Middleton, MA Retail properties & Spaces for Rent & Lease

Updated: Nov 28, 2025

Retail/Office/Medical Space in Middleton

251 South Main Street F, Middleton, MA 01949

$18 SF/Yr

13,524 sqft

High‑traffic location on Rt. 114 with excellent window visibility and marquee signage availability (24K+ cars/day).
Flexible lease terms: base rent plus utilities and dumpster fee; no NNN or CAM.
Located in a highly trafficked plaza anchored by Best Bagel with 50+ parking spaces.
Landlord welcomes all use types: retail, office, or medical.
Strong demographics and location in a high‑income suburb (Middleton) in the Masconomet School District.

View details

Updated: Aug 17

Retail Suite with Treatment Rooms

221 South Main Street, Middleton, MA 01949

Contact for pricing

1,820 sqft

Approximately 1,820 SF of built‑out retail and service space
Direct frontage on Route 114, also known as South Main Street
Traffic counts exceeding 30,000 vehicles per day
Reception area, waiting area, multiple private treatment rooms, and two bathrooms
Established center with Starbucks, Salem Five Bank, and Btone Fitness

View details

Mixed-Use Development with Drive-Thru

49 South Main St, Middleton, MA 01949

Contact for pricing

Ground lease or build-to-suit options with drive-thru and flexible building sizes within a new mixed-use development.

View details

Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center

Established Hair Salon For Sale

227 Maple St, Middleton, MA 01949

$1,800/Mo

0.57 AC lot

Retail space featuring a fully equipped hair salon.

View details

Based on your search, we've compiled 13 Potential Opportunities for your consideration. Besides 4 Active listings in Middleton, MA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 4 Properties for Sales.

Retail properties & Spaces for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

End Unit Box Retail Storefront

A-47 Newbury St, Peabody, MA 01960

$5,500/Mo

1,860 sqft

End unit retail space in a newer building with about 15-foot ceilings, hardwood floors, and on-site parking.

View details

Corner Retail Suite with Private Restrooms

112-435 Newbury St, Danvers, MA 01923

$4,234/Mo

2,540 sqft

Street-level space in a fully accessible plaza along Route 1.

View details

End-Unit Retail Space

C-47 Newbury St, Peabody, MA 01960

$35 SF/Yr

3,720 sqft

Open-concept storefront with on-site parking, private kitchenette, two bathrooms, and prominent Route 1 North exposure.

View details

Retail Space in Danvers Plaza

301 Newbury St, Danvers, MA

Contact for pricing

6,480 sqft 14.91 AC lot

Retail space for lease in supermarket-anchored Danvers Plaza.

View details

Similar Spaces for Sale in Middleton, MA

Consider Similar Space for Sale. We found 4 Spaces matching your search parameters.

Liquor Storefront and Business

21 South Main, Middleton, MA 01949

$1,495,000

2,160 sqft

Established retail liquor operation conveys with the real estate and applicable business licenses.

View details

Retail Space with Treatment Rooms

221 South Main St, Middleton, MA 01949

Contact for pricing

1,820 sqft

Built-out commercial suite with reception, private rooms, customer parking, and pylon signage availability.

View details

Retail Space with High Traffic Exposure

248 S. Main St., Middleton, MA 01949

Contact for pricing

1,100 sqft

Retail space along Route 114 near McDonald’s, Walgreens, Market Basket, and Dairy Queen.

View details

Retail Space with Salon Buildout

227 Maple St, Middleton, MA 01949

Contact for pricing

Existing salon configuration includes customer service areas, support amenities, and a front-facing signage opportunity.

View details

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Versatile Lot for Lease

25 Webster St, Brookline, MA 02446

$8,000/Mo

0.22 AC lot

9,627 sq ft lot suitable for various commercial uses.

View details

Middleton, MA Retail properties & Spaces Lease Rates & Market Statistics

Browse 4 Retail properties & Spaces for lease in Middleton, MA on Realmo, a commercial real estate marketplace serving the Middleton area. The current inventory totals 15,344 square feet of properties.

Retail properties & Spaces lease rates in Middleton range from $18 SF/Yr at the entry level to $18 SF/Yr at the top of the market, averaging $18 SF/Yr. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. At $18 SF/Yr, the local average runs 42% below Massachusetts's state average of $30.83 SF/Yr.

Middleton accounts for 2% of the 165 retail properties & spaces currently available across Essex County, where nearby markets include Lynn and Lawrence.