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    Poughkeepsie, NY Office Units for Lease

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    Highland, NY Milton, NY Hyde Park, NY
    56 listings
    Open-Concept Storefront with Loft Finish
    $2,000/Mo
    817 SF
    Open-Concept Storefront with Loft Finish

    204 Main Street, Poughkeepsie, NY 12601

    Ground-floor retail space with street-facing floor-to-ceiling windows, updated private bathroom, and C-2 zoning for flexible uses.
    • Ground‑floor commercial unit at 204 Main Street with approximately 817 SF and an open‑concept layout
    • Storefront with large floor‑to‑ceiling windows for natural light and street‑facing presence on Main Street
    • Original exposed brick, hardwood flooring, and high ceilings create a loft‑style interior
    • Includes an updated private bathroom plus a kitchenette/utility area for staff use
    • Zoning supports a variety of permitted uses, including boutique retail, professional offices, creative studios/small galleries, and personal service businesses
    Updated: Feb 21
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    Historic Trolley Barn Storefront
    $4,000/Mo
    Historic Trolley Barn Storefront

    489 Main Street, Poughkeepsie, NY 12601

    Renovated event, art gallery, and storefront space with skylights, high ceilings, and flexible MU-5 zoning for multiple uses.
    • Historic trolley barn converted into a 3,400 SF event space/art gallery/storefront
    • Second floor mezzanine plus an 8,000 SF rear loft area with 35 ft ceilings and skylights
    • Facade restoration completed in 2018, with utilities and structural upgrades
    • Flexible zoning allows retail, food, arts, office, medical, and hospitality uses
    • Construction includes block and brick; flooring is concrete; heated with natural gas and cooled with central air
    Updated: Jun 18
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    Downtown Poughkeepsie Office Space
    $2,600/Mo
    1,100 SF
    Downtown Poughkeepsie Office Space

    Professional office suite in downtown Poughkeepsie with utilities included.

    55 Market, Poughkeepsie, NY 12601

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    Renovated Office Space in Poughkeepsie
    $1,900/Mo
    700 SF
    Renovated Office Space in Poughkeepsie

    Newly renovated office space in downtown Poughkeepsie for lease.

    55 Market, Poughkeepsie, NY 12601

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    Poughkeepsie First-Floor Office Space
    $1,150/Mo
    368 SF
    Poughkeepsie First-Floor Office Space

    Versatile 368 SF office space in prime Poughkeepsie location.

    53 Market Street, Poughkeepsie, NY 12601

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    Poughkeepsie First-Floor Office Space
    $1,150/Mo
    372 SF
    Poughkeepsie First-Floor Office Space

    Versatile 372 SF office space in prime Poughkeepsie location.

    53 Market Street, Poughkeepsie, NY 12601

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    Freestanding Retail and Office Building
    $22 SF/Yr
    9,500 SF
    Freestanding Retail and Office Building

    Freestanding building with ground-level retail space plus a small second-floor office component and strong corridor visibility.

    611 Dutchess Turnpike, Arlington, NY 12603

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    Renovated Medical Office Suite
    $3,100/Mo
    1,300 SF
    Renovated Medical Office Suite

    Updated office suite with private exam rooms, reception, and on-site parking near Metro-North access.

    56 Main Street #1, Poughkeepsie, NY 12601

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    Turn-Key Medical Office Suite
    $2,900/Mo
    1,300 SF
    Turn-Key Medical Office Suite

    Renovated second-floor medical office with multiple exam rooms, conference space, and dedicated on-site parking options.

    56 Main Street #2, Poughkeepsie, NY 12601

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    Professional Office Suite For Lease
    $2,750/Mo
    1,100 SF
    Professional Office Suite For Lease

    Adaptable 1,100 SF office suite in Poughkeepsie, NY.

    51 Springside Ave 3, Poughkeepsie, NY 12603

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    Two-Story Office Building with Road Frontage
    $18 SF/Yr
    4,556 SF
    Two-Story Office Building with Road Frontage

    Two-story office building with direct road frontage along U.S. Route 44 and NYS Route 55 in Poughkeepsie.

    303 Mill Street, Poughkeepsie, NY 12601

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    Poughkeepsie First-Floor Office Space
    $1,150/Mo
    372 SF
    Poughkeepsie First-Floor Office Space

    Versatile 372 SF office space in prime Poughkeepsie location.

    53 Market St 3A, Poughkeepsie, NY 12601

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    Ground-Floor Office/Retail Space Available
    $1,500/Mo
    1,257 SF
    Ground-Floor Office/Retail Space Available

    Open floorplan office/retail space with private entrance and restroom.

    63 Cannon St, Poughkeepsie, NY 12601

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    Office Suite with Private Entry
    $1,100/Mo
    Office Suite with Private Entry

    Corner office suite with private, handicap-accessible entrance, multiple interior offices, and an in-suite bathroom.

    2038 New Hackensack Rd 3, Poughkeepsie, NY 12603

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    Downtown Professional Office Suite
    $2,600/Mo
    1,100 SF
    Downtown Professional Office Suite

    Second-floor suite with four private rooms, a large conference room, and skylight natural light for professional services.

    3b-55 Market St, Poughkeepsie, NY 12601

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    Adaptable Commercial Space in Poughkeepsie
    $11,492/Mo
    4,925 SF
    Adaptable Commercial Space in Poughkeepsie

    Flexible 4,925 SF suite suitable for diverse commercial uses.

    25 Van Wagner Road #1A, Poughkeepsie, NY 12603

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    Poughkeepsie Professional Office Space
    $5,500/Mo
    Poughkeepsie Professional Office Space

    Standalone office space in Arlington District, ideal for professionals.

    97 Fulton Ave, Poughkeepsie, NY 12603

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    Poughkeepsie Commercial Space Available
    $2,400/Mo
    Poughkeepsie Commercial Space Available

    Commercial space for rent in a centrally located Poughkeepsie area.

    348 Main St, Poughkeepsie, NY 12601

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    Professional Office Suite For Lease
    $2,750/Mo
    1,100 SF
    Professional Office Suite For Lease

    Refined 1,100 sq ft office suite in Poughkeepsie.

    51 Springside Avenue #3, Poughkeepsie, NY 12603

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    Versatile Office Space in Poughkeepsie
    $18 SF/Yr
    5,100 SF
    Versatile Office Space in Poughkeepsie

    Office and gallery space near transportation and parking.

    100 Cannon St, Poughkeepsie, NY

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    Poughkeepsie First-Floor Office Space
    $1,150/Mo
    368 SF
    Poughkeepsie First-Floor Office Space

    Versatile 368 SF office space in central Poughkeepsie.

    53 Market Street #5A, Poughkeepsie, NY 12601

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    Small Office Space Available
    $250 SF/Yr
    Small Office Space Available

    Second-floor office unit for lease with parking and signage.

    383-385 Hooker Avenue #4, Poughkeepsie, NY 12603

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    Poughkeepsie First-Floor Versatile Office Space
    $1,150/Mo
    372 SF
    Poughkeepsie First-Floor Versatile Office Space

    First-floor office space in Poughkeepsie, suitable for various businesses.

    53 Market Street #3A, Poughkeepsie, NY 12601

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    Poughkeepsie Commercial Space For Rent
    $1,850/Mo
    Poughkeepsie Commercial Space For Rent

    Versatile commercial space in Poughkeepsie's Arlington District.

    826 Main Street #824, Poughkeepsie, NY 12603

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    Poughkeepsie, NY Office Units Market Trends and Statistics

    Explore Office Units leasing options in Poughkeepsie, NY with 56 listings featured on our commercial real estate exchange. The current inventory includes 62,069 square feet of properties with an estimated lease value of $501,175.

    Estimated lease rates for Office Units in Poughkeepsie, NY begin at $14 SF/Yr, with an average of $13,921 /Mo and extend to $500,000.
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