East Syracuse, NY Office buildings for Rent & Lease

Updated: Jul 25

Flexible Office Building with Windows

6575 Kirkville Road, East Syracuse, NY 13057

$16.50 SF/Yr

3,306 sqft

7,000 SF office building built in 2005
Large floor‑to‑ceiling windows for natural light
Layout can be modified to meet tenant needs
Excellent access to I‑481 and I‑690
Signage available on Kirkville Road

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Updated: Nov 22, 2025

Class A Office Space Available

5015 Campuswood Drive, East Syracuse, NY 13057

$18.50 SF/Yr

54,392 sqft

Class A office suites available for lease.
Located in Pioneer Business Park with paths and ponds.
Visibility from I‑90.
Opportunity for building naming rights and exterior signage for a tenant occupying the entire third floor.
Conveniently located in proximity to Carrier Circle and I‑90/NYS Thruway Exit 35.

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New Class A Office Facility

5855 Widewaters Parkway, East Syracuse, NY

$20.95 SF/Yr

41,537 sqft

Proposed Class A office building for lease in East Syracuse.

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Based on your search, we've compiled 14 Potential Opportunities for your consideration. Besides 3 Active listings in East Syracuse, NY, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 7 Properties for Sales.

Office buildings for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Class A Office Suites Available

225 Greenfield Parkway, Liverpool, NY 13088

$17.95 SF/Yr

7,092 sqft

Modern office suites with ample natural light near major highways.

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Class A Office Building Suite

5794 Widewaters Pkwy, Syracuse, NY 13214

Contact for pricing

19,707 sqft

Class A office building offers ample on-site parking and approximately 20,000 SF available in Widewaters Office Park.

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Prestige Office Building

6712 Brooklawn Pkwy, Syracuse, NY 13211

Contact for pricing

2,910 sqft

Office building with excellent parking, first-class interior finishes, and full-height mahogany doors throughout.

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Class A Office Space Available

225 Greenfield Pkwy, Liverpool, NY 13088

Contact for pricing

3,305 sqft

Modern office suites with ample natural light and highway access.

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Similar Spaces for Sale in East Syracuse, NY

Consider Similar Space for Sale. We found 7 Spaces matching your search parameters.

Standalone Office Building with Open Plan

6010 Drott Drive, East Syracuse, NY 13057

$799,000

6,000 sqft 0.78 AC lot

Adaptable office property with high ceilings, flexible interiors, and an industrial park setting.

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Class A Office Building

6611 Manlius Center Road, East Syracuse, NY 13057

$13,000,000

45,450 sqft 2.30 AC lot

Net leased office building with bank branch and lower level.

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Corporate Office and Flex Building

6706 Collamer Rd, East Syracuse, NY 13057

Contact for pricing

22,779 sqft 4.29 AC lot

Signature office building on 4.29 acres with a flexible plan, built in 2020, plus hi-bay testing space.

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Multi-Tenant Office Building

6007 Fairlakes Road, East Syracuse, NY 13057

Contact for pricing

32,406 sqft

Multi-tenant office property with leased space and 2016 roof and HVAC improvements.

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Two-Story Flex Office Facility

6005 Fair Lakes Road, East Syracuse, NY 13057

Contact for pricing

109,960 sqft

Well-maintained two-story office and open work areas with multiple office clusters, conference rooms, and loading capability.

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Free-Standing Medical Office Building

5844 Widewaters Pkwy, East Syracuse, NY 13057

Contact for pricing

3,812 sqft

Free-standing 3,812 SF single-user medical office building with immediate access to key East Syracuse roadways.

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Class A Office Building

34 Aspen Park Blvd, East Syracuse, NY

Contact for pricing

25,000 sqft 6.84 AC lot

25,000 SF Class A office building in growing area.

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East Syracuse, NY Office buildings Lease Rates & Market Statistics

Explore 3 Office buildings for lease in East Syracuse, NY on Realmo, a commercial real estate exchange covering the East Syracuse area. The current inventory totals 99,235 square feet of properties.

Office buildings lease rates in East Syracuse range from $16.50 SF/Yr at the entry level to $20.95 SF/Yr at the top of the market, averaging $18.65 SF/Yr. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. At $18.65 SF/Yr, the local average runs 50% below New York's state average of $37.09 SF/Yr.

East Syracuse accounts for 15% of the 20 office buildings currently available across Onondaga County, where nearby markets include Syracuse and Liverpool. Office buildings are one of the more limited space types in East Syracuse, with just 3 listings currently available — a scarcity worth factoring into lease negotiations. Tenants comparing options may also consider Office Units (10 listings) elsewhere in the East Syracuse market.

East Syracuse, NY Office Buildings for Lease

6575 Kirkville Road, East Syracuse, NY 13057

5015 Campuswood Drive, East Syracuse, NY 13057

5855 Widewaters Parkway, East Syracuse, NY