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    Mcdonald County, MO Commercial Real Estate for Sale

    174 results
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    Prime Retail Location in Anderson
    $179,000
    3,465 SF

    Prime Retail Location in Anderson

    102 N Walnut St, Anderson, MO 64831

    Solid building in great location with many potential uses.

    • Prime business location at the end of main street, just off Hwy 59, with easy access to I‑49, Bentonville, AR, and Joplin, MO.
    • Solid brick and block construction with recent major improvements.
    • Versatile space suitable for business, office (with separate entry), or conversion to living quarters.
    • Spacious building at under $80 per sq ft, significantly less than new construction cost.
    • Includes a large walk‑in cooler, central heat and air, and all city utilities.
    Updated: Mar 11
    View details
    Turn-Key Restaurant Opportunity on Highway
    $575,000
    4,299 SF

    Turn-Key Restaurant Opportunity on Highway

    48 Little Missouri Rd, Jane, MO 64856

    Established restaurant and bar with high visibility on Highway 71.

    • Established bar and grill business with loyal customer base and strong income.
    • Turn‑key opportunity including all restaurant and bar equipment.
    • Prime commercial location with excellent visibility and easy access from Highway 71.
    • High‑traffic corner lot on Highway 71 and Little Missouri Road.
    • Owner financing available.
    Updated: Dec 11, 2025
    View details
    Prime Commercial Building in Anderson
    $179,000
    0.10 Acres

    Prime Commercial Building in Anderson

    Solid building in great location, ideal for various business ventures.

    102 N Walnut St, Anderson, MO 64831
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    Versatile Commercial Property in Anderson
    $185,000
    1,950 SF

    Versatile Commercial Property in Anderson

    Commercial property ideal for mechanic shop or other business uses.

    17 Stoneville Ln, Anderson, MO 64831
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    Versatile Commercial Property in Anderson
    $185,000
    1,950 SF

    Versatile Commercial Property in Anderson

    Commercial property ideal for mechanic shop or other business uses.

    17 Stoneville Ln, Anderson, MO 64831
    View details
    Versatile Building Near Interstate 49
    $199,000
    2,915 SF

    Versatile Building Near Interstate 49

    Open building near Interstate 49 in Goodman, Missouri.

    130 N Roy Hill Blvd, Goodman, MO 64843
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    Former Restaurant on Corner Lot
    $260,000
    2,893 SF

    Former Restaurant on Corner Lot

    2893 SF restaurant or retail space on 1.21 acres.

    1300 N Main St, South West City, MO 64863
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    Pineville Commercial Land Near Highway
    $550,000
    1.00 Acre

    Pineville Commercial Land Near Highway

    One-acre commercial lot near Highway 71 and Walmart facilities.

    111 Bear Hollow Rd, Pineville, MO 64856
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    Pineville, MO Redevelopment Opportunity
    $800,000
    1.50 Acres

    Pineville, MO Redevelopment Opportunity

    1.5 acre commercial lot near Highway 71 and Walmart facilities.

    111 Bear Hollow Rd, Pineville, MO 64856
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    Prime Commercial Land Near Highway
    $800,000
    1.50 Acres

    Prime Commercial Land Near Highway

    1.5-acre commercial lot near Highway 71 in Pineville, Missouri.

    111 Bear Hollow Rd, Pineville, MO 64856
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    Profitable Campground Investment Opportunity
    $309,000
    2,376 SF

    Profitable Campground Investment Opportunity

    10-acre short-term rental property near Huckleberry Ridge Conservation Area.

    2749 Route K, Pineville, MO 64856
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    Southwest City Commercial Opportunity
    $175,000
    3,120 SF

    Southwest City Commercial Opportunity

    Corner lot with retail, office, and warehouse space.

    211 S Main St, South West City, MO 64863
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    Versatile Commercial Property in Rocky Comfort
    $64,500
    0.04 Acres

    Versatile Commercial Property in Rocky Comfort

    Flexible commercial property with recent upgrades and endless possibilities.

    101 N Main St, Rocky Comfort, MO 64861
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    Pineville Restaurant and Nightclub Opportunity
    $699,000
    8,102 SF

    Pineville Restaurant and Nightclub Opportunity

    High-visibility commercial property with restaurant/nightclub, great traffic, and accessibility.

    76 Wright Hl, Pineville, MO 64856
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    Commercial Property with Rail Access
    $4,900,000
    41,344 SF

    Commercial Property with Rail Access

    Renovated warehouse with rail access and development potential.

    20040 Lark Rd, Goodman, MO 64843
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    Highway Frontage Development Opportunity
    $1,568,000
    3.50 Acres

    Highway Frontage Development Opportunity

    3.5 acre commercial land with high visibility and utilities.

    143 Missouri Ln, Pineville, MO 64856
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    Storage/Warehouse Space with Secure Yard
    $199,999
    2.00 Acres

    Storage/Warehouse Space with Secure Yard

    Commercial storage and warehouse property with highway exposure.

    303 O'brien Ln, Pineville, MO 64856
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    Storage/Warehouse Space with Secure Yard
    $199,999
    0.50 Acres

    Storage/Warehouse Space with Secure Yard

    Commercial storage and warehouse property with highway exposure for lease.

    303 O'brien Ln, Jane, MO 64856
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    Secure Warehouse Space with Yard
    Contact for pricing
    2,400 SF

    Secure Warehouse Space with Yard

    Functional storage/warehouse with secure yard and highway exposure.

    303 O'brien Ln, Jane, MO 64856
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    Pineville, MO Development Opportunity
    $1,400,000
    17.26 Acres

    Pineville, MO Development Opportunity

    17+ acre cleared parcel suitable for commercial or residential development.

    331 Shaddox Ln, Pineville, MO 64856
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    Warehouse with Secure Yard
    $199,999
    0.50 Acres

    Warehouse with Secure Yard

    Commercial storage/warehouse with highway exposure and secure, gated yard.

    303 O'brien Ln, Jane, MO 64856
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    85 Acres Recreational Property, Pineville
    $749,000
    85.00 Acres

    85 Acres Recreational Property, Pineville

    85-acre property with cabins, RV sites, and camping near state park.

    5641 Route K, Pineville, MO 64856
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    Highway Frontage Development Opportunity
    $1,568,000
    3.50 Acres

    Highway Frontage Development Opportunity

    3.5 acre commercial tract with Highway 71 frontage.

    143 Missouri Ln, Pineville, MO 64856
    View details
    Prime Commercial Land in Pineville
    $995,000
    6.00 Acres

    Prime Commercial Land in Pineville

    6-acre commercial land in a rapidly growing area near state line.

    21145 Us Highway 71, Pineville, MO 64856
    View details

    Mcdonald County, MO Commercial Real Estate Investment Opportunities Market Analysis

    Explore 110 commercial real estate for sale in Mcdonald County, MO, showcased through 174 active listings on our real estate platform. These investment opportunities span a total of 87,699,784 square feet of properties for sale, with an estimated market value of $42,644,401.

    Sale prices for business properties in Mcdonald County, MO start at $35,000, averaging $426,444, and reaching up to $4,900,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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