Effingham County, IL Commercial Real Estate for Lease

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Junior Anchor Retail Space with Pylon
Updated: Feb 12
Junior Anchor Retail Space with Pylon

1000-1006 N Keller Dr, Effingham, IL 62401

Contact for pricing
10,069 sqft
42,832 SF retail center with available junior anchor space
Junior anchor space available: 10,069 SF
Shadowed by Hobby Lobby with strong tenant adjacency
Pylon signage available
Direct access directly off I‑57
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Medical Office Space with Treatment Rooms
Updated: Aug 26, 2025
Medical Office Space with Treatment Rooms

401 N Keller Dr, Effingham, IL 62401

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2,000 sqft
About 2,000 SF former chiropractic office space
Open reception area with high ceilings
Six treatment rooms
Three treatment rooms with plumbing
Storage room plus back work area
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Large-Scale Manufacturing Facility
Large-Scale Manufacturing Facility

515 W Main St, Teutopolis, IL 62467

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90,000 sqft

Large industrial facility configured for manufacturing, processing, or bulk storage with truck-accessible site and yard use.

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Divisible Flex Space
Divisible Flex Space

110 N Henrietta Street, Effingham, IL 62401

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Space can be divided to accommodate office, retail, or warehouse uses.

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Prime Commercial Outlot Opportunity
Prime Commercial Outlot Opportunity

201 Walk Ave, Effingham, IL 62401

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2 sqft 2.00 AC lot

Available 2-acre outlot near Rural King and major routes.

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Based on your search, we've compiled 20 Potential Opportunities for your consideration. Besides 5 Active listings in Effingham County, IL, we suggest exploring alternatives. Similar 15 Properties for Sales.

Similar Spaces for Sale in Effingham County, IL

Consider Similar Space for Sale. We found 15 Spaces matching your search parameters.

Auto Repair Facility with Lifts
Auto Repair Facility with Lifts

2300 Hoffman Drive, Effingham, IL 62401

$975,000
7,080 sqft 2.52 AC lot

Turnkey auto repair business and real estate with seven lifts, multiple workstations, and a fenced yard on 2.52 acres.

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Medical Condo Office Units
Medical Condo Office Units

401 N Keller Dr, Effingham, IL 62401

$1,200,000
6,000 sqft

Two middle condo suites totaling 6,000 SF, with one vacant and ready for occupancy in an established healthcare-anchored center.

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Insulated Warehouse with Overhead Doors
Insulated Warehouse with Overhead Doors

8913 E 1800th North Avenue, Shumway, IL 62461

$449,900
8,280 sqft 1.76 AC lot

Heated and cooled warehouse with concrete floors, substantial exterior gravel parking, and utility infrastructure suited to commercial operations.

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Cleared Development Land Parcel
Cleared Development Land Parcel

15205 N Siemer Road, Effingham, IL 62401

$849,900
2.16 AC lot

Over 2 acres of land with select tree and brush clearing, offering flexibility for future development in Effingham.

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Automotive Wash With Vacuum Stations
Automotive Wash With Vacuum Stations

1103 W Jefferson Avenue, Effingham, IL 62401

$950,000

Operating automotive wash with vacuum stations, office space, restrooms, and B-2 general commercial zoning.

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Senior Housing Retirement Facility
Senior Housing Retirement Facility

1234 North Main Street, Effingham, IL 62401

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19,500 sqft

For sale senior housing facility with healthcare-oriented use, listed at approximately 19,500 square feet.

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Bar and Grill Restaurant
Bar and Grill Restaurant

112 W Adams Avenue, Altamont, IL 62411

$619,000

Bar and grill with a rented upstairs apartment and a private room for events.

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Auto Shop With Attached Canopy
Auto Shop With Attached Canopy

1001 N Keller Dr, Effingham, IL 62401

$325,000

Former auto service building with an attached canopy, offered in its current as-is condition.

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Commercial Land with Highway Access
Commercial Land with Highway Access

1700 W Fayette Ave, Effingham, IL 62401

$3,500,000

EB-5-zoned commercial land with direct access to the Fayette Avenue corridor.

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Commercial Land with Pond
Commercial Land with Pond

8691 N 300th Street, Altamont, IL 62411

$833,000

AGR-zoned acreage extends alongside I-70, with access to nearby interstate ramps.

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Commercial Land with On/Off Access
Commercial Land with On/Off Access

809 N Keller Drive, Effingham, IL 62401

$645,900

Commercially zoned 2-lot parcel with existing structure on a high-visibility site just off an I-57/I-70 exit.

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Large Industrial Manufacturing Facility
Large Industrial Manufacturing Facility

515 W Main St, Teutopolis, IL 62467

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90,000 sqft

Large-scale industrial facility designed for manufacturing, processing, or bulk storage with truck access and yard use.

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Showroom Building with Detached Garage
Showroom Building with Detached Garage

1704 S Banker St, Effingham, IL 62401

$385,000

Includes office, workspace, breakroom, parking, and two recently installed furnaces.

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Hospital-Adjacent Parking Lot
Hospital-Adjacent Parking Lot

501 Mulberry Street, Effingham, IL 62401

$450,000

Parking asset across from St. Anthony Hospital includes two additional lots to the west.

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Industrial Land with Interstate Access
Industrial Land with Interstate Access

1703 W Evergreen Ave, Effingham, IL 62401

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45.00 AC lot

Three parcels support industrial outdoor storage planning, with subdivision flexibility and an existing income stream associated with Blue Beacon.

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Effingham County, IL Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Effingham County, IL with 5 listings featured on our commercial real estate exchange. The current inventory includes 102,071 square feet of properties.
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