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Neosho, MO Commercial Real Estate for Sale

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46 results
Versatile Commercial Live/Work Property
$185,000
2,500 SF

Versatile Commercial Live/Work Property

9741 Gateway Drive, Neosho, MO 64850

Live/work property with insulated shop near Neosho and I-49.

  • 40x60 insulated red‑iron shop with ~25 ft peak ceilings and concrete floor suitable for trucks, trailers, and equipment.
  • Located minutes from Neosho and I‑49, offering convenient access and visibility.
  • Versatile live/work property on approximately 1 acre with room for parking equipment or vehicles.
  • Updated shop with new lighting, electrical improvements, and fresh paint.
  • Mobile home structure included, suitable for office, storage, or living space.
Updated: Mar 13
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High-Visibility Commercial Building with Drive-Thru
$1,095,000
4,814 SF

High-Visibility Commercial Building with Drive-Thru

925 & 929 S Neosho Boulevard, Neosho, MO 64850

Commercial building with drive-thru on 1.17 acres in Neosho.

  • High‑visibility location on S Neosho Boulevard with 5,000‑10,000 average daily traffic.
  • Benefit from the drive‑thru capability.
  • Flexible 4,814 sq ft interior layout with multiple entrances/exits and commercial kitchen infrastructure.
  • Generous on‑site parking.
  • 1.17 acres offering expansion or redevelopment potential.
Updated: Mar 5
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Versatile Commercial Building in Neosho
$1,095,000
4,814 SF

Versatile Commercial Building in Neosho

Adaptable commercial space with high visibility and development potential.

925 & 929 S Neosho Boulevard, Neosho, MO 64850
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Neosho Commercial Building For Sale
$825,000
3,828 SF

Neosho Commercial Building For Sale

Former Pizza Hut suitable for restaurant, retail, or office conversion.

648 S Neosho Boulevard, Neosho, MO 64850
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Highway Accessible Commercial Building
$280,000
3,360 SF

Highway Accessible Commercial Building

3,360 sq ft commercial building near I-49 and highways.

12619 Nettle Drive, Neosho, MO 64850
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Versatile Shop on Unrestricted Acres
$349,999
10.00 Acres

Versatile Shop on Unrestricted Acres

40x60 shop on 10+/- acres with no restrictions.

13504 Jay Drive, Neosho, MO 64850
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Neosho Commercial Building with Drive-Through
$160,000
1,221 SF

Neosho Commercial Building with Drive-Through

Well-designed commercial building in a high-convenience Neosho location.

115 E Hickory Street, Neosho, MO 64850
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Historic Neosho Square Mixed-Use Property
$349,900
4,120 SF

Historic Neosho Square Mixed-Use Property

4,120 sq ft mixed-use property on Neosho Square.

109 E Main Street, Neosho, MO 64850
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Established Floral & Gift Shop
$269,500
1,950 SF

Established Floral & Gift Shop

Profitable floral and gift shop in Neosho, Missouri for sale.

115 N College Street, Neosho, MO 64850
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Versatile 20-Acre Commercial Property
$549,999
2,400 SF

Versatile 20-Acre Commercial Property

20-acre property with shop, ideal for business and home.

13504 Jay Drive, Neosho, MO 64850
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Prime Land Near Highway 86
$321,650
9.00 Acres

Prime Land Near Highway 86

9.19 acre commercial land tract with excellent visibility.

Memory Lane, Neosho, MO 64850
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Commercial Land with I-49 Visibility
$650,000
10.00 Acres

Commercial Land with I-49 Visibility

10+/- acre commercial land with high I-49 visibility.

12229 Hammer Road, Neosho, MO 64850
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Turnkey Mechanic Shop For Sale
$899,999
3,100 SF

Turnkey Mechanic Shop For Sale

Profitable diesel mechanic shop with high visibility near I-49.

11628 Iris Road, Neosho, MO 64850
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Prime Commercial Land I-49 Frontage
$1,450,000
32.00 Acres

Prime Commercial Land I-49 Frontage

32-acre commercial development opportunity at I-49 and Highway 60.

12429 Nettle Drive, Neosho, MO 64850
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Updated Commercial Building in Neosho
$150,000
560 SF

Updated Commercial Building in Neosho

Move-in ready commercial building with versatile space and excellent visibility.

1577 N Business 49, Neosho, MO 64850
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Prime Commercial Land I-49 Frontage
$1,450,000
32.00 Acres

Prime Commercial Land I-49 Frontage

32-acre commercial land tract at I-49 and Highway 60.

12429 Nettle Drive, Neosho, MO 64850
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Waterfront Land with Nursery Setup
$295,000
14.00 Acres

Waterfront Land with Nursery Setup

14 acres of land with waterfront and commercial nursery.

18284 B-2 Gazelle Drive, Neosho, MO 64850
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Commercial Building in Neosho, MO
$99,800
2,805 SF

Commercial Building in Neosho, MO

Commercial building with parking and exterior signage in Neosho.

621 S Hamilton, Neosho, MO 64850
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I-49 Frontage Development Land
$599,900
3.00 Acres

I-49 Frontage Development Land

4 acres of commercial land with I-49 frontage.

Memory Lane, Neosho, MO 64850
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Neosho Land with Commercial Nursery
$745,000
110.00 Acres

Neosho Land with Commercial Nursery

110 acres featuring bottom land, woods, and nursery setup.

18284 1&B Gazelle Drive, Neosho, MO 64850
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Commercial Land with Highway Frontage
$620,000
6.00 Acres

Commercial Land with Highway Frontage

High-visibility commercial land with highway frontage and development potential.

1310 Reid Road, Neosho, MO 64850
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Prime Agricultural Land in Neosho
$489,471
58.00 Acres

Prime Agricultural Land in Neosho

58 acres near I-49, ideal for farming or development.

Gazelle Drive, Neosho, MO 64850
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Prime Land in Neosho, MO
$620,000
6.20 Acres

Prime Land in Neosho, MO

High-visibility commercial land with highway frontage in Neosho, Missouri.

1310 Reid Road, Neosho, MO 64850
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Prime Commercial Land Opportunity
$270,000
1.00 Acre

Prime Commercial Land Opportunity

1.43+/- acre commercial land parcel near I-49 & Hwy 86.

TBD-B E Highway 86, Neosho, MO 64850
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Neosho, MO Commercial Real Estate Investment Opportunities Market Analysis

Explore 46 commercial real estate for sale in Neosho, MO, showcased through 46 active listings on our real estate platform. These investment opportunities span a total of 27,010,685 square feet of properties for sale, with an estimated market value of $20,473,171.

Sale prices for business properties in Neosho, MO start at $48,000, averaging $435,599, and reaching up to $1,450,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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