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    Seneca, MO Commercial Real Estate for Sale

    7 results
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    Turnkey Brewery and Restaurant Space
    $265,000
    6,593 SF

    Turnkey Brewery and Restaurant Space

    1107 Cherokee Ave, Seneca, MO 64865

    Fully equipped brewery and restaurant in historic downtown Seneca, MO.

    • Turnkey brewery and restaurant: Fully built out and equipped, ready for immediate operation.
    • Complete commercial brewing system: Includes an SS Brewtech 304 system, walk‑in coolers/freezers, and 13‑tap dispenser.
    • Multiple income streams: Features a restaurant, private event rooms, gaming area, cigar lounge, slot machines with profit share, and karaoke stage.
    • Prime location: Situated in a historic building in downtown Seneca, attracting regional traffic, including from Indigo Sky Casino.
    • Operational continuity: Most furnishings, equipment, and house recipes convey; existing staff open to staying on.
    Updated: Jan 6
    View details
    Seneca Commercial Property for Sale
    $169,900
    1,737 SF

    Seneca Commercial Property for Sale

    1418 Cherokee Ave, Seneca, MO 64865

    Commercial property in Seneca, Missouri, suitable for various business ventures.

    • High‑visibility corner lot location directly in front of the Seneca Fire Department.
    • Commercial zoning suitable for a business (currently a tattoo shop) or residential use.
    • Carport and off‑street parking available.
    • Convenient access to nearby restaurants and grocery stores.
    • Features a wonderful front porch.
    Updated: Dec 22, 2025
    View details
    Profitable Seneca Car Wash
    $135,000
    2,112 SF

    Profitable Seneca Car Wash

    Five-bay car wash, prime location. High returns!

    1406 Frisco St, Seneca, MO 64865
    View details
    7080 Highway 43, Seneca, MO 64865
    $106,000
    2,257 SF

    7080 Highway 43, Seneca, MO 64865

    Commercial real estate • 2,257 SF

    7080 Highway 43, Seneca, MO 64865
    View details
    Seneca Main Street Commercial Building
    $67,500
    0.09 Acres

    Seneca Main Street Commercial Building

    Prime Seneca Location, Investment Opportunity

    1117 Cherokee Ave, Seneca, MO 64865
    View details
    Seneca Restaurant/Bar Opportunity
    $149,960
    0.09 Acres

    Seneca Restaurant/Bar Opportunity

    Turnkey Restaurant, Great Location!

    Cherokee Ave, Seneca, MO 64865
    View details
    Downtown Seneca Retail Opportunity
    $79,900
    0.07 Acres

    Downtown Seneca Retail Opportunity

    High-visibility corner lot, prime location.

    1320 Cherokee Ave, Seneca, MO 64865
    View details
    Based on your search, we've compiled 152 Potential Opportunities for your consideration. Besides 7 Active listings in Seneca, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 140 Off-Market properties to explore as potential leads, plus 1 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Unrestricted Land in Quapaw, OK
    $34,900
    2.00 Acres

    Unrestricted Land in Quapaw, OK

    Two acres of unrestricted land suitable for residential or recreational use.

    Tbd 660 Rd, Quapaw, OK 74363
    View details
    Land Near Downstream Casino
    $499,000
    3.00 Acres

    Land Near Downstream Casino

    3-acre property near Downstream Casino, suitable for various developments.

    Quapaw, OK 74363
    View details
    Neosho Commercial Building - Great Potential
    $499,900
    6,250 SF

    Neosho Commercial Building - Great Potential

    Spacious Commercial Building, 2 Acres, Excellent Location

    Iris Rd, Neosho, MO 64850
    View details
    Neosho Industrial Property - Great Location
    $499,900
    6,250 SF

    Neosho Industrial Property - Great Location

    Spacious Industrial Building, 2.78 Acres

    000 Iris Rd, Neosho, MO 64850
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Seneca, MO Land For Sale
    $315,000
    45.00 Acres

    Seneca, MO Land For Sale

    45 acres of land suitable for commercial or residential development.

    Highway 60, Seneca, MO 64865
    View details

    Explore Off-Market Properties in Seneca, MO

    Consider similar Off-Market properties in Seneca, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    7080 Highway 43

    7080 Highway 43

    Commercial real estate • 2,257 SF
    Value Estimation by Request
    7080 Highway 43, Seneca, MO 64865
    View details
    Cherokee Ave

    Cherokee Ave

    Commercial real estate • 0.09 Acres
    Value Estimation by Request
    Cherokee Ave, Seneca, MO 64865
    View details
    Seneca, MO 64865

    Seneca, MO 64865

    MANUFACTURING (LIGHT) • 5,463 SF
    Value Estimation
    $740,000
    Seneca, MO 64865
    View details
    318 1st St

    318 1st St

    WAREHOUSE, STORAGE • 2,350 SF
    Value Estimation by Request
    318 1st St, Seneca, MO 64865-9480
    View details
    Seneca, MO 64865

    Seneca, MO 64865

    WAREHOUSE, STORAGE • 1,792 SF
    Value Estimation
    $445,000
    Seneca, MO 64865
    View details
    1118 Cherokee Ave

    1118 Cherokee Ave

    WAREHOUSE, STORAGE • 1,187 SF
    Value Estimation by Request
    1118 Cherokee Ave, Seneca, MO 64865-9207
    View details
    Seneca, MO 64865

    Seneca, MO 64865

    MANUFACTURING (LIGHT) • 22,010 SF
    Value Estimation
    $640,000
    Seneca, MO 64865
    View details
    Seneca, MO 64865

    Seneca, MO 64865

    MINI-WAREHOUSE, STORAGE • 4,000 SF
    Value Estimation by Request
    Seneca, MO 64865
    View details
    Seneca, MO 64865

    Seneca, MO 64865

    MINI-WAREHOUSE, STORAGE • 4,200 SF
    Value Estimation by Request
    Seneca, MO 64865
    View details
    Seneca, MO 64865

    Seneca, MO 64865

    MANUFACTURING (LIGHT) • 20,297 SF
    Value Estimation
    $680,000
    Seneca, MO 64865
    View details
    Seneca, MO 64865

    Seneca, MO 64865

    MINI-WAREHOUSE, STORAGE • 3,180 SF
    Value Estimation
    $455,000
    Seneca, MO 64865
    View details
    Seneca, MO 64865

    Seneca, MO 64865

    OFFICE BUILDING • 960 SF
    Value Estimation
    $355,000
    Seneca, MO 64865
    View details
    Seneca, MO 64865

    Seneca, MO 64865

    COMMERCIAL (GENERAL) • 7,182 SF
    Value Estimation
    $520,000
    Seneca, MO 64865
    View details
    Seneca, MO 64865

    Seneca, MO 64865

    OFFICE BUILDING • 8,531 SF
    Value Estimation by Request
    Seneca, MO 64865
    View details
    Seneca, MO 64865

    Seneca, MO 64865

    MEDICAL BUILDING • 752 SF
    Value Estimation by Request
    Seneca, MO 64865
    View details
    Seneca, MO 64865

    Seneca, MO 64865

    COMMERCIAL (GENERAL) • 2.80 Acres
    Value Estimation by Request
    Seneca, MO 64865
    View details
    1208 Cherokee Ave

    1208 Cherokee Ave

    RETAIL STORES (PERSONAL SERVICES) • 722 SF
    Value Estimation by Request
    1208 Cherokee Ave, Seneca, MO 64865-9208
    View details

    Seneca, MO Commercial Real Estate Investment Opportunities Market Analysis

    Explore 135 commercial real estate investment opportunities in Seneca, MO with 7 listings featured on our commercial real estate marketplace. The current inventory includes 53,712,092 square feet of properties with an estimated value of $15,164,260.

    Estimated prices for commercial real estate in Seneca, MO begin at $67,500, with an average of $286,118 and extend to $595,000.

    In Seneca, MO, current investment values show:

    • Retail properties positioned at $282,175
    • Investment properties measuring $242,083
    • Live-work space assessed at $242,083
    • Mixed-use properties calculated at $242,083
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    Browse Commercial real estate for Sale Near Seneca, MO

    Popular Searches in Seneca, MO

    Most Searched ZIP Codes in Seneca, MO

    • 64865

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