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    Greenwood, SC Office Properties & Spaces for Sale

    10 results
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    Versatile Commercial Flex Property
    $799,900
    6,000 SF

    Versatile Commercial Flex Property

    463 Calhoun, Greenwood, SC 29646

    6,000 sq ft commercial flex property in Greenwood, SC.

    • 6,000 sq ft commercial flex property in a thriving commercial district.
    • Potential to reconfigure into 4 units for increased rental income.
    • Currently divided into 3 units (3,000 sq ft, two 1,500 sq ft units) offering immediate income potential.
    • Recently resurfaced parking lot providing ample parking.
    • Ideal for a mix of office, retail, or light industrial use.
    Updated: Mar 17
    View details
    Greenwood Commercial Building with Warehouse
    $395,000
    10,000 SF

    Greenwood Commercial Building with Warehouse

    1201 Cambridge Av, Greenwood, SC 29649

    Office, showroom, and warehouse on a large corner lot.

    • Prime location in Greenwood's busiest corridor with excellent visibility and high traffic count.
    • Combination office, showroom, and warehouse space totaling over 10,200 sq ft (4,000+ sq ft finished office/showroom, 6,200+ sq ft warehouse).
    • Five roll‑up bay doors provide easy warehouse access within a fenced area.
    • Durable concrete frame, stucco, and metal construction.
    • Priced at $395,000, offering a rare opportunity for owner‑users or investors.
    Updated: Sep 17, 2025
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    Versatile Commercial Building, Greenwood SC
    $159,000
    1,722 SF

    Versatile Commercial Building, Greenwood SC

    Adaptable commercial building with high visibility and flexible build-out options.

    1601 E Cambridge Ave, Greenwood, SC 29646
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    Historic Uptown Greenwood Commercial Property
    $749,000
    4,684 SF

    Historic Uptown Greenwood Commercial Property

    Versatile commercial space in a vibrant historic district with unique features.

    206 Main St, Greenwood, SC 29649
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    Greenwood Commercial Acreage For Sale
    $350,000
    1.80 Acres

    Greenwood Commercial Acreage For Sale

    1.8 acre commercial lot with high visibility and traffic.

    1421 Cambridge Avenue, Greenwood, SC 29646
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    Iconic Mixed-Use Property, Greenwood SC
    $479,000
    4,753 SF

    Iconic Mixed-Use Property, Greenwood SC

    Mixed-use property in vibrant Uptown Greenwood, ideal for live/work.

    204 Main Street, Greenwood, SC 29649
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    Greenwood Historic Building Fifth Floor
    $50,000
    1,817 SF

    Greenwood Historic Building Fifth Floor

    Fifth floor of historic building suitable for commercial or residential.

    327 Main St, Greenwood, SC 29646
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    Uptown Greenwood Multi-Use Corner Building
    $750,000
    5,308 SF

    Uptown Greenwood Multi-Use Corner Building

    Three-level commercial building with retail, office, and storage space.

    202 Main St., Greenwood, SC 29646
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    Versatile Commercial Property in Greenwood
    $369,000
    8,272 SF

    Versatile Commercial Property in Greenwood

    High-visibility commercial property with multiple buildings and flexible spaces.

    1107 Reynolds Ave, Greenwood, SC 29649
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    Retail Building on Crosscreek Connector
    $525,000
    4,320 SF

    Retail Building on Crosscreek Connector

    Retail building on one acre with expansion potential.

    167 Crosscreek Connector, Greenwood, SC 29649
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    Based on your search, we've compiled 238 Potential Opportunities for your consideration. Besides 10 Active listings in Greenwood, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 220 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Historic Property with Endless Possibilities
    $650,000
    6,057 SF

    Historic Property with Endless Possibilities

    Unique turn-of-the-century property near downtown square, ideal for redevelopment.

    208 S Main St, Abbeville, SC 29620
    View details
    Commercial Shop Space For Sale
    $200,000
    0.33 Acres

    Commercial Shop Space For Sale

    Well-maintained commercial shop space ideal for various business operations.

    510 Anderson Drive, Laurens, SC 29360
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    Historic Abbeville Property on Main
    $299,900
    0.21 Acres

    Historic Abbeville Property on Main

    Remarkable 1820 property, ideal for office or retail.

    204 S Main Street, Abbeville, SC 29620
    View details
    Laurens Commercial Building For Sale
    $379,000
    2,790 SF

    Laurens Commercial Building For Sale

    Commercial building with two business suites, suitable for various uses.

    328 Hillcrest Dr, Laurens, SC 29360
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Greenwood Commercial Acreage For Sale
    $695,000
    5.89 Acres

    Greenwood Commercial Acreage For Sale

    5.89 acres of commercial land with high exposure.

    5.89 ac Montague Ave Ext, Greenwood, SC 29649
    View details
    Commercial Land on Highway 72
    $69,000
    0.37 Acres

    Commercial Land on Highway 72

    High-visibility commercial land with office building and highway frontage.

    0 0 Hwy 72 W, Abbeville, SC 29620
    View details
    Prime Commercial Lot in Laurens
    $295,000
    2.88 Acres

    Prime Commercial Lot in Laurens

    2.88-acre commercial lot with high visibility and easy access.

    571 Highway 221, Laurens, SC 29360
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    Prime Commercial Lot in Laurens
    $295,000
    2.88 Acres

    Prime Commercial Lot in Laurens

    2.88-acre commercial lot with high visibility and easy access.

    571 Highway 221, Laurens, SC 29360
    View details

    Explore Off-Market Properties in Greenwood, SC

    Consider similar Off-Market properties in Greenwood, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    101 Gregor Mendel Cir

    101 Gregor Mendel Cir

    MEDICAL BUILDING • 29.81 Acres
    Value Estimation by Request
    101 Gregor Mendel Cir, Greenwood, SC 29646-2316
    View details
    109 Bailey St

    109 Bailey St

    OFFICE BUILDING • 1,966 SF
    Value Estimation by Request
    109 Bailey St, Greenwood, SC 29649
    View details
    210 Montague Ave

    210 Montague Ave

    OFFICE BUILDING • 3,083 SF
    Value Estimation by Request
    210 Montague Ave, Greenwood, SC 29649-1935
    View details
    212 Grace St

    212 Grace St

    OFFICE BUILDING • 2,793 SF
    Value Estimation by Request
    212 Grace St, Greenwood, SC 29649-2412
    View details
    425 Emerald N Rd

    425 Emerald N Rd

    OFFICE BUILDING • 5,750 SF
    Value Estimation by Request
    425 Emerald N Rd, Greenwood, SC 29646-3062
    View details
    514 Laurel E Ave

    514 Laurel E Ave

    OFFICE BUILDING • 1,500 SF
    Value Estimation by Request
    514 Laurel E Ave, Greenwood, SC 29649-1647
    View details
    605 Calhoun Ave

    605 Calhoun Ave

    OFFICE BUILDING • 1,981 SF
    Value Estimation by Request
    605 Calhoun Ave, Greenwood, SC 29649-1903
    View details
    1128 Main S St

    1128 Main S St

    OFFICE BUILDING • 1,500 SF
    Value Estimation by Request
    1128 Main S St, Greenwood, SC 29646-3842
    View details
    317 Emerald N Rd

    317 Emerald N Rd

    MEDICAL BUILDING • 3,000 SF
    Value Estimation by Request
    317 Emerald N Rd, Greenwood, SC 29646-3050
    View details
    516 Montague Ave

    516 Montague Ave

    MEDICAL BUILDING • 6,139 SF
    Value Estimation by Request
    516 Montague Ave, Greenwood, SC 29649-1942
    View details
    201 Hampton Ave Ste F

    201 Hampton Ave Ste F

    MEDICAL BUILDING • 1,344 SF
    Value Estimation by Request
    201 Hampton Ave Ste F, Greenwood, SC 29646-2271
    View details
    110 Riley Ave

    110 Riley Ave

    OFFICE BUILDING • 1,178 SF
    Value Estimation by Request
    110 Riley Ave, Greenwood, SC 29646-2739
    View details
    107 Venture Ct

    107 Venture Ct

    OFFICE BUILDING • 2,218 SF
    Value Estimation by Request
    107 Venture Ct, Greenwood, SC 29649-8558
    View details
    1111 Edgefield St

    1111 Edgefield St

    MEDICAL BUILDING • 1,424 SF
    Value Estimation by Request
    1111 Edgefield St, Greenwood, SC 29646-3849
    View details

    Greenwood, SC Office Properties & Spaces Investment Opportunities Market Analysis

    Explore 230 office properties & spaces for sale in Greenwood, SC, showcased through 10 active listings on our real estate platform. These investment opportunities span a total of 4,833,766 square feet of properties for sale, with an estimated market value of $44,457,900.

    Sale prices for office spaces in Greenwood, SC start at $80,000, averaging $966,476, and reaching up to $12,245,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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