De Soto, IA Commercial Real Estate for Lease

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Retail Space in Growing Suburb
Updated: Nov 22, 2025
Retail Space in Growing Suburb

1202 Guthrie Street, De Soto, IA 50069

$28 SF/Yr
11,250 sqft
High accessibility due to strategic location just south of Exit 110 on I‑80 and Hwy 169.
Located in the growing western suburb of De Soto.
New retail shopping center development.
Total of 11,250 square feet available.
Six bays, each 25' x 75'.
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Based on your search, we've compiled 12 Potential Opportunities for your consideration. Besides 1 Active listings in De Soto, IA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 7 Properties for Sales.

Commercial real estate for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Waukee Flex Space Available
Waukee Flex Space Available

33083 Ute Avenue, Waukee, IA 50263

$11.50 SF/Yr
12,155 sqft

Flex space in high-growth Waukee corridor with I-80 access.

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Flexible Space in Adel, Iowa
Flexible Space in Adel, Iowa

26416 289th Pl, Adel, IA 50003

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6,000 sqft

Divisible flex spaces with overhead doors and HVAC for rent.

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Warehouse For Lease
Warehouse For Lease

26378 289th Pl, Adel, IA 50003

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Warehouse positioned on Highway 6 near Interstate 80 with adjacency to the upcoming Apple data center site.

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Retail Space Near Waukee Northwest
Retail Space Near Waukee Northwest

750 US-6, Waukee, IA 50263

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Retail space for lease near Waukee Northwest High School.

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Similar Spaces for Sale in De Soto, IA

Consider Similar Space for Sale. We found 7 Spaces matching your search parameters.

Agricultural Timber Tract with Tillable Acres
Agricultural Timber Tract with Tillable Acres

23716 360th Street, De Soto, IA 50069

$7,561,350
504.00 AC lot

Zoned AG farmland featuring approximately 200 acres of productive tillable ground and extensive heavy timber.

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Agricultural Land Along Interstate 80
Agricultural Land Along Interstate 80

24553 347th St, De Soto, IA 50069

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321 sqft 321.01 AC lot

Large agricultural tract with Agriculture zoning and direct Interstate 80 frontage.

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Agricultural Land with Forest Reserve Program
Agricultural Land with Forest Reserve Program

W Adjacent to 23152 347th Street, De Soto, IA 50069

$1,160,000
41.50 AC lot

Zoned AG and served by public water, with part of the acreage enrolled in the Forest Reserve Program.

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Industrial Specialty Building
Industrial Specialty Building

25 Ellefson Dr, De Soto, IA 50069

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4,800 sqft

Specialty industrial property offered for sale with 4,800 SF of space.

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AG-Zoned Agricultural Land
AG-Zoned Agricultural Land

E & W Adjacent to 23152 347th Street, De Soto, IA 50069

$760,000
27.24 AC lot

For sale 27.24-acre parcel zoned AG in De Soto, IA.

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Commercial Land I-80 Frontage
Commercial Land I-80 Frontage

Ash St, De Soto, IA

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7.17 AC lot

Commercial land with I-80 frontage in growing suburb.

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235 Acres of Agricultural Land
235 Acres of Agricultural Land

I-80 & 169 Highway, De Soto, IA 50003

$11,500,000
235.00 AC lot

235 acres of agricultural land for sale in De Soto.

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De Soto, IA Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in De Soto, IA with 1 listings featured on our commercial real estate exchange. The current inventory includes 11,250 square feet of properties with an estimated lease value of $28.

Estimated lease rates for Commercial real estate in De Soto, IA average $28 SF/Yr.
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