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    Pickens, SC Commercial Real Estate for Sale

    21 results
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    Unique Office Building Near Courthouse
    $350,000
    0.16 Acres

    Unique Office Building Near Courthouse

    113 Court St, Pickens, SC 29671

    Commercial office building with two units and distinctive architectural features.

    • Prime commercial location next to the Pickens County Court House.
    • Two rental units provide additional income potential.
    • Unique architectural features: soaring wood ceilings, solid wood beams, brick accents, and a double brick fireplace.
    • Flexible floor plan with spacious meeting and conference rooms, kitchenette, and open work areas.
    • Private brick courtyard provides natural light and an appealing outdoor space.
    Updated: Nov 25, 2025
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    Prime Acreage in Pickens, SC
    $570,000
    1.55 Acres

    Prime Acreage in Pickens, SC

    106 Roberts Dr, Pickens, SC 29671

    Acreage in a rapidly growing area of Pickens County.

    • Prime location in a rapidly growing area of Pickens County.
    • Adjacent to major retailers and businesses like Gentry Place Apartments, O'Reilly Auto Parts, and Wal‑Mart shopping center.
    • Walking distance to national retailers and restaurants including Advance Auto Parts, Tractor Supply, Verizon Wireless and Starbucks.
    • Close proximity to Taco Bell and Zaxby’s.
    • Convenient access to mountains and lakes.
    Updated: Jan 13
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    Prime Land in Pickens, SC
    $1,200,000
    3.24 Acres

    Prime Land in Pickens, SC

    3.24 acres in a rapidly growing area with development potential.

    2663 Gentry Memorial Hwy, Pickens, SC 29671
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    Pickens Office Building - Great Potential
    $300,000
    0.76 Acres

    Pickens Office Building - Great Potential

    Spacious office building, ample parking, city limits.

    837 Pendleton Street Ext, Pickens, SC 29671
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    Pickens Restaurant - Turnkey Opportunity
    $350,000
    1,456 SF

    Pickens Restaurant - Turnkey Opportunity

    Fully equipped restaurant, vacant, ready to operate.

    203 Farrs Bridge Rd, Pickens, SC 29671
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    Downtown Pickens Commercial Gem
    $895,000
    0.68 Acres

    Downtown Pickens Commercial Gem

    Prime location, versatile space, renovation underway.

    509 Lewis St, Pickens, SC 29671
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    Pickens Commercial Lot - Great Potential
    $59,500
    0.75 Acres

    Pickens Commercial Lot - Great Potential

    Level lot, high visibility, multi-use potential.

    000 Moorefield Memorial Hwy, Pickens, SC 29671
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    Pickens Commercial Land Opportunity
    $50,000
    1.00 Acre

    Pickens Commercial Land Opportunity

    Acre lot, prime location, $50,000

    4000 Moorefield Memorial Hwy, Pickens, SC 29671
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    Pickens Textile Mill Redevelopment
    $3,600,000
    4,000 SF

    Pickens Textile Mill Redevelopment

    Historic Industrial Site, Huge Potential

    203 Woodrow St, Pickens, SC 29671
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    Prime Pickens County Office Building
    $350,000
    0.16 Acres

    Prime Pickens County Office Building

    Historic Charm, Dual-Income Potential

    113 Court St, Pickens, SC 29671
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    Highway 11 Land Parcel
    Contact for pricing

    Highway 11 Land Parcel

    10.12-acre parcel off Highway 11 in Pickens, SC.

    622 White Crest Way, Pickens, SC 29671
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    Pickens SC Retail Development Site
    $650,000
    2.00 Acres

    Pickens SC Retail Development Site

    High-traffic retail land, two parcels.

    311 Ann St, Pickens, SC 29671
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    Prime Land Near Downtown Pickens
    Contact for pricing

    Prime Land Near Downtown Pickens

    14.87 AC land for sale near downtown Pickens, SC.

    172 Looper Ln, Pickens, SC 29671
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    Prime Land Near Walmart
    Contact for pricing

    Prime Land Near Walmart

    13.35 acre commercial land for sale near downtown Pickens.

    Gentry Memorial Hwy, Pickens, SC 29671
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    Aunt Sue's Restaurant & Land
    $2,800,000

    Aunt Sue's Restaurant & Land

    Established Restaurant, 7+ Acres

    107 Country Creek Dr, Pickens, SC 29671
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    Commercial Land at Signalized Intersection
    Contact for pricing

    Commercial Land at Signalized Intersection

    Land with frontage, utilities, and high traffic for retail.

    311 Ann St, Pickens, SC 29671
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    Prime Land Parcel For Sale
    $600,000

    Prime Land Parcel For Sale

    2.11 AC land parcel with high traffic volume.

    Ann St, Pickens, SC 29671
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    Gentry Hwy Retail Portfolio
    Contact for pricing
    14.00 Acres

    Gentry Hwy Retail Portfolio

    Pickens, SC: 14 acres, 30K+ SF

    2914-2932 Gentry Memorial Hwy, Pickens, SC 29671
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    Established Restaurant in Pickens, SC
    Contact for pricing
    3,610 SF

    Established Restaurant in Pickens, SC

    3,607 SF restaurant on 0.42 acres with ample parking.

    107 S Catherine St, Pickens, SC 29671
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    Prime Commercial Land Available
    Contact for pricing

    Prime Commercial Land Available

    Two one-acre parcels with high traffic and retail potential.

    319 Ann St, Pickens, SC 29671
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    Based on your search, we've compiled Potential Opportunities for your consideration. Besides 21 Active Listings in Pickens, SC

    Pickens, SC Commercial Real Estate Investment Opportunities Market Analysis

    Explore 21 commercial real estate for sale in Pickens, SC, showcased through 21 active listings on our real estate platform. These investment opportunities span a total of 1,532,223 square feet of properties for sale, with an estimated market value of $8,374,500.

    Sale prices for business properties in Pickens, SC start at $50,000, averaging $761,318, and reaching up to $3,600,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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