Ypsilanti, MI Office Spaces for Rent & Lease

Updated: Oct 1

Freestanding Office Building

2307 Washtenaw Avenue, Ypsilanti, MI 48197

$36 SF/Yr

1,200 sqft 0.32 AC lot

1,200‑square‑foot standalone office building
0.32‑acre lot
Central air conditioning and forced‑air heat
Built in 1970; vinyl siding
Phone service available

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Updated: May 14

Third-Floor Office Unit

101 W Michigan Avenue, Ypsilanti, MI 48197

$24 SF/Yr

3,650 sqft 0.04 AC lot

Third‑floor walk‑up office unit
Large windows and high ceilings
Kitchenette and ADA bathroom
Brick building constructed in 1837
Forced‑air heating and fireplace

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Office Unit in Multi-Room Building

D2-61 N Huron St, Ypsilanti, MI 48197

$700/Mo

10,296 sqft

The space can be combined with another similarly sized room or paired with a smaller office in the same building.

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Office Unit with Combination Potential

61 N Huron Street D1, Ypsilanti, MI 48197

$875/Mo

465 sqft

The space may be leased with another office or paired with a similarly sized room in the building.

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Freestanding Office Building with Private Lot

2307 Washtenaw Rd, Ypsilanti, MI 48197

$35.50 SF/Yr

1,200 sqft

The standalone layout pairs a dedicated office building with its own lot.

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Small Office Unit with Private Restroom

2142 Washtenaw Ave, Ypsilanti, MI 48197

$20.87 SF/Yr

460 sqft

Efficient suite includes storage space, facade signage, and convenient front-door parking.

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Freestanding Office Building

2307 Washtenaw Ave, Ypsilanti, MI 48197

$35 SF/Yr

1,200 sqft

A standalone office property offers a private lot and convenient access along Washtenaw Avenue.

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Flexible Medical Office Suite

300-740 Emerick St, Ypsilanti, MI 48198

$1,750/Mo

1,500 sqft

Versatile suite size flexibility supports medical, wellness, and other professional services with convenient I-94 access.

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Professional Office Suite

3150 Packard, Ypsilanti, MI 48197

$1,200/Mo

800 sqft

Office unit in a multi-tenant building with reception, private offices, conference space, and on-site parking.

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Flexible Medical Office Suite

200-740 Emerick St, Ypsilanti, MI 48198

$1,250/Mo

1,000 sqft

Versatile professional suite suited for medical, wellness, or other client-service uses near I-94 access.

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Economical Office Space Available

3914 Bestech Dr |, Ypsilanti, MI 48197

$16 SF/Yr

2,500 sqft

Office space with free cubicle furniture and ample parking.

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Well-Appointed Office Space Available Now

101 W Michigan Avenue, Ypsilanti, MI 48197

$24 SF/Yr

1,200 sqft

1200 sq ft office space with dramatic views.

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Endcap Medical Office Space

1769 Washtenaw Rd, Ypsilanti, MI 48197

$3,000/Mo

2,000 sqft

Move-in-ready space supports office, medical, or retail use with NNN lease structure.

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Multi-Unit Office Building

61 N Huron St, Ypsilanti, MI 48197

$7.62-$95.24 SF/Yr

315 sqft

Flexible office suites with varied layouts, shared unisex restrooms, and utilities included aside from phone and internet.

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Office Suite with Three Offices

61 N Huron St Unit U1, Ypsilanti, MI 48197

$2,000/Mo

An upstairs workspace includes a generous entry area and two private bathrooms.

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Downtown Office Building

133 W Michigan Ave, Ypsilanti, MI 48197

$14 SF/Yr

16,000 sqft

Office building available for rent at 133 W Michigan Ave in Ypsilanti.

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Office Unit

61 N Huron Street D2, Ypsilanti, MI 48197

Contact for pricing

315 sqft

The unit may be leased on its own or combined with another office or similarly sized room in the building.

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Remodeled Medical Office Suite

1649 S Huron St, Ypsilanti, MI 48197

$16 SF/Yr

2,156 sqft

Configured with reception, exam, imaging, and physician office areas.

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Professional Office Space for Lease

1974 N Huron River Drive Ypsilanti, Ypsilanti, MI 48197

Contact for pricing

2,086 sqft

Office space for lease with natural light and scenic views.

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Office Unit With Private Restroom

2142B Washtenaw Avenue, Ypsilanti, MI 48197

Contact for pricing

460 sqft

Efficient professional suite with facade signage, convenient parking, and access to US-23 along Washtenaw Avenue.

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Renovated Historic Downtown Ypsilanti Space

50 N Huron Street, Ypsilanti, MI 48197

$20 SF/Yr

7,700 sqft 0.12 AC lot

Renovated 1850 SF space in historic downtown Ypsilanti.

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Industrial Land with Office Building

2830 E Michigan Ave, Ypsilanti, MI 48198

Contact for pricing

5.07 AC lot

Industrial land offering 475' of frontage on E Michigan Ave with 1,160 sf of office space on site.

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Renovated Office Suite For Rent

265 S HARRIS Rd Bldg B, Ste 208, Ypsilanti, MI 48198

$525/Mo

1.37 AC lot

Recently renovated office suite available for lease near I-94.

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Move-in Ready Medical/Office Condo

3145 Clark Rd, Ypsilanti, MI 48197

$550,000

4,000 sqft

Well-configured condo near Trinity Health Hospital and local colleges.

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Ypsilanti, MI Office Spaces Lease Rates & Market Statistics

Browse 23 Office Spaces for lease in Ypsilanti, MI on Realmo, a commercial real estate marketplace serving the Ypsilanti area. The current inventory totals 56,503 square feet of properties — an average of ~2,450 SF per listing.

Asking lease rates for Office Spaces in Ypsilanti start at $7.62 SF/Yr, average $25.40 SF/Yr, and reach $95.24 SF/Yr at the top of the market. That's a 12x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. At $25.40 SF/Yr, the local average runs 18% above Michigan's state average of $21.62 SF/Yr.

Ypsilanti accounts for 16% of the 146 office spaces currently available across Washtenaw County, where nearby markets include Ann Arbor and Dexter. By space type, the market includes 17 office units, 5 medical office space listings and 5 office buildings — medical office space options typically offer the lowest entry point, while office buildings command the highest rates.