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Defiance County, OH Commercial Real Estate for Lease

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13 results
Retail Space in Defiance, OH
$20 SF/Yr
12,850 SF

Retail Space in Defiance, OH

8959 State Route 66 N, Defiance, OH 43512

3,150 SF retail space available in neighborhood retail center.

  • Prime location at the signalized intersection of State Route 66 and Elliott Rd, near State Route 24 interchange.
  • High visibility with 147 ft of frontage on State Route 66.
  • Located in a strong retail corridor near Walmart, Meijer, Kohls, and other national retailers.
  • Marquee and facade signage opportunities available.
  • Ample paved parking.
Updated: Nov 21, 2025
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Historic Downtown Building Renovation
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Historic Downtown Building Renovation

300 Clinton Street, Defiance, OH 43512

Renovated historic building with restaurant and office space.

  • Prime "Main and Main" location at the busiest intersection in downtown Defiance.
  • Major historic renovation of the building.
  • Main floor restaurant space available to be built out.
  • Potential for outdoor dining area.
  • Second and third floor office suites available to be built out.
Updated: Mar 6
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Historic Downtown Building Renovation
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13,200 SF

Historic Downtown Building Renovation

Prime location for restaurant or office space in Defiance, OH.

300 Clinton Street, Defiance, OH 43512
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Free Standing Building For Rent
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14,564 SF

Free Standing Building For Rent

14,564 SF building with mezzanine and drive-up window.

618 North Clinton Street, Defiance, OH 43512
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Industrial Facility in Defiance, Ohio
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70,000 SF

Industrial Facility in Defiance, Ohio

70,000 SF industrial facility, expandable to 100,000 SF.

25490 Commerce Drive (Spec Building), Defiance, OH 43512
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Retail Space with High Visibility
$20 SF/Yr
3,150 SF

Retail Space with High Visibility

Retail space with frontage on State Route 66.

8959 OH-66, Defiance, OH
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Retail Space Near Kroger
$8 SF/Yr
9,217 SF

Retail Space Near Kroger

Retail space available in shadow-anchored shopping center.

1838-1858 E 2nd St, Defiance, OH
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Defiance Office Space Available
$8 SF/Yr
6,000 SF

Defiance Office Space Available

6,000 square feet of office space for rent.

24862 Elliott Rd, Defiance, OH
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Defiance Retail Space For Lease
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5,250 SF

Defiance Retail Space For Lease

Retail or office space with high visibility and ample parking.

319 E 2 St, Defiance, OH
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Historic Building in Downtown Defiance
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Historic Building in Downtown Defiance

Renovated historic building with restaurant and office space.

300 Clinton Street, Defiance, OH 43512
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Retail Space in Prime Location
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3,150 SF

Retail Space in Prime Location

3,150 SF retail space in well-maintained strip center.

8959 OH-66, Defiance, OH 43512
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Modern Retail/Office Center For Rent
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20,056 SF

Modern Retail/Office Center For Rent

20,056 SF retail/office center constructed in 2013.

100 Stadium Drive, Defiance, OH 43512
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Defiance Retail Space Available
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Defiance Retail Space Available

Retail spaces for rent at 1838 & 1858 E. Second Street.

1838 & 1858 E. Second Street, Defiance, OH 43512
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Based on your search, we've compiled 28 Potential Opportunities for your consideration. Besides 13 Active listings in Defiance County, OH, we suggest exploring alternatives. Similar 15 Properties for Sales.

Explore Similar Spaces for Sale in Defiance County, OH

Consider Similar Space for Sale. We found 15 Spaces matching your search parameters.

Commercial Site on Stadium Drive
$225,000

Commercial Site on Stadium Drive

Commercial land suitable for QSR or retail development.

57 Stadium Drive, Defiance, OH 43512
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In-Line Shopping Center For Sale
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20,056 SF

In-Line Shopping Center For Sale

20,056 SF shopping center with move-in ready suites.

100 Stadium Dr, Defiance, OH 43512
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Hicksville Landmark Retail Opportunity
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1,025 SF

Hicksville Landmark Retail Opportunity

Well-known restaurant property with high visibility and traffic.

961 E High St, Hicksville, OH 43526
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Commercial Site on Stadium Drive
$225,000

Commercial Site on Stadium Drive

Prime commercial land suitable for QSR, retail, and drive-thru concepts.

57 Stadium Drive, Defiance, OH 43512
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Retail Space on High Street
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1,025 SF

Retail Space on High Street

Retail space available for sale, 1,025 square feet.

134 E High St, Hicksville, OH 43526
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Industrial Land Parcels Available
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Industrial Land Parcels Available

45-acre industrial land with M-2 and M-3 zoning.

East Commerce Dr, Defiance, OH 43512
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Highway Exposure Industrial Land
$181,320
3.02 Acres

Highway Exposure Industrial Land

Fully developed industrial land ready for construction with highway exposure.

167 Fox Run Dr, Defiance, OH
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Industrial Land in Northwest Ohio
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45.00 Acres

Industrial Land in Northwest Ohio

Industrial land for sale in Defiance, Ohio.

East Commerce Dr, Defiance, OH
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Industrial Land with Highway Exposure
$120,000
2.00 Acres

Industrial Land with Highway Exposure

Highway-exposed, fully developed industrial land ready for construction.

83 Fox Run Dr, Defiance, OH
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Prime Commercial Land Opportunity
$250,000
2.12 Acres

Prime Commercial Land Opportunity

2.12 acre commercial land for sale in Defiance, OH.

575 Cleveland Ave, Defiance, OH
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Commercial Land Next to Kohl's
$500,000

Commercial Land Next to Kohl's

1.02 acres of commercial land for sale.

8683 N Clinton St, Defiance, OH 43512
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Defiance County, OH Commercial real estate Leasing Opportunities Market Analysis

Explore Commercial real estate leasing options in Defiance County, OH with 13 listings featured on our commercial real estate exchange. The current inventory includes 800,066,520 square feet of properties with an estimated lease value of $36 SF/Yr.

Estimated lease rates for Commercial real estate in Defiance County, OH begin at $8 SF/Yr, with an average of $12 SF/Yr and extend to $20 SF/Yr.
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