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    Yankton, SD Office Spaces for Sale

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    Saint Helena, NE Crofton, NE Mission Hill, SD Gayville, SD Volin, SD Vermillion, SD Tabor, SD Hartington, NE
    Turnkey Veterinary Facility
    Updated: Oct 14, 2025
    Turnkey Veterinary Facility

    1603 Broadway Ave, Yankton, SD 57078

    $999,900
    3,480 sqft
    Turnkey veterinary operation with grooming and boarding setup
    Established business on Yankton’s Broadway Avenue since 1989
    Fully equipped for a pet grooming and boarding division
    Up to 13 off‑street parking spaces for customers
    6+ on‑street (employee) parking spaces
    View details
    Downtown Yankton Mixed-Use Opportunity
    Updated: Mar 12
    Downtown Yankton Mixed-Use Opportunity

    321 Douglas Ave, Yankton, SD 57078

    $295,000
    5,336 sqft
    Prime downtown Yankton location with high visibility and walkable access to the commercial core.
    Over 5,300 sq ft of flexible space suitable for retail, office, studio, or residential use.
    Mixed‑use opportunity for investors or owner‑operators with income potential from upper level.
    Adaptable 3,800+ sq ft main floor previously used as a dance studio, ready for customization.
    Value‑add potential for redevelopment or continued studio‑style use.
    View details
    Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center
    Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 2 Active listings in Yankton, SD, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 70 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Standalone Corner Office Building
    Standalone Corner Office Building

    102 N Broadway Ave, Hartington, NE 68739

    $297,900
    0.12 AC lot

    Standalone office building with five offices and corner visibility, suited for professional service tenants in downtown Hartington.

    View details
    Standalone Corner Office Building
    Standalone Corner Office Building

    102 W Main St, Hartington, NE 68739

    $152,000
    0.09 AC lot

    Solid brick office building with a full basement and multiple private offices plus lobby and conference room.

    View details
    Downtown Office Building Opportunity
    Downtown Office Building Opportunity

    11 E Main St, Vermillion, SD 57069

    $250,000

    Vacant office building with seven main-floor offices and additional basement space with two separate entrances.

    View details
    Versatile Commercial Property For Sale
    Versatile Commercial Property For Sale

    1325 E Cherry Street, Vermillion, SD 57069

    $298,000
    1,800 sqft 0.36 AC lot

    Mixed-use commercial property suitable for retail, office, or industrial use.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    General Business Lot with Visibility
    General Business Lot with Visibility

    2001 Jack Nicklaus Dr., Elk Point, SD 57025

    $87,352
    0.51 AC lot

    Zoned GB, this roughly half-acre commercial lot offers visibility from Main Street for a variety of business uses.

    View details
    General Commercial Lot at Intersection
    General Commercial Lot at Intersection

    500 N Heritage Pkwy, Tea, SD 57064

    $220,000
    0.68 AC lot

    General commercial lot at the intersection of Heritage Parkway and Kevin Drive in Tea, SD, across from multiple retail and service uses.

    View details
    Undeveloped Corner Land Parcel
    Undeveloped Corner Land Parcel

    27002 S Louise Ave, Sioux Falls, SD 57108

    $7,960,000
    45.53 AC lot

    Large undeveloped corner parcel with significant frontage on S Louise Ave, W 85th St, and Meredith Ave.

    View details
    Commercial Land For Sale
    Commercial Land For Sale

    5021 South Rateliff Avenue, Sioux Falls, SD 57108

    Contact for pricing

    Commercial land available for sale.

    View details

    Off-Market Properties in Yankton, SD

    Consider similar Off-Market properties in Yankton, SD. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    420 Broadway Ave
    OFFICE BUILDING

    420 Broadway Ave, Yankton, SD 57078-4305

    Value Estimation by Request
    2,640 sqft 0.15 AC lot
    View details
    918 Hwy 50
    OFFICE BUILDING

    918 Hwy 50, Yankton, SD 57078

    Value Estimation by Request
    1,050 sqft 0.89 AC lot
    View details
    101 2nd St
    OFFICE BUILDING

    101 2nd St, Yankton, SD 57078-4314

    Value Estimation by Request
    11,400 sqft 0.48 AC lot
    View details
    319 Walnut St
    OFFICE BUILDING

    319 Walnut St, Yankton, SD 57078-4344

    Value Estimation by Request
    14,614 sqft 0.20 AC lot
    View details
    31105 436th Ave
    PROFESSIONAL BUILDING

    31105 436th Ave, Yankton, SD 57078-5960

    Value Estimation by Request
    864 sqft 1.64 AC lot
    View details
    603 21st St
    OFFICE BUILDING

    603 21st St, Yankton, SD 57078-2086

    Value Estimation by Request
    1,584 sqft 0.22 AC lot
    View details
    201 Broadway Ave
    OFFICE BUILDING

    201 Broadway Ave, Yankton, SD 57078-4211

    Value Estimation by Request
    1,700 sqft 0.15 AC lot
    View details
    610 23rd St
    OFFICE BUILDING

    610 23rd St, Yankton, SD 57078-1218

    $1,405,000
    Estimated value
    15,084 sqft 3.29 AC lot
    View details
    2006 Locust St
    OFFICE BUILDING

    2006 Locust St, Yankton, SD 57078-2031

    Value Estimation by Request
    936 sqft 0.20 AC lot
    View details
    402 3rd St
    OFFICE BUILDING

    402 3rd St, Yankton, SD 57078-4513

    Value Estimation by Request
    2,640 sqft 0.13 AC lot
    View details
    1603 Locust St
    OFFICE BUILDING

    1603 Locust St, Yankton, SD 57078-2017

    Value Estimation by Request
    5,100 sqft 0.60 AC lot
    View details
    606 Goeden Dr
    OFFICE BUILDING

    606 Goeden Dr, Yankton, SD 57078-2083

    Value Estimation by Request
    3,584 sqft 0.33 AC lot
    View details
    800 Burleigh St
    OFFICE BUILDING

    800 Burleigh St, Yankton, SD 57078-3197

    Value Estimation by Request
    982 sqft 0.52 AC lot
    View details
    904 23rd St
    OFFICE BUILDING

    904 23rd St, Yankton, SD 57078-1216

    Value Estimation by Request
    20,388 sqft 1.67 AC lot
    View details
    2300 15th St
    OFFICE BUILDING

    2300 15th St, Yankton, SD 57078-6543

    Value Estimation by Request
    1,344 sqft 2.71 AC lot
    View details
    614 Broadway Ave
    OFFICE BUILDING

    614 Broadway Ave, Yankton, SD 57078-3516

    Value Estimation by Request
    5,772 sqft 0.45 AC lot
    View details
    216 3rd St
    OFFICE BUILDING

    216 3rd St, Yankton, SD 57078-4323

    Value Estimation by Request
    2,256 sqft 0.06 AC lot
    View details
    3608 Hwy 50
    OFFICE BUILDING

    3608 Hwy 50, Yankton, SD 57078-6526

    $795,000
    Estimated value
    7,000 sqft 1.91 AC lot
    View details
    809 Belfast St
    MEDICAL BUILDING

    809 Belfast St, Yankton, SD 57078-3324

    Value Estimation by Request
    2,482 sqft 0.30 AC lot
    View details
    207 Douglas Ave
    OFFICE BUILDING

    207 Douglas Ave, Yankton, SD 57078-4338

    Value Estimation by Request
    7,560 sqft 0.45 AC lot
    View details
    202 2nd St
    OFFICE BUILDING

    202 2nd St, Yankton, SD 57078-4317

    Value Estimation by Request
    2,821 sqft 0.15 AC lot
    View details
    2001 Broadway Ave
    MEDICAL BUILDING

    2001 Broadway Ave, Yankton, SD 57078-2032

    Value Estimation by Request
    2,000 sqft 0.23 AC lot
    View details

    Yankton, SD Office Spaces Market Trends and Statistics

    Explore 72 office spaces for sale in Yankton, SD on our real estate platform. These investment opportunities span a total of 8,816 square feet of properties for sale, with an estimated market value of $1,294,900.

    Sale prices for office spaces in Yankton, SD start at $295,000, averaging $647,450, and reaching up to $999,900 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Office Units 5
    Medical Office Space 1

    Demographics Overview

    Population 21K
    Population Growth (5Y) +7.5%
    Median Household Income $72,395
    College Educated 19.8%

    High-Yield Neighborhoods for Investment

    Identify Yankton submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    57078 $745K

    Taxes & Financing

    Tax Rate (average for all types) 1.54%
    Property Tax per SF $26.14 per SF
    Tax Rate vs County Average 0.01 pp above county avg
    Average Loan-to-Value 65.0%

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