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Wayne, PA Office Buildings for Lease

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Main Line Office Opportunity
$5,279 / Mo

Main Line Office Opportunity

528 E Lancaster Ave, Wayne, PA 19087

Freestanding office building with frontage on Lancaster Avenue.

  • Prominent Lancaster Avenue frontage with pylon and building signage for HIGH VISIBILITY.
  • Convenient location: short walk to Paoli‑Thorndale Train Line, Giant supermarket, and local banks.
  • Ample parking with front and rear entries for easy access.
  • Well‑equipped office space: conference room, private offices, open work area, storage, kitchenette, and two bathrooms.
  • Easy access to major highways: I‑76, I‑476, PA Turnpike, Routes 202, 422, and 3.
Updated: Dec 10, 2025
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Chesterbrook Premier HQ Office Sublease
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233,120 SF

Chesterbrook Premier HQ Office Sublease

1500-1550 Liberty Ridge Dr, Wayne, PA 19087

Sublease opportunity in Chesterbrook, Wayne, PA, offering premier office space.

  • Premier HQ Office Space
  • Located in Chesterbrook
  • Sublease Opportunity for office space
  • HQ Office available
  • Additional Property Details Available
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Based on your search, we've compiled 9 Potential Opportunities for your consideration. Besides 2 Active listings in Wayne, PA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 3 Properties for Sales.

Explore Office buildings for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Renovated Class A Office Building
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15,769 SF

Renovated Class A Office Building

Four-story office building with commuter-friendly location and shuttle service.

200 N Warner Rd, King of Prussia, PA 19406
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Office Space in Chesterbrook
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41,670 SF

Office Space in Chesterbrook

Office space for lease in Chesterbrook, Pennsylvania with ample parking.

965 Chesterbrook Blvd, Berwyn, PA 19312
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Class A Office Space Available
Contact for pricing
21,235 SF

Class A Office Space Available

Energy-efficient office space with on-site amenities in Berwyn, PA.

1160 W Swedesford Rd, Berwyn, PA 19312
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Class A Office Space Available
Contact for pricing
23,358 SF

Class A Office Space Available

Luxury office building with modern amenities in King of Prussia.

640 Freedom Business Ctr Dr, King of Prussia, PA 19406
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Explore Similar Spaces for Sale in Wayne, PA

Consider Similar Space for Sale. We found 3 Spaces in Nearby Locations matching your search parameters.

Single-User Office Building in Wayne
$1,499,000
0.18 Acres

Single-User Office Building in Wayne

5,775 SF office building with modern finishes and exposed brick.

232 Conestoga Rd, Wayne, PA 19087
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Chesterbrook Corporate Center Office Building
Contact for pricing
10,726 SF

Chesterbrook Corporate Center Office Building

Meticulously maintained office building in Chesterbrook Corporate Center.

965 Chesterbrook Blvd, Chesterbrook, PA 19087
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Wayne Office Building For Sale
$1,600,000
7,600 SF

Wayne Office Building For Sale

Two-story office building in Wayne with Route 30 exposure.

418 E Lancaster Ave, Wayne, PA 19087
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Wayne, PA Office buildings Leasing Opportunities Market Analysis

Explore Office buildings leasing options in Wayne, PA with 5 listings featured on our commercial real estate exchange. The current inventory includes 10,154,707,200 square feet of properties with an estimated lease value of $0.00 SF/Yr.

Estimated lease rates for Office buildings in Wayne, PA begin at $0.00 SF/Yr, with an average of $0.00 SF/Yr and extend to $0.00 SF/Yr.
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