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Highland, IL Retail Properties & Spaces for Lease

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Highland Retail/Office/Medical Spaces For Lease
$14 SF/Yr
1,775 SF

Highland Retail/Office/Medical Spaces For Lease

12603 State Rte 143, Highland, IL 62249

Office, retail, and medical spaces available for lease in Highland.

  • Located on IL‑143 with nearly 10,000 ADT.
  • Situated at a Lighted Intersection.
  • In front of R.P. Lumber.
  • Suite 8: 2,604 SF – Office/Medical space with Waiting Area, Reception Area, Private Therapy Room, 3 Treatment Bays, Open Therapy Area, Private Office, Storage Room and Restroom.
  • Suite 6: 1,775 SF – Retail/Office space with Open Work Area, Supply Room, Private Office, Showroom, Restroom.
Updated: Sep 22, 2025
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Highland Retail/Office Spaces Available
Contact for pricing
2,604 SF

Highland Retail/Office Spaces Available

12603 State Rte 143, Highland, IL 62249

Retail and office spaces for lease in Highland Shopping Center.

  • Located on IL‑143 with nearly 10,000 ADT (high traffic)
  • Situated at a Lighted Intersection in front of R.P. Lumber (high visibility)
  • Suite 8 (2,604 SF) ideal for Office/Medical use with existing layout including Waiting Area, Reception, and Therapy Rooms
  • Suite 6 (1,775 SF) suitable for Retail/Office with Open Work Area, Supply Room, Private Office, Showroom
  • Suite 5 (1,450 SF) – Former nail salon space
Updated: Feb 19, 2021
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Based on your search, we've compiled 17 Potential Opportunities for your consideration. Besides 2 Active listings in Highland, IL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 7 Properties for Sales.

Explore Retail properties & Spaces for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Retail Space in Troy Plaza
$13 SF/Yr
1,194 SF

Retail Space in Troy Plaza

Retail spaces available in well-located Troy Plaza Shopping Center.

525-547, Troy, IL
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Office/Retail Space on IL Route
Contact for pricing

Office/Retail Space on IL Route

Office and retail space with high visibility and access.

1 Executive Plaza Ct, Maryville, IL 62062
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Retail and Office Spaces Available
Contact for pricing
4,620 SF

Retail and Office Spaces Available

Retail and office spaces available for rent.

635 Edwardsville Rd, Troy, IL 62294
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Office/Retail Space Available
Contact for pricing
1,200 SF

Office/Retail Space Available

1,200 SF office/retail space with high visibility.

15 Executive Plaza Ct, Maryville, IL 62062
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Explore Similar Spaces for Sale in Highland, IL

Consider Similar Space for Sale. We found 7 Spaces matching your search parameters.

Prime Retail Building in Highland, IL
$275,000
3,080 SF

Prime Retail Building in Highland, IL

Well-located retail building with full basement and dedicated parking.

1018 Laurel Street, Highland, IL 62249
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Renovated Retail Space Near Square
$129,900
0.03 Acres

Renovated Retail Space Near Square

Updated retail space near Highland's vibrant square, great business opportunity.

1110 Washington Street, Highland, IL 62249
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Highland Commercial Building For Sale
$159,900
0.11 Acres

Highland Commercial Building For Sale

Vacant brick building in prime midtown location.

809 Main Street, Highland, IL 62249
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High Visibility Retail/Office Opportunity
$295,000

High Visibility Retail/Office Opportunity

Retail/office building with high traffic and dedicated parking.

12571 State Route 143, 2, Highland, IL 62249
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High Visibility Commercial Property
$295,000

High Visibility Commercial Property

Prime location with high traffic and recent upgrades.

12571 State Route 143 , 2, Highland, IL 62249
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Highland Commercial Site for Sale
$129,900
1,855 SF

Highland Commercial Site for Sale

Land available for build to suit near St. Joseph’s Hospital.

5 Apex & 20-25 Apex Dr, Highland, IL 62249
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Shovel Ready Commercial Sites
Contact for pricing
1,131,253 SF

Shovel Ready Commercial Sites

Commercial sites with utilities, roads, and water detention.

U.S. Hwy 40 & Commerce Lane, Highland, IL 62249
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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Retail Space in Orchard Town
Contact for pricing

Retail Space in Orchard Town

New retail development anchored by Meijer in Edwardsville, IL.

2319 Troy Rd, Edwardsville, IL 62025
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Development Lot For Lease/Sale
Contact for pricing

Development Lot For Lease/Sale

1 acre development lot available for lease or sale.

705 IL-157, Edwardsville, IL 62234
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Prime Commercial Lot For Lease
Contact for pricing

Prime Commercial Lot For Lease

3.64 AC lot in high-traffic area, ideal for retail.

O Fallon, IL 62269
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Regency Park Land For Rent
Contact for pricing

Regency Park Land For Rent

3.17 acres available in premier mixed-use development.

O Fallon, IL
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Highland, IL Retail properties & Spaces Leasing Opportunities Market Analysis

Explore Retail properties & Spaces leasing options in Highland, IL with 2 listings featured on our commercial real estate exchange. The current inventory includes 63,162,000 square feet of properties with an estimated lease value of $14 SF/Yr.

Estimated lease rates for Retail properties & Spaces in Highland, IL begin at $14 SF/Yr, with an average of $14 SF/Yr and extend to $14 SF/Yr.
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