 W Peachtree St, Woodruff, SC 29388
    View details
    Undeveloped Land with Development Potential
    Contact for pricing

    Undeveloped Land with Development Potential

    Large land parcel with utilities and significant development potential.

    6368 Sc-101, Woodruff, SC
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    Prime Land Near BMW Plant
    $1,600,000

    Prime Land Near BMW Plant

    5.5-acre lot near future BMW plant and medical development.

    6440 Sc-101, Woodruff, SC
    View details

    Explore Off-Market Properties in Woodruff, SC

    Consider similar Off-Market properties in Woodruff, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    341 Toy Ln

    341 Toy Ln

    Multifamily properties • 2,210 SF
    Value Estimation by Request
    341 Toy Ln, Woodruff, SC 29388
    View details
    577 Main St

    577 Main St

    Commercial real estate • 0.26 Acres
    Value Estimation by Request
    577 Main St, Woodruff, SC 29388
    View details
    270 South St

    270 South St

    Churches & religious facilities • 2,625 SF
    Value Estimation by Request
    270 South St, Woodruff, SC 29388
    View details
    Woodruff, SC 29388

    Woodruff, SC 29388

    Commercial real estate • 0.23 Acres
    Value Estimation by Request
    Woodruff, SC 29388
    View details
    475 Cross Anchor Rd

    475 Cross Anchor Rd

    Commercial real estate • 0.36 Acres
    Value Estimation by Request
    475 Cross Anchor Rd, Woodruff, SC 29388
    View details
    601 State Rd

    601 State Rd

    Medical offices • 6,972 SF
    Value Estimation by Request
    601 State Rd, Woodruff, SC 29388
    View details
    5590 Sc-101

    5590 Sc-101

    Refrigerated & Cold Storages • 422,280 SF
    Value Estimation by Request
    5590 Sc-101, Woodruff, SC 29388
    View details
    222 Main St

    222 Main St

    INDUSTRIAL (GENERAL) • 5,400 SF
    Value Estimation by Request
    222 Main St, Woodruff, SC 29388-1852
    View details
    115 Coggins Rd

    115 Coggins Rd

    MILL (FEED, GRAIN, LUMBER, TEXTILE) • 10.46 Acres
    Value Estimation by Request
    115 Coggins Rd, Woodruff, SC 29388-9710
    View details
    217 Ss St

    217 Ss St

    MINI-WAREHOUSE, STORAGE • 1,872 SF
    Value Estimation
    $100,000
    217 Ss St, Woodruff, SC 29388-1835
    View details
    Main St

    Main St

    MINI-WAREHOUSE, STORAGE • 3,120 SF
    Value Estimation by Request
    Main St, Woodruff, SC 29388
    View details
    Georgia Rd

    Georgia Rd

    MINI-WAREHOUSE, STORAGE • 7,560 SF
    Value Estimation
    $425,000
    Georgia Rd, Woodruff, SC 29388
    View details
    850 Riv Rd

    850 Riv Rd

    MILL (FEED, GRAIN, LUMBER, TEXTILE) • 10.35 Acres
    Value Estimation by Request
    850 Riv Rd, Woodruff, SC 29388-8401
    View details
    115 Coggins Rd

    115 Coggins Rd

    MILL (FEED, GRAIN, LUMBER, TEXTILE) • 1,408 SF
    Value Estimation by Request
    115 Coggins Rd, Woodruff, SC 29388-9710
    View details
    2563 Trammel Rd

    2563 Trammel Rd

    MINI-WAREHOUSE, STORAGE • 5,000 SF
    Value Estimation
    $115,000
    2563 Trammel Rd, Woodruff, SC 29388-8416
    View details
    3001 Hwy 417

    3001 Hwy 417

    INDUSTRIAL (GENERAL) • 1,074 SF
    Value Estimation by Request
    3001 Hwy 417, Woodruff, SC 29388-8677
    View details
    1085 Sj Workman Hwy

    1085 Sj Workman Hwy

    INDUSTRIAL (GENERAL) • 600 SF
    Value Estimation by Request
    1085 Sj Workman Hwy, Woodruff, SC 29388-8996
    View details
    348 Wofford St

    348 Wofford St

    MINI-WAREHOUSE, STORAGE • 7,200 SF
    Value Estimation by Request
    348 Wofford St, Woodruff, SC 29388-1754
    View details
    10081 Hwy 221

    10081 Hwy 221

    MINI-WAREHOUSE, STORAGE • 1,970 SF
    Value Estimation by Request
    10081 Hwy 221, Woodruff, SC 29388
    View details
    800 Main St

    800 Main St

    MINI-WAREHOUSE, STORAGE • 3,540 SF
    Value Estimation
    $295,000
    800 Main St, Woodruff, SC 29388-9001
    View details
    4590 Hwy 146

    4590 Hwy 146

    MINI-WAREHOUSE, STORAGE • 31,265 SF
    Value Estimation
    $2,370,000
    4590 Hwy 146, Woodruff, SC 29388-9139
    View details
    340 Woodruff St

    340 Woodruff St

    MINI-WAREHOUSE, STORAGE • 8,000 SF
    Value Estimation
    $170,000
    340 Woodruff St, Woodruff, SC 29388-1540
    View details

    Woodruff, SC Commercial Real Estate Investment Opportunities Market Analysis

    Explore 307 commercial real estate investment opportunities in Woodruff, SC with 77 listings featured on our commercial real estate marketplace. The current inventory includes 60,308,931 square feet of properties with an estimated value of $123,455,378.

    Estimated prices for commercial real estate in Woodruff, SC begin at $34,989, with an average of $523,116 and extend to $5,450,000.

    In Woodruff, SC, current investment values show:

    • Retail properties positioned at $369,841
    • Land measuring $796,254
    • Other commercial real estate assessed at $469,962
    • Individual retail properties calculated at $335,106
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    Browse Commercial real estate for Sale Near Woodruff, SC

    Popular Searches in Woodruff, SC

    Most Searched ZIP Codes in Woodruff, SC

    • 29388
    • 29644

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