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    Oconee County, SC Retail Space for Lease

    6 results
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    Downtown Seneca Commercial Space Available
    $2,700 / Mo

    Downtown Seneca Commercial Space Available

    104 North 1St St, Seneca, SC 29678

    Commercial space for rent in downtown Seneca with street frontage.

    • Great frontage on the main drag
    • Ideal for many uses
    • Downtown Seneca location
    • Plenty of free public parking just around the corner
    • $2700/month rent
    Updated: Oct 11, 2025
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    Applewood Shopping Center Opportunity
    Contact for pricing
    244,693 SF

    Applewood Shopping Center Opportunity

    201 Applewood Center Pl, Seneca, SC 29678

    High-traffic retail center near Clemson University

    • High‑visibility retail space directly across from the 169‑bed Oconee Medical Center.
    • Less than 10 miles from Clemson University.
    • Exceptional daily traffic counts of 18,100 vehicles on US‑76/Sandifer Blvd.
    • 244,693 total square feet.
    • Multiple tenancies available, with spaces ranging from 1,000 to 16,000 contiguous square feet.
    Updated: Dec 11, 2024
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    Retail Space Near Clemson University
    $21 SF/Yr
    43,000 SF

    Retail Space Near Clemson University

    End-cap retail space with drive-thru potential near Clemson University.

    1085 Old Clemson Hwy, Seneca, SC 29672
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    Retail Space Near Oconee Medical
    Contact for pricing
    1,600 SF

    Retail Space Near Oconee Medical

    Retail space available near Oconee Medical Center and Clemson University.

    101 Applewood Center Pl, Seneca, SC 29678
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    Seneca Office/Retail Space Available
    $15 SF/Yr
    4,800 SF

    Seneca Office/Retail Space Available

    Office and retail spaces for lease in Seneca, South Carolina.

    12019 North Radio Station Rd, Seneca, SC 29678
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    Retail Opportunity Near Walmart
    Contact for pricing

    Retail Opportunity Near Walmart

    Retail space available for lease, GL, or build-to-suit.

    1637 Sandifer Blvd, Seneca, SC 29678
    View details
    Based on your search, we've compiled 14 Potential Opportunities for your consideration. Besides 6 Active listings in Oconee County, SC, we suggest exploring alternatives. Similar 8 Properties for Sales.

    Explore Similar Spaces for Sale in Oconee County, SC

    Consider Similar Space for Sale. We found 8 Spaces in Nearby Locations matching your search parameters.

    Charming Commercial Building on Highway 123
    $195,000

    Charming Commercial Building on Highway 123

    Retail or restaurant opportunity on high-traffic Highway 123 in Westminster.

    3518 Toccoa Hwy, Westminster, SC 29693
    View details
    Historical Brick Building in Seneca
    $999,949

    Historical Brick Building in Seneca

    Three-level, 15,600 SF building in Seneca's Opportunity Zone.

    235 Main St, Seneca, SC 29678
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    Walhalla Retail Property For Sale
    $499,900
    4,000 SF

    Walhalla Retail Property For Sale

    Prime retail property in Walhalla with income-producing potential.

    104 W Main St, Walhalla, SC 29691
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    Westminster Commercial Space For Sale
    $142,500
    1,148 SF

    Westminster Commercial Space For Sale

    Versatile commercial space in high-traffic location, ready for your vision.

    111 Retreat St, Westminster, SC 29693
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    Highway Frontage Commercial Property
    $175,000
    1.10 Acres

    Highway Frontage Commercial Property

    Commercial property with high visibility and traffic exposure on 1.1 acres.

    810 Sportin Life Ln, Westminster, SC 29693
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    Historic Retail Buildings on Main
    $1,300,000
    6,130 SF

    Historic Retail Buildings on Main

    Renovated retail spaces with historic charm and modern amenities.

    214-218 E Main St, Walhalla, SC 29691
    View details
    Walhalla Main Street Multi-Tenant
    $1,300,000
    6,130 SF

    Walhalla Main Street Multi-Tenant

    Prime Retail Investment, Downtown Walhalla

    212 Main St, Walhalla, SC 29691
    View details
    Downtown Walhalla Mixed-Use Gem
    $875,000
    16,515 SF

    Downtown Walhalla Mixed-Use Gem

    16,515 SF, Vacant, Redevelopment Opportunity

    222 Main St, Walhalla, SC 29691
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    Oconee County, SC Retail space Leasing Opportunities Market Analysis

    Explore Retail space leasing options in Oconee County, SC with 14 listings featured on our commercial real estate exchange. The current inventory includes 12,754,368,000 square feet of properties with an estimated lease value of $58 SF/Yr.

    Estimated lease rates for Retail space in Oconee County, SC begin at $15 SF/Yr, with an average of $19 SF/Yr and extend to $22 SF/Yr.
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    Browse Retail space for Lease Near Oconee, SC

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