Lancaster, OH Office Properties & Spaces for Rent & Lease

Downtown Lancaster Second-Floor Office Space

$8 SF/Yr

34,896 SF

Downtown Lancaster Second-Floor Office Space

230 N Columbus St, Lancaster, OH 43130

Second-floor office space for lease in downtown Lancaster, Ohio.

Prime downtown Lancaster location
Flexible office space with various sized offices, conference rooms, and activity rooms
Affordable rent at $8.00/SF on a Gross Lease
Elevator access to the second floor
Parking available in a neighboring lot

Updated: Nov 9, 2025

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Downtown Lancaster Office Suite For Rent

$3,683 / Mo

9,300 SF

Downtown Lancaster Office Suite For Rent

113 W Wheeling St, Lancaster, OH 43130

Prime office suite in downtown Lancaster, available March 1, 2026.

Prime 3,400 sq ft first‑floor office suite in downtown Lancaster.
Steps from businesses, banks, restaurants, City Hall, and courthouses.
Seven private offices plus two spacious conference/training rooms.
Off‑street parking provides excellent accessibility and visibility.
Move‑in ready condition.

Updated: Jan 25

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$16 SF/Yr

15,948 SF

New Lancaster Office Space Available

New office buildings with build-to-suit options in Lancaster, OH.

2656 N Columbus St, Lancaster, OH 43130

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$132 SF/Yr

51,000 SF

East Main Street Office Space

Lancaster, OH Office Building - High Visibility

1145 Main St, Lancaster, OH 43130

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$168 SF/Yr

4,100 SF

Lancaster Medical Office Building

Modern Medical Office Space Available

2656 Columbus St, Lancaster, OH 43130

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$14 SF/Yr

23,159 SF

Lancaster Medical Office Building

Prime Lancaster medical space available.

2405 Columbus St, Lancaster, OH 43130

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$14 SF/Yr

12,584 SF

Medical Office Building For Lease

Multi-tenant medical office building with surgical center and renovated common areas.

2405 North Columbus St, Lancaster, OH 43130

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Contact for pricing

30,000 SF

Lancaster Office Space Available

30,000 square feet of office space for rent.

1432 NW Collins Rd, Lancaster, OH 43130

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Based on your search, we've compiled 17 Potential Opportunities for your consideration. Besides 8 Active listings in Lancaster, OH, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 5 Properties for Sales.

Explore Office Properties & Spaces for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Pickerington Office/Medical Building For Lease

$4,500 / Mo

3,510 SF

Pickerington Office/Medical Building For Lease

Two-story building for lease in a busy, developing area.

9 Hill Rd N, Pickerington, OH 43147

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Contact for pricing

Prime Location Near OhioHealth Campus

Located near OhioHealth, ample parking, and pylon signage available.

Pickerington, OH 43147

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Hebron Office/Warehouse with Highway Access

$9 SF/Yr

19,557 SF

Hebron Office/Warehouse with Highway Access

19,560 SF office/warehouse with dock, drive-in door, and highway access.

700 O'neill Dr, Hebron, OH 43025

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$0.24 SF/Yr

30,000 SF

Regus Cincinnati Office Suites

Flexible Workspace Solutions in Hebron

0 Cincinnati/Northen Kentucky International Airport, Hebron, OH 41048

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Explore Similar Spaces for Sale in Lancaster, OH

Consider Similar Space for Sale. We found 5 Spaces in Nearby Locations matching your search parameters.

$324,900

0.24 Acres

Lancaster Mixed-Use Opportunity

Versatile mixed-use building in Lancaster's thriving downtown corridor.

846 E Main St, Lancaster, OH 43130

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Lancaster Medical Office Investment Opportunity

$2,650,000

9,954 SF

Lancaster Medical Office Investment Opportunity

Single-tenant medical office building leased through 2032.

1781 Countryside Dr, Lancaster, OH 43130

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Charming Three-Story Commercial/Residential Property

$219,900

1,410 SF

Charming Three-Story Commercial/Residential Property

Versatile property with original features, suitable for office or residential.

324 E Main St, Lancaster, OH 43130

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$500,000

3,914 SF

Office Building Near Downtown

3,914 SF office building, ample parking, monument signage.

1973 E Main St, Lancaster, OH 43130

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$500,000

3,914 SF

Office Building Near Downtown Lancaster

3,914 SF office building with ample parking and signage.

1941 E Main St, Lancaster, OH 43130

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Lancaster, OH Office Properties & Spaces Leasing Opportunities Market Analysis

Explore Office Properties & Spaces leasing options in Lancaster, OH with 13 listings featured on our commercial real estate exchange. The current inventory includes 6,576,993,720 square feet of properties with an estimated lease value of $356 /Mo.

Estimated lease rates for Office Properties & Spaces in Lancaster, OH begin at $4 SF/Yr, with an average of $50 SF/Yr and extend to $168 SF/Yr.

Lancaster, OH Office Properties & Spaces for Lease

Downtown Lancaster Second-Floor Office Space

Second-floor office space for lease in downtown Lancaster, Ohio.

Downtown Lancaster Office Suite For Rent

Prime office suite in downtown Lancaster, available March 1, 2026.

New Lancaster Office Space Available

East Main Street Office Space

Lancaster Medical Office Building

Lancaster Medical Office Building

Medical Office Building For Lease

Lancaster Office Space Available

Explore Office Properties & Spaces for Lease in Nearby Cities

Pickerington Office/Medical Building For Lease

Prime Location Near OhioHealth Campus

Hebron Office/Warehouse with Highway Access

Regus Cincinnati Office Suites

Explore Similar Spaces for Sale in Lancaster, OH

Lancaster Mixed-Use Opportunity

Lancaster Medical Office Investment Opportunity

Charming Three-Story Commercial/Residential Property

Office Building Near Downtown

Office Building Near Downtown Lancaster

Lancaster, OH Office Properties & Spaces Leasing Opportunities Market Analysis

Browse Office Properties & Spaces for Lease Near Lancaster, OH

Popular Searches in Lancaster, OH

Most Searched ZIP Codes in Lancaster, OH

Lancaster, OH Office Properties & Spaces for Lease

Downtown Lancaster Second-Floor Office Space

Second-floor office space for lease in downtown Lancaster, Ohio.

Downtown Lancaster Office Suite For Rent

Prime office suite in downtown Lancaster, available March 1, 2026.

New Lancaster Office Space Available

East Main Street Office Space

Lancaster Medical Office Building

Lancaster Medical Office Building

Medical Office Building For Lease

Lancaster Office Space Available

Explore Office Properties & Spaces for Lease in Nearby Cities

Pickerington Office/Medical Building For Lease

Prime Location Near OhioHealth Campus

Hebron Office/Warehouse with Highway Access

Regus Cincinnati Office Suites

Explore Similar Spaces for Sale in Lancaster, OH

Lancaster Mixed-Use Opportunity

Lancaster Medical Office Investment Opportunity

Charming Three-Story Commercial/Residential Property

Office Building Near Downtown

Office Building Near Downtown Lancaster

Lancaster, OH Office Properties & Spaces Leasing Opportunities Market Analysis

Browse Office Properties & Spaces for Lease Near Lancaster, OH

Popular Searches in Lancaster, OH

Most Searched ZIP Codes in Lancaster, OH

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