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    Madison County, OH Commercial Real Estate for Lease

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    Columbus, OH Cincinnati, OH Cleveland, OH
    31 listings
    West Jefferson Medical/Office Space
    $10 SF/Yr
    2,250 SF
    West Jefferson Medical/Office Space

    487 West Main Street, West Jefferson, OH 43162

    Single-story medical/office space available for lease in West Jefferson, OH.
    • Convenient location directly off Main St and National Pk 90/Broad St in West Jefferson.
    • Single‑story building suitable for general or medical office.
    • 2,200 SF Suite E available.
    • Former Pharmacy Space.
    • Generous parking available.
    Updated: Nov 22, 2025
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    Retail Space on Main Street
    $16 SF/Yr
    1,686 SF
    Retail Space on Main Street

    229-275 E Main St, West Jefferson, OH

    Retail spaces available in West Jefferson with high visibility.
    • Prime location on E Main Street / US 40 in West Jefferson.
    • Fully contiguous space of 4,000 SF or divisible into 1,686 SF and 2,008 SF spaces.
    • Recently white boxed with new LED lighting, drop ceiling, and restrooms.
    • Excellent visibility with street frontage on Main Street.
    • High traffic count of over 13,500 cars per day.
    Updated: Nov 23, 2025
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    Retail Space Available For Lease
    $24 SF/Yr
    40,000 SF
    Retail Space Available For Lease

    Divisible retail space available 10 months after lease signing.

    7693 Corporate Blvd, Plain City, OH

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    New Industrial Complex Under Construction
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    14,000 SF
    New Industrial Complex Under Construction

    New industrial complex with flexible suite sizes available for rent.

    8300 Warner Road, Plain City, OH 43064

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    Corporate Blvd Warehouse Space
    Contact for pricing
    3,000 SF
    Corporate Blvd Warehouse Space

    Warehouse space near I-270 and I-70.

    7710 Corporate Blvd., Plain City, OH 43064

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    Warehouse and Retail Spaces Available
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    3,027 SF
    Warehouse and Retail Spaces Available

    Warehouse and retail spaces for lease in London, OH.

    235 Lafayette St, London, OH

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    New Industrial Space Available
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    21,000 SF
    New Industrial Space Available

    New industrial warehouse space for lease, delivery Q1 2026.

    7685 Commerce Pl, Plain City, OH

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    Industrial Space Available For Lease
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    14,400 SF
    Industrial Space Available For Lease

    New industrial space for lease, delivery Q1 2026.

    8000 Industrial Pkwy, Plain City, OH

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    Industrial Parkway Retail Opportunity
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    Industrial Parkway Retail Opportunity

    Retail space available in a high-growth area near Dublin.

    6800 Industrial Parkway, Plain City, OH 43064

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    Historic Office Space in Plain City
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    2,677 SF
    Historic Office Space in Plain City

    Restored office space in a historic Plain City building.

    125 W Main St, Plain City, OH 43064

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    Retail Space Near Planned Residences
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    40,895 SF
    Retail Space Near Planned Residences

    Retail opportunity near Costco, Aldi, and planned residential developments.

    Weldon Rd, Plain City, OH

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    Prime Industrial Land for Lease
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    789,630 SF
    Prime Industrial Land for Lease

    Industrial land with tax abatement and highway access available for lease.

    4580 US Hwy 40, West Jefferson, OH

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    Industrial Warehouse Space Available
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    343,500 SF
    Industrial Warehouse Space Available

    Class A warehouse space for lease in West Jefferson, OH.

    US Highway 40, West Jefferson, OH

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    Industrial Space Available For Lease
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    24,712 SF
    Industrial Space Available For Lease

    Industrial property with 24,712 square feet available for lease.

    7858 Industrial Parkway, Plain City, OH 43064

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    C5 Gateway Logistics Center
    Contact for pricing
    747,520 SF
    C5 Gateway Logistics Center

    747,520 SF distribution center near Interstate 70.

    1050 Gateway Park Dr, West Jefferson, OH

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    Modern Distribution Warehouse in West Jefferson
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    832,600 SF
    Modern Distribution Warehouse in West Jefferson

    832,600 SF warehouse space available for lease.

    1020 Enterprise Pkwy, West Jefferson, OH

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    Warehouse Space For Lease
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    3,200 SF
    Warehouse Space For Lease

    2,666 SF warehouse space available for lease.

    231-235 Lafayette St, London, OH

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    Industrial Space Available for Lease
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    734,160 SF
    Industrial Space Available for Lease

    Industrial space available for lease at Park 70 East.

    15 Commerce Pkwy, West Jefferson, OH

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    Available Warehouse Space in Plain City
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    9,000 SF
    Available Warehouse Space in Plain City

    9,000 SF warehouse space with ample parking.

    7637 Commerce Pl, Plain City, OH

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    West Jefferson Logistics Center Space
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    1,841,747 SF
    West Jefferson Logistics Center Space

    Large distribution center space near major transportation routes.

    1025 Enterprise Pkwy S, West Jefferson, OH

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    West Jefferson Warehouse For Sale
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    1,090,000 SF
    West Jefferson Warehouse For Sale

    Large industrial warehouse with ample parking and modern amenities.

    44 Commerce Pkwy, West Jefferson, OH

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    Flex Space in Commercial District
    $204 SF/Yr
    Flex Space in Commercial District

    All-inclusive warehouse, office, and flex space for small businesses.

    7780 Corporate Blvd, Plain City, OH 43064

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    Industrial Space Available for Lease
    Contact for pricing
    542,640 SF
    Industrial Space Available for Lease

    Industrial space available for lease at Park 70 East.

    SR-29 & National Pike, West Jefferson, OH

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    Industrial Space Available For Lease
    Contact for pricing
    669,760 SF
    Industrial Space Available For Lease

    Industrial space available for lease at Park 70 East.

    Park 70 East, West Jefferson, OH

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    Madison County, OH Commercial real estate Market Trends and Statistics

    Explore Commercial real estate leasing options in Madison County, OH with 31 listings featured on our commercial real estate exchange. The current inventory includes 43,936 square feet of properties with an estimated lease value of $50 SF/Yr.

    Estimated lease rates for Commercial real estate in Madison County, OH begin at $10 SF/Yr, with an average of $16 SF/Yr and extend to $24 SF/Yr.
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