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Florence, MS Commercial Real Estate for Lease

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Retail Building on Highway 49
$6,000 /Mo
6,000 SF

Retail Building on Highway 49

2851 Us 49, Florence, MS 39073

Freestanding retail building with high visibility in Florence, Mississippi.

  • High‑traffic location with excellent visibility on Highway 49 (31,000+ vehicles per day).
  • Freestanding 6000 sq ft open clear span retail space.
  • Ample parking and accessibility.
  • Located in a growing area with shopping, dining, and recreational amenities.
  • Contemporary design with highly customizable interior.
Updated: Jun 5, 2025
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Based on your search, we've compiled 35 Potential Opportunities for your consideration. Besides 1 Active listings in Florence, MS, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 30 Properties for Sales.

Explore Commercial real estate for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Industrial Space with Truck Shop
$6 SF/Yr
215,000 SF

Industrial Space with Truck Shop

Divisible industrial space with truck shop and outside storage.

1125 Weems Street, Pearl, MS 39208
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Richland Industrial Space Available
Contact for pricing
1,067 SF

Richland Industrial Space Available

Industrial spaces available for rent in Richland, Mississippi.

542 Industrial Dr, Richland, MS 39218
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Retail Suite on U.S. Hwy 49
Contact for pricing
1,352 SF

Retail Suite on U.S. Hwy 49

1,352 SF retail suite with highway frontage available for lease.

890 US 49, Richland, MS
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Rankin County Industrial Space Available
Contact for pricing
130,000 SF

Rankin County Industrial Space Available

Industrial space for lease or purchase in Rankin County, MS.

1125 Weems St, Pearl, MS 39208
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Explore Similar Spaces for Sale in Florence, MS

Consider Similar Space for Sale. We found 30 Spaces matching your search parameters.

Versatile Florence Property on Five Acres
$945,000
7,401 SF

Versatile Florence Property on Five Acres

Unique property with two homes, ideal for various uses.

219 Bass Road, Florence, MS 39073
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Unique Sprawling Property on Five Acres
$945,000
7,401 SF

Unique Sprawling Property on Five Acres

Versatile property with two homes, ideal for retreat or care facility.

219 Bass Road, Florence, MS 39073
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Industrial Building with Office Space
$495,000
11,320 SF

Industrial Building with Office Space

Industrial building with offices, storage, and yard space for sale.

778 N Church Street, Florence, MS 39073
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Highway Frontage Commercial Land
$95,000
0.66 Acres

Highway Frontage Commercial Land

Prime commercial land with high visibility on Highway 49.

3193 U.S. 49, Florence, MS 39073
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Prime Commercial Land in Florence
$589,000
79,715 SF

Prime Commercial Land in Florence

1.83-acre corner parcel with high visibility and accessibility.

118 Crosspark Drive, Florence, MS 39073
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Spacious Multipurpose Building in Star
$415,000
7,972 SF

Spacious Multipurpose Building in Star

Versatile 7,972 sqft building ideal for daycare or community initiatives.

154 Dixie Drive, Florence, MS 39073
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Undeveloped Commercial Lot on Highway
$495,000
7.95 Acres

Undeveloped Commercial Lot on Highway

7.95 acre commercial lot with highway frontage in Florence, MS.

Florence Drive, Florence, MS 39073
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Prime Corner Lot For Sale
$800,000
62,726 SF

Prime Corner Lot For Sale

Corner lot with high visibility on Highway 49.

1114 Gunter Road, Florence, MS 39073
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Highway 49 Commercial Land Opportunity
$575,000

Highway 49 Commercial Land Opportunity

Highly visible commercial land on Highway 49 in Florence, MS.

2105 U.S. 49, Florence, MS 39073
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Corner Lot on Highway 49
$1,175,000
100,567 SF

Corner Lot on Highway 49

High-visibility commercial land at a major intersection.

1110 Gunter Road, Florence, MS 39073
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Commercial Land on Highway 49
$800,000
62,726 SF

Commercial Land on Highway 49

Prime corner lot with high visibility on Highway 49.

1114 Gunter Road, Florence, MS 39073
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Commercial Lot on Highway 49
$653,400
1.00 Acre

Commercial Lot on Highway 49

Commercial lot with high traffic flow on Highway 49.

0005 Cross Park Dr. Lot #5, Florence, MS 39073
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Prime Commercial Land on Highway
$2,250,000
897,771 SF

Prime Commercial Land on Highway

20.61-acre C3-zoned property on Highway 49 in Florence, MS.

2487 Highway 49, Florence, MS 39073
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Undeveloped Commercial Lot in Florence
$495,000
7.95 Acres

Undeveloped Commercial Lot in Florence

7.95 acre commercial lot with highway frontage in Florence, MS.

Florence Dr, Florence, MS
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Commercial Land in Florence, MS
$260,000
31,799 SF

Commercial Land in Florence, MS

Commercial land suitable for business or residential use.

1118 Gunter Road, Florence, MS 39073
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Highway Frontage Commercial Land
$1,200,000
5.00 Acres

Highway Frontage Commercial Land

Commercial land with high traffic visibility on Highway 49.

3327 US 49 S, Florence, MS
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Prime Corner Commercial Lots
$1,060,000
100,567 SF

Prime Corner Commercial Lots

High-visibility commercial land at a signalized intersection in Florence, MS.

1110 Gunter Road, Florence, MS 39073
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Prime Commercial Land For Sale
$589,000
79,715 SF

Prime Commercial Land For Sale

1.83-acre corner parcel with high visibility and accessibility.

118 Crosspark Drive, Florence, MS 39073
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29 Acre Commercial Site
$1,894,872
29.00 Acres

29 Acre Commercial Site

High visibility commercial land on Highway 49 in Florence, MS.

Highway 49, Florence, MS 39073
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Commercial Land on Highway 49
$575,000
4.08 Acres

Commercial Land on Highway 49

Highly visible commercial land opportunity on Highway 49 in Florence.

2105 US 49, Florence, MS
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Highway 49 Commercial Land Opportunity
$575,000

Highway 49 Commercial Land Opportunity

Highly visible commercial land on Highway 49 in Florence, MS.

2105 US 49, Florence, MS 39073
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Highway 49 Frontage Industrial Property
$550,000

Highway 49 Frontage Industrial Property

Prime industrial land with Highway 49 frontage in Florence, MS.

1764 US 49, Florence, MS 39073
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Commercial Lot on Hwy 49
$850,000

Commercial Lot on Hwy 49

Commercial lot with high traffic flow on Hwy 49.

1 Hwy 49 Unit Lot #1, Florence, MS 39073
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Florence, MS Commercial real estate Leasing Opportunities Market Analysis

Explore Commercial real estate leasing options in Florence, MS with 1 listings featured on our commercial real estate exchange. The current inventory includes 522,720,000 square feet of properties with an estimated lease value of $22 SF/Yr.

Estimated lease rates for Commercial real estate in Florence, MS begin at $10 SF/Yr, with an average of $11 SF/Yr and extend to $12 SF/Yr.
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