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    Defiance, OH Office Properties & Spaces for Lease

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    Historic Downtown Building Renovation
    Contact for pricing
    13,200 SF

    Historic Downtown Building Renovation

    300 Clinton St, Defiance, OH 43512

    Prime location for restaurant or office space in Defiance, OH.

    • "Main and Main" location at the busiest intersection in Defiance offering unparalleled visibility and high traffic.
    • Major renovation of a historic downtown building, blending character with modern amenities.
    • Main floor available to be built out for a restaurant, providing a customizable space for a food service business.
    • Potential for outdoor dining area, enhancing the restaurant's appeal.
    • Second and third floors available for office suites, offering flexible options for professional tenants.
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    Office/Retail Space with Utilities Included
    $350 / Mo

    Office/Retail Space with Utilities Included

    912 E 2Nd St, Defiance, OH 43512

    Office/retail space with handicap access, kitchenette, restrooms, and parking.

    • Includes all utilities.
    • Ample parking available.
    • Features a lobby space and kitchenette.
    • Offers handicap accessible side door.
    • Provides both rear and front access.
    Updated: Oct 29, 2025
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    Downtown Defiance Executive Office Space
    Contact for pricing
    14,400 SF

    Downtown Defiance Executive Office Space

    Historic building, 13,200 sq ft available

    300 Clinton St, Defiance, OH 43512
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    Based on your search, we've compiled 7 Potential Opportunities for your consideration. Besides 3 Active listings in Defiance, OH, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities

    Explore Office Properties & Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Retail, Medical, Office Space Available
    Contact for pricing
    978 SF

    Retail, Medical, Office Space Available

    978 SF space suitable for retail, medical, or office use.

    10130 Maysville Rd, Fort Wayne, IN 46835
    View details
    Commercial Building Near Elida Road
    $2,500 / Mo
    1 SF

    Commercial Building Near Elida Road

    2100 SF shop space with overhead doors and parking.

    3840 Elida Rd. Rear, Lima, OH 45807
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    Shop Space For Lease
    $2,500 / Mo

    Shop Space For Lease

    2100 sq ft shop space with overhead doors and parking.

    3840 Elida Rd, Lima, OH 45807
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    Fort Wayne Office Space Available
    $12 SF/Yr
    7,592 SF

    Fort Wayne Office Space Available

    Modern Office Suite, Stellhorn Crossing

    9071 Stellhorn Crossing Pkwy, Fort Wayne, IN 46815
    View details

    Defiance, OH Office Properties & Spaces Leasing Opportunities Market Analysis

    Explore Office Properties & Spaces leasing options in Defiance, OH with 3 listings featured on our commercial real estate exchange. The current inventory includes 1,202,256,000 square feet of properties with an estimated lease value of $0.00 SF/Yr.

    Estimated lease rates for Office Properties & Spaces in Defiance, OH begin at $0.00 SF/Yr, with an average of $0.00 SF/Yr and extend to $0.00 SF/Yr.
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    Most Searched ZIP Codes in Defiance, OH

    • 43512

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