Lee County, IA Commercial Real Estate for Sale

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52 properties
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Multi-Building Industrial Flex Property
Updated: Jul 23
Multi-Building Industrial Flex Property

128 N 19th Street, Keokuk, IA 52632

$210,000
2.00 AC lot
Approximately 2.5‑acre Keokuk, IA commercial property with three separate buildings totaling 9,825 SF
Includes a 625‑SF office building for administrative space or customer reception
Two shop buildings offer 4,800 SF and 4,400 SF of flexible commercial/industrial/service space
One shop features a heated work area and a restroom for year‑round operations
Forced‑air heating; public water service
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Mixed-Use Storefront with Upper-Level Space
Updated: Jul 28
Mixed-Use Storefront with Upper-Level Space

711 Avenue G, Fort Madison, IA 52627

$109,500
0.08 AC lot
Main‑floor tenant in place through May 2028
Unfinished upper level offers additional configurable space
Brick construction dating to 1890
Forced‑air heating and central air conditioning
Public water service and on‑street parking
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Modern Storefront with Bakery Business
Modern Storefront with Bakery Business

423 Avenue D, West Point, IA 52656

$275,000
0.12 AC lot

Built in 2020 with central air, forced-air heating, and an accessible ramp approach.

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See what stands out in Lee County

We check every for-sale listing in the county against comparable properties across the country. Most price about where you would expect. A few are worth a second look.

We check every listing here. A few are worth a second look.

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River City Mall Shopping Center
River City Mall Shopping Center

300 Main St, Keokuk, IA 52632

$600,000
208,492 sqft 9.00 AC lot

Multi-unit retail center with highway access, theater space, and substantial redevelopment needs.

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Flexible Flex Space with Open Layout
Flexible Flex Space with Open Layout

419 N Oak Street, Donnellson, IA 52625

$150,000
0.12 AC lot

Well-maintained commercial building with adaptable rooms, multiple entrances, kitchen area, and updated mechanical and exterior components.

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Three-Story Wedding & Event Center
Three-Story Wedding & Event Center

619 Blondeau Street, Keokuk, IA 52632

$800,000
0.39 AC lot

Meyers Courtyard is a three-story, brick venue with 7 leased spaces, elevator access, and an event center with kitchen and bar.

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Victorian Mixed-Use Building
Victorian Mixed-Use Building

809 Ave G, Fort Madison, IA 52627

$147,900
0.08 AC lot

Brick construction combines a ground-floor storefront with an upper-level apartment.

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Flexible Warehouse and Office Space
Flexible Warehouse and Office Space

419 N Oak St, Donnellson, IA 52625

$150,000
3,485 sqft

Versatile 41' x 85' building on a concrete slab with open gathering areas, private enclosed section, and multiple exterior entries.

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Mixed-Use Bar and Restaurant
Mixed-Use Bar and Restaurant

707 Main Street, Keokuk, IA 52632

$350,000
0.13 AC lot

Main Street property combines an equipped dining and bar operation with two upstairs rental apartments and a rear patio.

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Downtown Brick Office Building
Downtown Brick Office Building

313 5th St, West Point, IA 52656

$72,000
0.17 AC lot

Brick commercial building with adaptable space, two half baths, and public water service.

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Recreational Hunting Estate with Tillable Acres
Recreational Hunting Estate with Tillable Acres

1537 270th St, Argyle, IA 52619

$2,755,000
4,480 sqft 340.00 AC lot

340-acre estate includes a 4-bedroom home, multiple outbuildings, stocked ponds, and about 75 acres of leased tillable ground.

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CRP-Enrolled Agricultural Land
CRP-Enrolled Agricultural Land

Valley Road, Keokuk, IA 52632

$129,900
13.00 AC lot

Rural acreage combines an active CRP enrollment with habitat suited to deer, turkey, and pheasant hunting.

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Keokuk Land Development Opportunity
Keokuk Land Development Opportunity

Main, Keokuk, IA 52632

$289,000
14.47 AC lot

Prime land parcel with high visibility and development potential.

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Freestanding Retail Storefront
Freestanding Retail Storefront

2505 280th St, Montrose, IA 52639

Contact for pricing
9,092 sqft 1.88 AC lot

Vacant, one-story commercial space with dual-road access and on-site parking.

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Brick School Building with Gymnasium
Brick School Building with Gymnasium

914 Timea Street, Keokuk, IA 52632

$255,000
0.80 AC lot

Former educational facility with classrooms, offices, and a refurbished gymnasium.

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Flex Property with Workshop
Flex Property with Workshop

1404 Avenue M, Fort Madison, IA 52627

$119,900
2.16 AC lot

Two-building setup combines office, service, and storage areas with outdoor space for operational flexibility.

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Flex Space with Three Buildings
Flex Space with Three Buildings

128 N 19th Street, Keokuk, IA 52632

Contact for pricing
9,825 sqft 2.50 AC lot

Versatile flex space with an on-site office and two shop buildings, with ample outdoor and equipment access.

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Agricultural Land with Outbuildings
Agricultural Land with Outbuildings

1880 265Th Avenue, Fort Madison, IA 52627

$119,000
5.40 AC lot

Rural acreage includes utility improvements, a pole barn with stables, electricity, and water.

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Downtown Storefront Building
Downtown Storefront Building

313 5th St, West Point, IA 52656

Contact for pricing
1,200 sqft

Storefront space with an adaptable existing layout and two half baths in a downtown setting.

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Mixed-Use Building with Storefronts
Mixed-Use Building with Storefronts

606-610 9Th Street, Fort Madison, IA 52627

$95,000
11.00 AC lot

Three ground-floor storefronts are positioned beneath four one-bedroom apartments in a historic commercial building.

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Former Rehabilitation and Care Facility
Former Rehabilitation and Care Facility

901 State Street, Donnellson, IA 52625

$380,000
23,051 sqft

23,000+ sqft former rehabilitation facility with 46 beds.

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Commercial Land in Fort Madison
Commercial Land in Fort Madison

4420 Ave L, Fort Madison, IA 52627

$125,000
2.62 AC lot

2.62-acre commercial land ideal for development in Fort Madison, Iowa.

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Multi-Building Industrial Warehouse
Multi-Building Industrial Warehouse

1823 33rd St, Fort Madison, IA 52627

Contact for pricing
25,000 sqft 2.41 AC lot

Three-building industrial facility with office, warehouse, loading, parking, and outdoor storage capacity.

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Tillable Agricultural Land
Tillable Agricultural Land

2625 346th, Keokuk, IA 52632

$78,000
8.60 AC lot

Open farmland with a dedicated roadway tract and a Rathbun water meter already on site.

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Lee County, IA Commercial Real Estate Market Trends and Statistics

Explore 72 commercial real estate for sale in Lee County, IA, showcased through 52 active listings on our real estate platform. These investment opportunities span a total of 494,458 square feet of properties for sale, with an estimated market value of $9,789,200.

Sale prices for business properties in Lee County, IA start at $50,000, averaging $337,558, and reaching up to $2,755,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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