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    Santa Cruz County, CA Commercial Real Estate for Lease

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    Los Angeles, CA San Diego, CA San Francisco, CA
    111 results
    Retail Space in Santa Cruz
    $4,500 /Mo
    1,500 SF

    Retail Space in Santa Cruz

    805 Ocean ST 815, Santa Cruz, CA 95060

    High-visibility retail location with significant traffic in Santa Cruz.

    • High visibility retail location at major intersection of Ocean St. and Water St.
    • High traffic count: over 20,000 cars pass per day.
    • Adjacent to Santa Cruz County Center.
    • Parking available.
    • Wheelchair accessible with ramp.
    Updated: Feb 6
    View details
    Medical Office in Watsonville
    $0.12 SF/Yr
    4,422 SF

    Medical Office in Watsonville

    60 Penny Ln, Watsonville, CA

    Two-story medical office building in Watsonville's commercial district.

    • High‑visibility location in Watsonville's commercial‑medical district.
    • 4422 sqft+\/- medical‑office building in excellent condition.
    • Multiple private office/exam treatment rooms and large open floor plan.
    • Ample parking and walkability to amenities (dining, shops, gym, bus line).
    • Two private bathrooms with laundry and shower access.
    Updated: Nov 7, 2025
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    Class A Office Building
    $4 SF/Yr
    6,281 SF

    Class A Office Building

    Professional office building near downtown Los Gatos and Vasona Park.

    720 University Avenue, Los Gatos, CA 95032
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    Santa Cruz Office Space Available
    $2,668 /Mo
    2,668 SF

    Santa Cruz Office Space Available

    Office space available for rent in Santa Cruz, CA.

    133 Mission St, Suite 210, Santa Cruz, CA 95060
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    Downtown Santa Cruz Retail Space
    $42 SF/Yr
    1,022 SF

    Downtown Santa Cruz Retail Space

    Retail spaces in a new apartment complex, available now.

    525 Cedar St, Santa Cruz, CA 95060
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    Retail Space on Capitola Road
    $2 SF/Yr
    7,725 SF

    Retail Space on Capitola Road

    Divisible retail space available now on 41st and Capitola.

    4150 Capitola Rd, Capitola, CA
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    Downtown Retail Space Available
    $15 SF/Yr
    3,500 SF

    Downtown Retail Space Available

    Retail space in a vibrant downtown location on Pacific Avenue.

    1115-1117 Pacific Ave, Santa Cruz, CA
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    Retail Space in New Complex
    $1.25 SF/Yr
    965 SF

    Retail Space in New Complex

    Retail storefronts in a high-traffic, walkable Santa Cruz location.

    350 Ocean St, Santa Cruz, CA
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    Santa Cruz Office Space Available
    $1,852 /Mo
    805 SF

    Santa Cruz Office Space Available

    Office space for rent in a desirable Santa Cruz location.

    700-704 Soquel Ave, Santa Cruz, CA
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    Office Space in Scotts Valley
    $18 SF/Yr
    8,210 SF

    Office Space in Scotts Valley

    Ground floor office space with extensive glass line and free parking.

    5615-5619 Scotts Valley Dr, Scotts Valley, CA
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    Santa Cruz Office Space Available
    $1.40 SF/Yr
    1,976 SF

    Santa Cruz Office Space Available

    Office space for rent in a desirable Santa Cruz location.

    207 McPherson St, Santa Cruz, CA
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    Live Oak Commercial Office Space
    $1.50 SF/Yr
    2,100 SF

    Live Oak Commercial Office Space

    2,100 SF office space in residential Live Oak.

    2215 7th Ave, Santa Cruz, CA
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    Soquel Office/Creative Space For Rent
    $2,000 /Mo
    686 SF

    Soquel Office/Creative Space For Rent

    Second floor office or creative space near Cabrillo College.

    2955 Park Ave, Soquel, CA
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    Ground Floor Commercial Space Available
    $1.70 SF/Yr
    4,430 SF

    Ground Floor Commercial Space Available

    Commercial space for lease, formerly a bank, with ample parking.

    3001 Thurber Ln, Santa Cruz, CA
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    Los Gatos Retail/Office Space
    $42 SF/Yr
    533 SF

    Los Gatos Retail/Office Space

    Ground floor suite available now in prime Los Gatos location.

    634 N Santa Cruz Ave, Los Gatos, CA
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    Aptos Former Bank Space
    $30 SF/Yr
    3,500 SF

    Aptos Former Bank Space

    Approximately 3,500 SF space with mezzanine office for rent.

    783 Rio Del Mar Blvd, Aptos, CA
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    Los Gatos Office Space Available
    $39 SF/Yr
    2,850 SF

    Los Gatos Office Space Available

    Corner office unit with excellent glass line and rear loading.

    761 University Ave, Los Gatos, CA
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    Santa Cruz Office Space Available
    $2 SF/Yr
    768 SF

    Santa Cruz Office Space Available

    Office space for rent in prime Santa Cruz location.

    1667 Dominican Way, Santa Cruz, CA
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    Aptos Office Space Available
    $2 SF/Yr
    1,100 SF

    Aptos Office Space Available

    Office space featuring a reception area, kitchenette, and conference room.

    7010 Soquel Dr, Aptos, CA
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    Los Gatos Office Space Available
    $3 SF/Yr
    7,009 SF

    Los Gatos Office Space Available

    New office space with open configuration and specialized medtech facilities.

    140-162 Knowles Dr, Los Gatos, CA
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    Los Gatos Office Space Available
    $47 SF/Yr
    2,179 SF

    Los Gatos Office Space Available

    Professional office park in a premier west valley location.

    16615 Lark Ave, Los Gatos, CA
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    Santa Cruz Office Space Available
    $15 SF/Yr
    6,250 SF

    Santa Cruz Office Space Available

    Office space for rent in Santa Cruz, California.

    1121 Pacific Ave, Santa Cruz, CA
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    Class A+ Office Space Available
    $28 SF/Yr
    11,999 SF

    Class A+ Office Space Available

    High-quality office space with amenities in Scotts Valley, CA.

    100 Enterprise Way, Scotts Valley, CA
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    Retail Space in Watsonville
    $12 SF/Yr
    3,029 SF

    Retail Space in Watsonville

    Retail space available for lease in Watsonville, California.

    1200 Main St, Watsonville, CA
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    Santa Cruz County, CA Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Santa Cruz County, CA with 111 listings featured on our commercial real estate exchange. The current inventory includes 2,034,818,280 square feet of properties with an estimated lease value of $158 SF/Yr.

    Estimated lease rates for Commercial real estate in Santa Cruz County, CA begin at $1.25 SF/Yr, with an average of $10 SF/Yr and extend to $47 SF/Yr.
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