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    Opelousas, LA Commercial Real Estate for Lease

    11 results
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    Modern Medical Office in Opelousas
    Contact for pricing
    6,000 SF

    Modern Medical Office in Opelousas

    1418 Heather Dr, Opelousas, LA 70570

    State-of-the-art medical office space for lease.

    • State‑of‑the‑art medical office/surgical center with approximately 6,000 sq ft of versatile space.
    • Prime location with high visibility and easy access off I‑49 at the Judson Walsh exit.
    • Close proximity to Opelousas General South Campus and Opelousas General North Campus.
    • Approximately 20 minutes from Lafayette, LA.
    • Large parking lot with ample off‑street parking.
    Updated: Jan 16
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    Opelousas Office Space For Rent
    $197,500
    2,100 SF

    Opelousas Office Space For Rent

    223 S Main St, Opelousas, LA 70570

    Spacious office in Opelousas Opportunity Zone with modern amenities.

    • Prime location in an Opportunity Zone with Main Street frontage.
    • Walking distance to the courthouse and across from the St. Landry Bank Building.
    • Includes multiple offices (3 small, 2 large) and a conference room.
    • Full bath with new stand‑up shower and half bath.
    • Large kitchen/break room with brand new appliances included.
    Updated: Jan 12
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    Versatile Office Building For Lease
    Contact for pricing
    9,000 SF

    Versatile Office Building For Lease

    Two-story building ideal for medical or professional office use.

    4049 I 49 S Service Rd, Opelousas, LA 70570
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    Opelousas Commercial Building For Lease
    Contact for pricing
    1,665 SF

    Opelousas Commercial Building For Lease

    Commercial building in high-traffic area, ideal for retail or offices.

    1004 Creswell Ln, Opelousas, LA 70570
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    Opelousas Office Space For Lease
    Contact for pricing
    2,100 SF

    Opelousas Office Space For Lease

    Move-in ready office space in the heart of Opelousas.

    414 S Main St, Opelousas, LA 70570
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    Industrial Building on Two Acres
    Contact for pricing
    4,800 SF

    Industrial Building on Two Acres

    4800SF industrial building with I-49 frontage on 2 acres.

    3383 I 49 S Service Rd, Opelousas, LA 70570
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    Opelousas Commercial Corner Lot
    $5,900 / Mo
    39,640 SF

    Opelousas Commercial Corner Lot

    Corner lot in fast food corridor, ideal for restaurant.

    1130 S Union St, Opelousas, LA 70570
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    Opelousas Warehouse For Rent
    Contact for pricing
    2,940 SF

    Opelousas Warehouse For Rent

    Secure 2,940 sq ft warehouse on 0.27 acres.

    8599 Highway 182, Opelousas, LA 70570
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    Move-in Ready Medical Office
    Contact for pricing
    3,200 SF

    Move-in Ready Medical Office

    3200 sq ft medical office building ready for occupancy.

    1110 A C Terrance Unit, Opelousas, LA 70570
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    Medical/Professional Office Building For Lease
    $9,000 / Mo

    Medical/Professional Office Building For Lease

    Two-story building ideal for medical or professional office use.

    4049 I 49 S Service Rd, Opelousas, LA 70570
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    Retail Space in Opelousas
    Contact for pricing
    7,200 SF

    Retail Space in Opelousas

    7,200 SF retail space available for rent.

    2418 South Union St, Opelousas, LA 70570
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    Based on your search, we've compiled 15 Potential Opportunities for your consideration. Besides 11 Active listings in Opelousas, LA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities

    Explore Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Commercial Land in Carencro, LA
    $599,000
    4,000 SF

    Commercial Land in Carencro, LA

    Located off I-49, high-traffic frontage road.

    4300 NE Evangeline Thruway, Carencro, LA 70520
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    Retail/Office Space in Carencro
    Contact for pricing
    1,400 SF

    Retail/Office Space in Carencro

    1,400 SF retail or office space in thriving commercial corridor.

    107 Hector Connoly Rd, Carencro, LA 70520
    View details
    Flexible Commercial Space Near I-49
    Contact for pricing
    3,240 SF

    Flexible Commercial Space Near I-49

    Versatile commercial property with office, storage, and warehouse space.

    310 E Gloria Switch Rd, Lafayette, LA 70507
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    Lafayette Commercial Mixed-Use Development
    Contact for pricing
    10,000 SF

    Lafayette Commercial Mixed-Use Development

    New commercial mixed-use retail/office development with build-to-suite options.

    608 E Gloria Switch Rd, Lafayette, LA 70507
    View details

    Opelousas, LA Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Opelousas, LA with 11 listings featured on our commercial real estate exchange. The current inventory includes 1,726,701,044 square feet of properties with an estimated lease value of $1.79 SF/Yr.

    Estimated lease rates for Commercial real estate in Opelousas, LA begin at $1.79 SF/Yr, with an average of $1.79 SF/Yr and extend to $1.79 SF/Yr.
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