Sign Up Successful!
You now have access to more from Realmo!
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Space Uses
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Santa Cruz, CA Commercial Real Estate for Lease

    48 results
    List
    Map
    Downtown Santa Cruz Office Building
    $4,000 / Mo
    2,060 SF

    Downtown Santa Cruz Office Building

    129 Water St, Santa Cruz, CA 95060

    Freestanding commercial office building in the heart of downtown Santa Cruz.

    • Freestanding commercial office building in the heart of downtown Santa Cruz.
    • Move‑in ready condition for owner‑occupant or tenant.
    • 10 offices, 2 conference rooms, and a large reception area.
    • Modern infrastructure with controlled door access, security cameras, and prominent street signage.
    • 4 on‑site parking spaces and excellent walkability to downtown amenities.
    Updated: Oct 6, 2025
    View details
    Commercial Space in Santa Cruz
    $2,495 / Mo
    4,000 SF

    Commercial Space in Santa Cruz

    2017 Pacific Ave, Santa Cruz, CA 95060

    Retail space for lease in Santa Cruz, California.

    • Unique location
    • Good size for most businesses
    • Recently painted inside and out
    • Big windows
    • New flooring to be installed
    Updated: Nov 13, 2025
    View details
    Retail/Office Space in Santa Cruz
    $2,500 / Mo
    3,135 SF

    Retail/Office Space in Santa Cruz

    3135 SF retail or office space available for rent.

    Cooper St, Santa Cruz, CA 95060
    View details
    Santa Cruz Warehouse - 13,200 SF
    $15 SF/Yr
    13,200 SF

    Santa Cruz Warehouse - 13,200 SF

    Large Santa Cruz warehouse, ample parking.

    2450 17Th Ave, Santa Cruz, CA 95062
    View details
    Mission Drive Medical Office
    $33 SF/Yr
    2,676 SF

    Mission Drive Medical Office

    Santa Cruz medical office space available.

    3321 Mission Dr, Santa Cruz, CA 95065
    View details
    Santa Cruz Restaurant - Lease Opportunity
    $24 SF/Yr
    18,809 SF

    Santa Cruz Restaurant - Lease Opportunity

    Historic Santa Cruz Restaurant Space Available

    555 Soquel Ave, Santa Cruz, CA 95062
    View details
    Santa Cruz Office Space for Lease
    $18 SF/Yr
    11,826 SF

    Santa Cruz Office Space for Lease

    Prime Santa Cruz Office, 742 sq ft.

    501 Mission St, Santa Cruz, CA 95060
    View details
    Santa Cruz Office Suites for Lease
    $20 SF/Yr
    7,000 SF

    Santa Cruz Office Suites for Lease

    Prime Santa Cruz location, flexible office spaces.

    542 Ocean St, Santa Cruz, CA 95060
    View details
    Linda Vista Shopping Center: Prime Retail Space
    $48 SF/Yr
    15,000 SF

    Linda Vista Shopping Center: Prime Retail Space

    Westside Santa Cruz retail center, 8 suites, space available.

    2320 Mission St, Santa Cruz, CA 95060
    View details
    West Side Santa Cruz Flex Space
    $1.15 SF/Yr
    6,800 SF

    West Side Santa Cruz Flex Space

    Vibrant retail/industrial area with flexible office and open floorplans.

    2125 Delaware Ave, Santa Cruz, CA 95060
    View details
    Downtown Santa Cruz Retail Space
    $3 SF/Yr
    4,622 SF

    Downtown Santa Cruz Retail Space

    New retail space in mixed-use building, prime downtown location.

    800 Pacific Ave, Santa Cruz, CA 95060
    View details
    Ground Floor Commercial Space Available
    $1.70 SF/Yr
    4,430 SF

    Ground Floor Commercial Space Available

    Commercial space for lease, formerly a bank, with ample parking.

    3001 Thurber Ln, Santa Cruz, CA 95065
    View details
    Mixed-Use Development Retail Space
    Contact for pricing
    1,744 SF

    Mixed-Use Development Retail Space

    Retail space in a mixed-use development with residential units.

    418-508 Front St, Santa Cruz, CA 95060
    View details
    Live Oak Commercial Office Space
    $1.50 SF/Yr
    2,100 SF

    Live Oak Commercial Office Space

    2,100 SF office space in residential Live Oak.

    2215 7Th Ave, Santa Cruz, CA 95062
    View details
    Santa Cruz Office Space Available
    $1,852 / Mo
    805 SF

    Santa Cruz Office Space Available

    Office space for rent in a desirable Santa Cruz location.

    700-704 Soquel Ave, Santa Cruz, CA 95062
    View details
    Furnished Office Space in Santa Cruz
    $2 SF/Yr
    12,182 SF

    Furnished Office Space in Santa Cruz

    High-end, fully furnished office space in premier city center location.

    1349-1395 Pacific Ave, Santa Cruz, CA 95060
    View details
    Renovated Office Space Available
    $850 / Mo
    559 SF

    Renovated Office Space Available

    Newly renovated office suites with elevator access, natural light.

    903 Pacific Ave, Santa Cruz, CA 95060
    View details
    Downtown Santa Cruz Office Space
    $1.65 SF/Yr
    1,170 SF

    Downtown Santa Cruz Office Space

    Class A office suites available for rent in downtown Santa Cruz.

    133 Mission St, Santa Cruz, CA 95060
    View details
    Retail Space on Soquel Avenue
    Contact for pricing
    671 SF

    Retail Space on Soquel Avenue

    Retail space available for lease on Soquel Avenue.

    2112-2128 Soquel Ave, Santa Cruz, CA 95062
    View details
    Retail Space in Santa Cruz
    $22 SF/Yr
    1,014 SF

    Retail Space in Santa Cruz

    Retail space available for lease in Santa Cruz, CA.

    333-381 Soquel Ave, Santa Cruz, CA 95062
    View details
    Renovated Retail Space, Former Bank
    $39 SF/Yr

    Renovated Retail Space, Former Bank

    Renovated retail space, previously a Bank of America branch.

    1128-1134 Pacific Ave #1130, Santa Cruz, CA 95060
    View details
    Westside Santa Cruz Flex Space
    $1.90 SF/Yr
    9,251 SF

    Westside Santa Cruz Flex Space

    9,251 SF flex space in thriving Westside Santa Cruz.

    2161 Delaware Ave, Santa Cruz, CA 95060
    View details
    Prime Retail Space in Santa Cruz
    $39 SF/Yr
    11,077 SF

    Prime Retail Space in Santa Cruz

    Historic building with ample parking in a central location.

    1132-1134 Pacific Ave, Santa Cruz, CA 95060
    View details
    Retail Space in Mixed-Use Property
    Contact for pricing
    2,682 SF

    Retail Space in Mixed-Use Property

    Retail space available in mixed-use property with residential units.

    150 Chestnut St, Santa Cruz, CA 95060
    View details

    Santa Cruz, CA Commercial Real Estate Leasing Opportunities Market Analysis

    Explore Commercial Real Estate leasing options in Santa Cruz, CA with 72 listings featured on our commercial real estate exchange. The current inventory includes 7,391,609,280 square feet of properties with an estimated lease value of $487 /Mo.

    Estimated lease rates for Commercial Real Estate in Santa Cruz, CA begin at $1.15 SF/Yr, with an average of $13 SF/Yr and extend to $48 SF/Yr.

    In Santa Cruz, CA, current lease rates show:

    • Office Properties & Spaces positioned at $9
    • Office space measuring $6
    • Retail properties assessed at $18
    • Individual retail properties calculated at $15
    List
    Map

    Browse Commercial real estate for Lease Near Santa Cruz, CA

    Popular Searches in Santa Cruz, CA

    Most Searched ZIP Codes in Santa Cruz, CA

    • 95060
    • 95062
    • 95065
    • 92701
    • 95017

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Create New Password
    • At least 8 characters
    • Contains both letters and numbers
    • Contains uppercase and lowercase letters
    • At most 32 characters
    • Password required
    • Password reset link has expired. Please request a new one.