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Santa Cruz County, CA Commercial Real Estate for Lease

114 results
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Retail Space in Santa Cruz
$4,500 / Mo
1,500 SF

Retail Space in Santa Cruz

805 Ocean St, Santa Cruz, CA 95060

High-visibility retail location with significant traffic in Santa Cruz.

  • High visibility retail location at major intersection of Ocean St. and Water St.
  • High traffic count: over 20,000 cars pass per day.
  • Adjacent to Santa Cruz County Center.
  • Parking available.
  • Wheelchair accessible with ramp.
Updated: Feb 6
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Downtown Santa Cruz Office Building
$4,000 / Mo
2,060 SF

Downtown Santa Cruz Office Building

129 Water St, Santa Cruz, CA 95060

Freestanding commercial office building in the heart of downtown Santa Cruz.

  • Freestanding commercial office building in the heart of downtown Santa Cruz.
  • Move‑in ready condition for owner‑occupant or tenant.
  • 10 offices, 2 conference rooms, and a large reception area.
  • Modern infrastructure with controlled door access, security cameras, and prominent street signage.
  • 4 on‑site parking spaces and excellent walkability to downtown amenities.
Updated: Oct 6, 2025
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Soquel Office/Creative Space For Rent
$2,000 / Mo
686 SF

Soquel Office/Creative Space For Rent

Second floor office or creative space near Cabrillo College.

2955 Park Ave, Soquel, CA 95073
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Medical Office in Watsonville
$1.53 SF/Yr
4,422 SF

Medical Office in Watsonville

Two-story medical office building in Watsonville's commercial district.

60 Penny Ln, Watsonville, CA 95076
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Santa Cruz Office Space Available
$1.55 SF/Yr
9,000 SF

Santa Cruz Office Space Available

Highly visible office space for lease in Santa Cruz.

2880 Soquel Ave, Santa Cruz, CA 95062
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Los Gatos Retail Space Available
$3 SF/Yr
2,300 SF

Los Gatos Retail Space Available

Retail space in Los Gatos with private parking.

26-32 E Main St, Los Gatos, CA 95030
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Los Gatos Retail Space Available
Contact for pricing

Los Gatos Retail Space Available

Trader Joe's anchored shopping center with restaurant opportunity.

15466 Los Gatos Blvd, Los Gatos, CA 95032
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Renovated Office Space in Scotts
Contact for pricing
2,500 SF

Renovated Office Space in Scotts

2500 sq ft office space with high ceilings.

5011 Scotts Valley Dr, Scotts Valley, CA 95066
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Los Gatos Retail Space
Contact for pricing
1,025 SF

Los Gatos Retail Space

Retail space in prime Silicon Valley location.

23 University Ave, Los Gatos, CA 95030
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Live Oak Commercial Office Space
$1.50 SF/Yr
2,100 SF

Live Oak Commercial Office Space

2,100 SF office space in residential Live Oak.

2215 7Th Ave, Santa Cruz, CA 95062
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Grocery Anchored Shopping Center Space
Contact for pricing
74,199 SF

Grocery Anchored Shopping Center Space

Retail spaces available in a busy, grocery-anchored shopping center.

15521 Union Ave, Los Gatos, CA 95032
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Los Gatos Restaurant Opportunity
Contact for pricing
2,307 SF

Los Gatos Restaurant Opportunity

Second generation restaurant space with dedicated parking and signage.

16150 Los Gatos Blvd, Los Gatos, CA 95032
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Second Story Office Suites For Rent
$1.85 SF/Yr
484 SF

Second Story Office Suites For Rent

Second story office suites with high ceilings and natural light.

1205 Pacific Ave, Santa Cruz, CA 95060
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Retail Space in New Complex
$1.25 SF/Yr
965 SF

Retail Space in New Complex

Retail storefronts in a high-traffic, walkable Santa Cruz location.

350 Ocean St, Santa Cruz, CA 95060
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Los Gatos Retail Opportunity
Contact for pricing
1,000 SF

Los Gatos Retail Opportunity

Modern retail space with access to downtown and Highway 17.

53 Los Gatos Saratoga Rd, Los Gatos, CA 95032
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Retail Space in Desirable Location
$47 SF/Yr
3,070 SF

Retail Space in Desirable Location

Retail space with ample parking and close to amenities.

1415-1491 Main St, Watsonville, CA 95076
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Professional Office Space Available
$2.00 SF/Yr
555 SF

Professional Office Space Available

Well-maintained office building with separately metered suites for rent.

5321 Scotts Valley Dr, Scotts Valley, CA 95066
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Downtown Santa Cruz Office Space
$1.65 SF/Yr
1,170 SF

Downtown Santa Cruz Office Space

Class A office suites available for rent in downtown Santa Cruz.

133 Mission St, Santa Cruz, CA 95060
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Santa Cruz Office Space Available
$2 SF/Yr
768 SF

Santa Cruz Office Space Available

Office space for rent in prime Santa Cruz location.

1667 Dominican Way, Santa Cruz, CA 95065
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Santa Cruz Office Space Available
$1.40 SF/Yr
1,976 SF

Santa Cruz Office Space Available

Office space for rent in a desirable Santa Cruz location.

207 Mcpherson St, Santa Cruz, CA 95060
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Santa Cruz Office Space Available
Contact for pricing
950 SF

Santa Cruz Office Space Available

950 SF office space with ample parking in Santa Cruz.

550 Water St, Santa Cruz, CA 95060
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Los Gatos Retail Space
Contact for pricing
1,682 SF

Los Gatos Retail Space

Retail space available for lease in Los Gatos, CA.

708-798 Blossom Hill Rd, Los Gatos, CA 95032
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Retail Space in Scotts Valley
Contact for pricing
1,811 SF

Retail Space in Scotts Valley

Retail space available for lease in Scotts Valley, CA.

260-266 Mount Hermon Rd, Scotts Valley, CA 95066
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Los Gatos Retail Opportunity
Contact for pricing
1,756 SF

Los Gatos Retail Opportunity

New retail and restaurant spaces in Los Gatos village.

15500 Ml St, Los Gatos, CA
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Santa Cruz County, CA Commercial real estate Leasing Opportunities Market Analysis

Explore Commercial real estate leasing options in Santa Cruz County, CA with 221 listings featured on our commercial real estate exchange. The current inventory includes 6,232,259,880 square feet of properties with an estimated lease value of $371 /Mo.

Estimated lease rates for Commercial real estate in Santa Cruz County, CA begin at $1.25 SF/Yr, with an average of $14 SF/Yr and extend to $48 SF/Yr.
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