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Spencer, MA Commercial Real Estate for Lease

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Versatile Commercial Space in Spencer
$1,250 / Mo
2,365 SF

Versatile Commercial Space in Spencer

200 Main St, Spencer, MA 01562

Adaptable retail space near transportation, schools, and town amenities.

  • Versatile space SUITABLE FOR VARIOUS USES.
  • Convenient location near public transportation, schools, and town center amenities.
  • Heat included in the modified gross lease.
  • Easy to show.
  • Historic building BUILT IN 1850.
Updated: Sep 30, 2025
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Prime Spencer Medical Office Space
$22 SF/Yr
13,273 SF

Prime Spencer Medical Office Space

407 Main St, Spencer, MA 01562

6,271 SF Medical Office Available

  • 6,271 SF medical office suite available for immediate occupancy at 407 E. Main Street, Spencer, MA 01562.
  • Located in a 13,273 SF Class C multi‑tenant building with ample parking (8 spaces/1,000 SF).
  • Features exam rooms, consultation rooms, check‑in counters, and reception areas.
  • Previously used for internal medicine; ideal for various medical specialties.
  • Turnkey solution for medical practices seeking established space in Spencer, MA.
Updated: Dec 11, 2024
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Retail Space For Lease
$4,000 / Mo

Retail Space For Lease

Retail space available for lease with heavy vehicle traffic.

160 Main St, Spencer, MA 01562
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Retail Space on Route 9
Contact for pricing
1,329 SF

Retail Space on Route 9

Retail space available on a busy thoroughfare, Route 9.

72 W Main St, Spencer, MA 01562
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Based on your search, we've compiled 17 Potential Opportunities for your consideration. Besides 4 Active listings in Spencer, MA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 9 Properties for Sales.

Explore Commercial Real Estate for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Retail Space Near Walmart
Contact for pricing
2,100 SF

Retail Space Near Walmart

Retail space for rent, located across from Walmart.

1603 Main St, Leicester, MA 01524
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Retail Space in Mixed-Use Development
Contact for pricing
2,400 SF

Retail Space in Mixed-Use Development

Retail and restaurant spaces available in Leicester, Massachusetts.

1434 Main St, Leicester, MA 01524
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Industrial Outdoor Storage Land
Contact for pricing

Industrial Outdoor Storage Land

5.33 acres of industrial outdoor storage land for rent.

140 Goddard Memorial Dr, Worcester, MA 01603
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Versatile Building Near Worcester Airport
Contact for pricing
10,000 SF

Versatile Building Near Worcester Airport

10,000 SF building suitable for office, medical, or industrial use.

170 Goddard Memorial Dr, Worcester, MA 01602
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Explore Similar Spaces for Sale in Spencer, MA

Consider Similar Space for Sale. We found 9 Spaces in Nearby Locations matching your search parameters.

Custom Ranch with Horse Barn
$769,900

Custom Ranch with Horse Barn

29.91-acre ranch featuring a horse barn and custom details.

54 Hastings Rd, Spencer, MA 01562
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Townhouse Court Multifamily Investment
$4,100,000

Townhouse Court Multifamily Investment

Value-add multifamily opportunity in Spencer, Massachusetts with upside potential.

Town House Ct, Spencer, MA 01562
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Updated Two-Family Home with Yard
$499,900

Updated Two-Family Home with Yard

Updated two-family home, ideal for owner-occupancy or multi-generational living.

13 Grove St, Spencer, MA 01562
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Turnkey Multifamily Property in Spencer
$589,000

Turnkey Multifamily Property in Spencer

Fully occupied 3-unit multifamily with potential for a 4th unit.

50 Pleasant St, Spencer, MA 01562
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Queen Anne Victorian with Updates
$525,000

Queen Anne Victorian with Updates

Updated Queen Anne Victorian with business opportunity in Spencer, MA.

232 Main St, Spencer, MA 01562
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Established Pub with Event Room
$795,000

Established Pub with Event Room

Well-established bar business with event room and commercial kitchen.

40 Chestnut St, Spencer, MA 01562
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Spacious Three-Family Investment Property
$475,000

Spacious Three-Family Investment Property

Income-producing three-family property with long-term tenants and a vacant unit.

52 Grove St, Spencer, MA 01562
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Renovated Two-Family Home
$529,900

Renovated Two-Family Home

Updated two-family property, ideal for investors or owner-occupants.

26 Maple St, Spencer, MA 01562
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Historic Spencer Commercial Building
$329,900
0.22 Acres

Historic Spencer Commercial Building

Prime Downtown Location, High Potential

62 Wall St, Spencer, MA 01562
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Spencer, MA Commercial Real Estate Leasing Opportunities Market Analysis

Explore Commercial Real Estate leasing options in Spencer, MA with 13 listings featured on our commercial real estate exchange. The current inventory includes 681,191,280 square feet of properties with an estimated lease value of $28 SF/Yr.

Estimated lease rates for Commercial Real Estate in Spencer, MA begin at $6 SF/Yr, with an average of $14 SF/Yr and extend to $22 SF/Yr.

In Spencer, MA, current lease rates show:

  • Fitness centers & gyms positioned at $6
  • Healthcare properties measuring $22
  • Individual retail properties assessed at $6
  • Medical offices calculated at $22
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