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    Effingham, IL

    Effingham, IL Commercial Real Estate for Lease

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    Teutopolis, IL
    Junior Anchor Retail Space with Pylon
    Updated: Feb 12
    Junior Anchor Retail Space with Pylon

    1000-1006 N Keller Dr, Effingham, IL 62401

    Contact for pricing
    10,069 sqft
    42,832 SF retail center with available junior anchor space
    Junior anchor space available: 10,069 SF
    Shadowed by Hobby Lobby with strong tenant adjacency
    Pylon signage available
    Direct access directly off I‑57
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    Medical Office Space with Treatment Rooms
    Updated: Aug 26, 2025
    Medical Office Space with Treatment Rooms

    401 N Keller Dr, Effingham, IL 62401

    Contact for pricing
    2,000 sqft
    About 2,000 SF former chiropractic office space
    Open reception area with high ceilings
    Six treatment rooms
    Three treatment rooms with plumbing
    Storage room plus back work area
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    Divisible Flex Space
    Divisible Flex Space

    110 N Henrietta Street, Effingham, IL 62401

    Contact for pricing

    Space can be divided to accommodate office, retail, or warehouse uses.

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    Prime Commercial Outlot Opportunity
    Prime Commercial Outlot Opportunity

    201 Walk Ave, Effingham, IL 62401

    Contact for pricing
    2 sqft 2.00 AC lot

    Available 2-acre outlot near Rural King and major routes.

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    Based on your search, we've compiled 19 Potential Opportunities for your consideration. Besides 4 Active listings in Effingham, IL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 11 Properties for Sales.

    Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Large-Scale Manufacturing Facility
    Large-Scale Manufacturing Facility

    515 W Main St, Teutopolis, IL 62467

    Contact for pricing
    90,000 sqft

    Large industrial facility configured for manufacturing, processing, or bulk storage with truck-accessible site and yard use.

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    Industrial Warehouse with 16'–22' Clear Height
    Industrial Warehouse with 16'–22' Clear Height

    1501 S 19th St, Mattoon, IL 61938

    Contact for pricing
    166,928 sqft

    Industrial and office space with 16'–22'4" clear heights and several overhead doors, with rail possible nearby.

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    Retail Space Near Lake Land
    Retail Space Near Lake Land

    1510-1532 Lake Land Blvd, Mattoon, IL

    Contact for pricing
    1,475 sqft 2.02 AC lot

    Retail spaces available near Lake Land College and I-57.

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    Land for Retail, Restaurant, Hotel
    Land for Retail, Restaurant, Hotel

    1017 Remington Rd, Mattoon, IL

    Contact for pricing
    2.42 AC lot

    Land available for retail, restaurant, and hotel development.

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    Similar Spaces for Sale in Effingham, IL

    Consider Similar Space for Sale. We found 11 Spaces matching your search parameters.

    Auto Repair Facility with Lifts
    Auto Repair Facility with Lifts

    2300 Hoffman Drive, Effingham, IL 62401

    $975,000
    7,080 sqft 2.52 AC lot

    Turnkey auto repair business and real estate with seven lifts, multiple workstations, and a fenced yard on 2.52 acres.

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    Medical Condo Office Units
    Medical Condo Office Units

    401 N Keller Dr, Effingham, IL 62401

    $1,200,000
    6,000 sqft

    Two middle condo suites totaling 6,000 SF, with one vacant and ready for occupancy in an established healthcare-anchored center.

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    Cleared Development Land Parcel
    Cleared Development Land Parcel

    15205 N Siemer Road, Effingham, IL 62401

    $849,900
    2.16 AC lot

    Over 2 acres of land with select tree and brush clearing, offering flexibility for future development in Effingham.

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    Automotive Wash With Vacuum Stations
    Automotive Wash With Vacuum Stations

    1103 W Jefferson Avenue, Effingham, IL 62401

    $950,000

    Operating automotive wash with vacuum stations, office space, restrooms, and B-2 general commercial zoning.

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    Senior Housing Retirement Facility
    Senior Housing Retirement Facility

    1234 North Main Street, Effingham, IL 62401

    Contact for pricing
    19,500 sqft

    For sale senior housing facility with healthcare-oriented use, listed at approximately 19,500 square feet.

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    Auto Shop With Attached Canopy
    Auto Shop With Attached Canopy

    1001 N Keller Dr, Effingham, IL 62401

    $325,000

    Former auto service building with an attached canopy, offered in its current as-is condition.

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    Commercial Land with Highway Access
    Commercial Land with Highway Access

    1700 W Fayette Ave, Effingham, IL 62401

    $3,500,000

    EB-5-zoned commercial land with direct access to the Fayette Avenue corridor.

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    Commercial Land with On/Off Access
    Commercial Land with On/Off Access

    809 N Keller Drive, Effingham, IL 62401

    $645,900

    Commercially zoned 2-lot parcel with existing structure on a high-visibility site just off an I-57/I-70 exit.

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    Showroom Building with Detached Garage
    Showroom Building with Detached Garage

    1704 S Banker St, Effingham, IL 62401

    $385,000

    Includes office, workspace, breakroom, parking, and two recently installed furnaces.

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    Hospital-Adjacent Parking Lot
    Hospital-Adjacent Parking Lot

    501 Mulberry Street, Effingham, IL 62401

    $450,000

    Parking asset across from St. Anthony Hospital includes two additional lots to the west.

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    Industrial Land with Interstate Access
    Industrial Land with Interstate Access

    1703 W Evergreen Ave, Effingham, IL 62401

    Contact for pricing
    45.00 AC lot

    Three parcels support industrial outdoor storage planning, with subdivision flexibility and an existing income stream associated with Blue Beacon.

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    Effingham, IL Commercial real estate Market Trends and Statistics

    Explore Commercial real estate leasing options in Effingham, IL with 4 listings featured on our commercial real estate exchange. The current inventory includes 12,071 square feet of properties.
    Effingham, IL CRE market trends — vacancy, lease rates and price per SF, updated monthly
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