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    Greenwood, SC Office Properties & Spaces for Sale

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    Versatile Commercial Building, Greenwood SC
    $159,000
    1,722 SF

    Versatile Commercial Building, Greenwood SC

    1601 E Cambridge Ave, Greenwood, SC 29646

    Adaptable commercial building with high visibility and flexible build-out options.

    • High‑visibility corner location with strong road presence
    • Large, open interior with high ceilings and exposed framing, ideal for customization
    • Flexible build‑out options suitable for retail, light industrial, workshop, studio, storage, or office conversion
    • Generous lot space for parking, storage, or expansion
    • Durable block construction
    Updated: Feb 3
    View details
    Historic Uptown Greenwood Commercial Property
    $749,000
    4,684 SF

    Historic Uptown Greenwood Commercial Property

    206 Main St, Greenwood, SC 29649

    Versatile commercial space in a vibrant historic district with unique features.

    • Prime Location: Situated in the heart of Uptown Greenwood with high visibility and foot traffic.
    • Versatile Space: Just under 5,000 sqft with a flexible layout suitable for retail, office, or mixed‑use purposes. Includes seven private office suites, a shared kitchenette, and a large basement.
    • Historic Charm: Features original hardwood floors, ghost murals (including a vintage Coca‑Cola mural), and architectural details reflecting its 1917 origins.
    • Ample Parking: Benefits from an expansive city‑owned front lot providing abundant parking.
    • Turnkey Opportunity: Includes all remaining furnishings upstairs, making it ready for a new business/owner.
    Updated: Sep 9, 2025
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    Greenwood Commercial Building with Warehouse
    $395,000
    10,000 SF

    Greenwood Commercial Building with Warehouse

    Office, showroom, and warehouse on a large corner lot.

    1201 Cambridge Ave, Greenwood, SC 29649
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    Uptown Greenwood Multi-Use Corner Building
    $750,000
    5,308 SF

    Uptown Greenwood Multi-Use Corner Building

    Three-level commercial building with retail, office, and storage space.

    202 Main St, Greenwood, SC 29646
    View details
    Based on your search, we've compiled 232 Potential Opportunities for your consideration. Besides 4 Active listings in Greenwood, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 220 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Historic Abbeville Property on Main
    $299,900
    0.21 Acres

    Historic Abbeville Property on Main

    Remarkable 1820 property, ideal for office or retail.

    204 S Main St, Abbeville, SC 29620
    View details
    Historic Property with Endless Possibilities
    $650,000
    6,057 SF

    Historic Property with Endless Possibilities

    Unique turn-of-the-century property near downtown square, ideal for redevelopment.

    208 S Main St, Abbeville, SC 29620
    View details
    High-Visibility Commercial Property in Calhoun Falls
    $389,999
    5,000 SF

    High-Visibility Commercial Property in Calhoun Falls

    Commercial property in Calhoun Falls, SC, ideal for retail or office.

    546 East Savannah Street Ext, Calhoun Falls, SC 29628
    View details
    Calhoun Falls Commercial Building For Sale
    $410,000
    2,740 SF

    Calhoun Falls Commercial Building For Sale

    Freestanding commercial building in Calhoun Falls, SC, ideal for various uses.

    253 E Savannah St, Calhoun Falls, SC 29628
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Greenwood Commercial Corner Lot Opportunity
    $174,000
    0.54 Acres

    Greenwood Commercial Corner Lot Opportunity

    Prime commercial lot in Greenwood's active corridor, ideal for development.

    441/443 Calhoun Ave, Greenwood, SC 29649
    View details
    Greenwood Commercial Acreage Opportunity
    $4,300,000
    11.46 Acres

    Greenwood Commercial Acreage Opportunity

    11.46 acres zoned C2 in prime Greenwood location.

    508 Old Abbeville Hwy, Greenwood, SC 29646
    View details
    Commercial Land on Montague Ave
    $135,000
    0.49 Acres

    Commercial Land on Montague Ave

    Half-acre commercial tract in high-traffic location, ready for business.

    1438 Montague Avenue Ext, Greenwood, SC 29649
    View details
    Commercial Lots on High-Traffic Highway
    $149,000
    1.73 Acres

    Commercial Lots on High-Traffic Highway

    Prime commercial land with high visibility and growth potential.

    2611 Hwy 25S, Greenwood, SC 29646
    View details

    Explore Off-Market Properties in Greenwood, SC

    Consider similar Off-Market properties in Greenwood, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    1202 Hwy 72nd W

    1202 Hwy 72nd W

    MEDICAL BUILDING • 4,590 SF
    Value Estimation by Request
    1202 Hwy 72nd W, Greenwood, SC 29649-1816
    View details
    102 Katie Ct

    102 Katie Ct

    MEDICAL BUILDING • 6,521 SF
    Value Estimation by Request
    102 Katie Ct, Greenwood, SC 29646-4068
    View details
    123 High St

    123 High St

    OFFICE BUILDING • 1,862 SF
    Value Estimation by Request
    123 High St, Greenwood, SC 29649-1925
    View details
    1013 Spg St

    1013 Spg St

    MEDICAL BUILDING • 12,541 SF
    Value Estimation by Request
    1013 Spg St, Greenwood, SC 29646
    View details
    212 Oak Ave

    212 Oak Ave

    OFFICE BUILDING • 4,124 SF
    Value Estimation by Request
    212 Oak Ave, Greenwood, SC 29646-2625
    View details
    231 Hampton Ave Ste F

    231 Hampton Ave Ste F

    OFFICE BUILDING • 750 SF
    Value Estimation by Request
    231 Hampton Ave Ste F, Greenwood, SC 29646-2299
    View details
    200 Main N St

    200 Main N St

    OFFICE BUILDING • 2,000 SF
    Value Estimation by Request
    200 Main N St, Greenwood, SC 29646-2242
    View details
    1226 Spg St

    1226 Spg St

    MEDICAL BUILDING • 3,135 SF
    Value Estimation by Request
    1226 Spg St, Greenwood, SC 29646-3835
    View details
    327 Main St, Unit 6

    327 Main St, Unit 6

    OFFICE BUILDING • 1,817 SF
    Value Estimation by Request
    327 Main St, Greenwood, SC 29646-1601
    View details
    327 Main St, Unit 3

    327 Main St, Unit 3

    OFFICE BUILDING • 1,817 SF
    Value Estimation by Request
    327 Main St, Greenwood, SC 29646-1601
    View details
    1402 Hwy 72nd W

    1402 Hwy 72nd W

    OFFICE BUILDING • 6,388 SF
    Value Estimation by Request
    1402 Hwy 72nd W, Greenwood, SC 29649-1822
    View details
    1201 Cambridge E Ave

    1201 Cambridge E Ave

    OFFICE BUILDING • 10,207 SF
    Value Estimation
    $565,000
    1201 Cambridge E Ave, Greenwood, SC 29646-3071
    View details
    339 Grace St

    339 Grace St

    OFFICE BUILDING • 864 SF
    Value Estimation by Request
    339 Grace St, Greenwood, SC 29649-2417
    View details
    1404 Edgefield St

    1404 Edgefield St

    MEDICAL BUILDING • 3,600 SF
    Value Estimation by Request
    1404 Edgefield St, Greenwood, SC 29646-4014
    View details
    219 Waller Ave

    219 Waller Ave

    OFFICE BUILDING • 9,420 SF
    Value Estimation
    $520,000
    219 Waller Ave, Greenwood, SC 29646
    View details
    128 Maxwell Ave

    128 Maxwell Ave

    OFFICE BUILDING • 2,628 SF
    Value Estimation by Request
    128 Maxwell Ave, Greenwood, SC 29646-2641
    View details
    201 Hampton Ave Ste C

    201 Hampton Ave Ste C

    OFFICE BUILDING • 1,050 SF
    Value Estimation by Request
    201 Hampton Ave Ste C, Greenwood, SC 29646-2271
    View details
    711 Montague Ave

    711 Montague Ave

    MEDICAL BUILDING • 2,410 SF
    Value Estimation by Request
    711 Montague Ave, Greenwood, SC 29649-1440
    View details
    314 Cambridge W Ave

    314 Cambridge W Ave

    OFFICE BUILDING • 2,240 SF
    Value Estimation by Request
    314 Cambridge W Ave, Greenwood, SC 29646-2190
    View details
    207 Montague Ave

    207 Montague Ave

    OFFICE BUILDING • 3,455 SF
    Value Estimation by Request
    207 Montague Ave, Greenwood, SC 29649-1936
    View details

    Greenwood, SC Office Properties & Spaces Investment Opportunities Market Analysis

    Explore 224 office properties & spaces for sale in Greenwood, SC, showcased through 4 active listings on our real estate platform. These investment opportunities span a total of 4,810,679 square feet of properties for sale, with an estimated market value of $43,179,000.

    Sale prices for office spaces in Greenwood, SC start at $80,000, averaging $981,340, and reaching up to $12,245,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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