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    Appleton, WI Office Units for Lease

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    Madison, WI Milwaukee, WI Brookfield, WI
    41 results
    Appleton Retail/Office Space Available
    $11 SF/Yr
    6,264 SF

    Appleton Retail/Office Space Available

    2021-2025 N Casaloma Dr, Appleton, WI

    Multi-tenant retail/office space in a high-traffic Appleton location.

    • High‑visibility location on N. Casaloma Drive, minutes from Interstate 41.
    • Located in Appleton's busiest retail corridor with many national and local retailers as neighbors.
    • Ample parking with 35 dedicated stalls.
    • Large monument and building signage available.
    • Neighbors include high‑traffic destinations such as Fox River Mall, Neuroscience Group Field/Timber Rattlers Stadium, and Fox Valley Technical Institute.
    Updated: Jun 18, 2025
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    Office Space with Highway Signage
    $15 SF/Yr
    1,250 SF

    Office Space with Highway Signage

    4000-4010 W Spencer St, Appleton, WI

    Office space with I-41 signage and abundant parking.

    • Signage adjacent to I‑41 with 100,000 visible vehicles per day.
    • Convenient access to major highways and public transportation.
    • Features four offices and a conference room.
    • Abundant parking.
    • Handicap accessible with an elevator.
    Updated: Oct 10, 2025
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    Historic Office Space on River
    $12 SF/Yr
    4,050 SF

    Historic Office Space on River

    Unique office space with river frontage near downtown Appleton.

    425 W Water St, Appleton, WI
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    Appleton Industrial Space For Lease
    $11 SF/Yr
    5,536 SF

    Appleton Industrial Space For Lease

    Office and warehouse space available in high-traffic Appleton location.

    2500 N Lynndale Dr, Appleton, WI
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    Office Space with High Visibility
    $8 SF/Yr
    1,660 SF

    Office Space with High Visibility

    Office suites available with excellent visibility and highway access.

    1011 N Lynndale Dr, Appleton, WI
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    Appleton Retail or Office Space
    $8 SF/Yr
    950 SF

    Appleton Retail or Office Space

    Retail or office space convenient to Highway 41.

    2400-2436 W Nordale Dr, Appleton, WI
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    Office Space on Fox River
    $20 SF/Yr
    2,200 SF

    Office Space on Fox River

    Multi-tenant retail/office center with ample parking and river views.

    161 S Riverheath Way, Appleton, WI
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    Corner Suite Retail/Office Space
    $14 SF/Yr
    1,703 SF

    Corner Suite Retail/Office Space

    Retail/office space with high traffic, signage, and parking.

    2107-2277 W Spencer St, Appleton, WI
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    Appleton Office Space For Rent
    Contact for pricing
    1,743 SF

    Appleton Office Space For Rent

    Well-maintained office building in professionally landscaped office park near College Avenue.

    446 N Westhill Blvd, Appleton, WI 54914
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    Downtown Commercial Space For Rent
    Contact for pricing
    1,910 SF

    Downtown Commercial Space For Rent

    Flexible commercial space in a prime downtown location.

    218 E College Ave, Appleton, WI 54911
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    Appleton Office Space Available
    $15 SF/Yr
    902 SF

    Appleton Office Space Available

    Well-maintained office building with generous parking and private entrances.

    35 Park Pl, Appleton, WI
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    Professional Office Space For Rent
    $16 SF/Yr
    375 SF

    Professional Office Space For Rent

    Professional office building on College Ave with ample parking.

    1033 W College Ave, Appleton, WI
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    Northland Avenue Office Space Available
    $12 SF/Yr
    1,675 SF

    Northland Avenue Office Space Available

    Office space for rent in high-traffic Appleton location.

    320 W Northland Ave, Appleton, WI
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    Downtown Second Floor Office Space
    $12 SF/Yr
    860 SF

    Downtown Second Floor Office Space

    Downtown office space with open workspaces, private offices, and amenities.

    338-344 W College Ave, Appleton, WI
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    Professional Office Space For Rent
    $26 SF/Yr

    Professional Office Space For Rent

    Multi-tenant office building on Appleton’s North side, near highways.

    3701 E Evergreen Dr, Appleton, WI
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    Appleton Office Space Available
    $16 SF/Yr
    5,240 SF

    Appleton Office Space Available

    5,240 square feet of office space for rent.

    2000 S Memorial Dr, Appleton, WI
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    Creative Office Space in Appleton
    $19 SF/Yr
    2,248 SF

    Creative Office Space in Appleton

    Creative office space for rent in downtown Appleton.

    513 W College Ave, Appleton, WI 54911
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    Multi-Tenant Office/Retail Space Available
    Contact for pricing

    Multi-Tenant Office/Retail Space Available

    Office/retail space with high visibility and ample parking.

    2021 N Casaloma Dr, Appleton, WI 54913
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    Office Space Near Retailers
    $24 SF/Yr

    Office Space Near Retailers

    Office space with easy access to amenities and transportation.

    54 Park Pl, Appleton, WI 54914
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    Appleton Office Space For Rent
    $3,540/Mo

    Appleton Office Space For Rent

    Flexible office spaces in Appleton with utilities included.

    626 E Longview Dr, Appleton, WI 54911
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    Retail/Office Space in Thriving Center
    Contact for pricing

    Retail/Office Space in Thriving Center

    Central suite ideal for retail or professional services.

    2197 W Spencer St, Appleton, WI 54914
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    Prime Location Office Space
    Contact for pricing

    Prime Location Office Space

    Office space near retailers and Interstate 41.

    17 Park Pl, Appleton, WI 54914
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    Office Space Near Retailers
    Contact for pricing

    Office Space Near Retailers

    Office space with easy access and close to national retailers.

    47 Park Pl, Appleton, WI 54914
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    Appleton Office Space For Rent
    $16 SF/Yr
    3,000 SF

    Appleton Office Space For Rent

    Multi-tenant office building near Fox River Mall with ample parking.

    5600 W Grande Market Dr, Appleton, WI
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    Appleton, WI Office Units Leasing Opportunities Market Analysis

    Explore Office Units leasing options in Appleton, WI with 41 listings featured on our commercial real estate exchange. The current inventory includes 1,758,865,680 square feet of properties with an estimated lease value of $114 SF/Yr.

    Estimated lease rates for Office Units in Appleton, WI begin at $11 SF/Yr, with an average of $14 SF/Yr and extend to $20 SF/Yr.
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    Most Searched ZIP Codes in Appleton, WI

    • 54914
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    • 54913
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