Madison County, MO Commercial real estate for sale

Updated: Jun 25

Drive-Through Restaurant Business

104 W College Avenue, Fredericktown, MO 63645

$249,900

1,127 sqft · 0.26 AC lot

Approx. 1,127 SF commercial property in downtown Fredericktown
Includes business equipment; negotiable as part of the sale
Walk‑in cooler and drive‑thru setup included
Block construction with concrete flooring
Fenced exterior

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Updated: Jun 2

Secluded Home on Wooded Acreage

2101 Madison 9236, Fredericktown, MO 63645

$550,000

1,344 sqft · 69.79 AC lot

69+/- acres of mostly wooded land offering hunting and recreational opportunities
New construction (2024) with modern amenities
Heated and cooled attached garage (40x31) - ideal for parking, storage, or hobbies
Stocked pond with bluegill and catfish
Granite countertops and stainless steel appliances

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Multi-Unit Office Building

120 E College, Fredericktown, MO 63645

$185,000

0.19 AC lot

Flexible office layout supports up to three separate suites with private offices, restrooms, and entrances.

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Pasture and Creekside Farm Land

10100 Highway 67, Fredericktown, MO 63645

$244,900

1,428 sqft · 29.64 AC lot

Nearly 30 acres of pasture and timber with spring-fed creek frontage and income-ready cattle fencing.

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Historic Train Depot Restaurant

406 Villar, Fredericktown, MO 63645

$499,999

1.48 AC lot

Full-service restaurant with 54-seat dining, bar seating, patio, curbside pickup, and included equipment on a 1.48-acre lot.

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Fredericktown Farm with Ranch Home

3978 Highway E Fredericktown Mo 63645, Fredericktown, MO 63645

$749,000

3,378 sqft · 24.00 AC lot

24-acre farm featuring a charming ranch-style home and outbuildings.

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Equestrian Homestead & Trail-Rider Paradise

100 Cool Breeze Lane, Fredericktown, MO 63645

$375,000

240 sqft · 20.00 AC lot

20-acre unrestricted property near premier trail-riding destinations.

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Commercial Land Corner Lot

Huddle House Drive, Fredericktown, MO 63645

$385,000

3.38 AC lot

Corner commercial acreage just off Hwy 67 and 72 with utilities available for flexible business development.

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Commercial Land with Major Road Frontage

Tract 5 off Hwy 72 Bypass, Fredericktown, MO 63645

$995,000

54.72 AC lot

Large commercially zoned tract with utilities onsite, plus extensive Hwy 72 Bypass and river frontage for flexible development.

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Fenced Hunting and Farm Land

9556 Madison 535, Fredericktown, MO 63645

$2,944,000

420.00 AC lot

Large tract with fields, timber, pond, and creek frontage, plus a cabin that needs updates.

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Recreation Acreage with New Shop Building

1104 Madison 311, Marquand, MO 63655

$135,000

3.22 AC lot

3.22 acres with a newly constructed 30' x 40' building and utilities for a flexible recreational or homestead buildout.

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Commercial Land Tract with Utilities

Tract 4 off Hwy 72 Bypass, Fredericktown, MO 63645

$150,000

1.04 AC lot

1.04-acre tract with electric and water on site, suitable for retail or restaurant concepts near major highway routes.

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Commercial Development Land

Tract 2 off Emerald Bluff Dr, Fredericktown, MO 63645

$195,000

1.84 AC lot

Nearly two acres of commercial land with three-sided road frontage and utilities available for flexible site development.

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Recreational Farm Land with Creek Frontage

10100 Highway 67, Fredericktown, MO 63645

$259,900

1,428 sqft · 29.60 AC lot

29.6-acre property with mostly open pasture, fencing, and nearly 500 feet along a year-round spring-fed creek.

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Industrial Buildings in Fredericktown, MO

701 Sargent Dr, Fredericktown, MO

$1,500,000

67,932 sqft · 8.04 AC lot

Two industrial buildings totaling 67,932 SF, ideal for manufacturing.

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Commercial Land with Two-Side Frontage

Tract 3 off Emerald Bluff Drive, Fredericktown, MO 63645

$150,000

1.00 AC lot

A 1-acre commercial tract with utilities on site and road frontage on two sides for flexible development planning.

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10.5 Acre Commercial Land Opportunity

6795 Business Highway 67, Fredericktown, MO 63645

$498,000

10.50 AC lot

Commercial land with highway access and existing infrastructure for sale.

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Land with Mineral Rights

S Mine La Motte Ave, Fredericktown, MO 63645

$900,000

81.00 AC lot

81-acre property outside town with described cobalt mineral rights and recreational hunting opportunities.

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Commercially Zoned Land For Sale

Hwy 72 Bypass, Fredericktown, MO

$995,000

54.72 AC lot

54.2 +/- acres in Fredericktown, MO with highway frontage.

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Commercial Building in Marquand, Missouri

117 N Whitener Street, Marquand, MO 63655

$119,900

Commercial building for sale in Marquand, Missouri.

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Retail Property in Fredericktown, MO

605 E Hwy 72, Fredericktown, MO

$510,000

0.82 AC lot

Retail property for sale in Fredericktown, Missouri.

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Ozark Land with Spring-Fed Creek

129 Madison CR 410, Fredericktown, MO 63645

$49,900

2.50 AC lot

2.5+/- acres with creek, camping spot near Mark Twain Forest.

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Commercial Lot with High Visibility

1261 West Main Street, Fredericktown, MO 63645

$100,000

0.75 AC lot

Approximately 0.75 acre commercial lot with high traffic exposure.

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Commercially Zoned Land For Sale

Emerald Bluff Dr, Fredericktown, MO

$295,000

16.07 AC lot

16.07 acre commercially zoned land with utilities in Fredericktown, MO.

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