East Syracuse, NY Office buildings for Rent & Lease

Updated: Nov 22, 2025

Class A Office Space Available

5015 Campuswood Drive, East Syracuse, NY 13057

$18.50 SF/Yr

54,392 sqft

Class A office suites available for lease.
Located in Pioneer Business Park with paths and ponds.
Visibility from I‑90.
Opportunity for building naming rights and exterior signage for a tenant occupying the entire third floor.
Conveniently located in proximity to Carrier Circle and I‑90/NYS Thruway Exit 35.

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Updated: Jul 23

Flexible Office Building with Windows

6575 Kirkville Rd, East Syracuse, NY 13057

Contact for pricing

3,306 sqft

7,000 SF office building built in 2005
Large floor‑to‑ceiling windows for natural light
Layout can be modified to meet tenant needs
Excellent access to I‑481 and I‑690
Signage available on Kirkville Road

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New Class A Office Facility

5855 Widewaters Parkway, East Syracuse, NY

$20.95 SF/Yr

41,537 sqft

Proposed Class A office building for lease in East Syracuse.

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Office Building with Three Patios

6700 Kirkville Rd, E Syracuse, NY 13057

Contact for pricing

565 sqft

Medical and professional office suites are located on a corner just off I-481, Exit 5.

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Based on your search, we've compiled 15 Potential Opportunities for your consideration. Besides 4 Active listings in East Syracuse, NY, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 7 Properties for Sales.

Office buildings for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Class A Office Building Suite

5794 Widewaters Pkwy, Syracuse, NY 13214

Contact for pricing

20,000 sqft

Class A office building offers ample on-site parking and approximately 20,000 SF available in Widewaters Office Park.

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Office Building with Conference Room Views

4100 Medical Center Dr, Fayetteville, NY 13066

Contact for pricing

3,861 sqft

Office building with a large conference/event room, 24-hour access, and ample free outdoor parking.

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Office Building with Loading Dock

4100 Medical Center Dr, Fayetteville, NY 13066

Contact for pricing

901 sqft

Office building with 24-hour access, large common conference/event room, and loading dock with freight elevator.

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Prestige Office Building

6712 Brooklawn Pkwy, Syracuse, NY 13211

Contact for pricing

Office building with excellent parking, first-class interior finishes, and full-height mahogany doors throughout.

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Similar Spaces for Sale in East Syracuse, NY

Consider Similar Space for Sale. We found 7 Spaces matching your search parameters.

Class A Office Building

6611 Manlius Center Road, East Syracuse, NY 13057

$13,000,000

45,450 sqft 2.30 AC lot

Net leased office building with bank branch and lower level.

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Two-Story Flex Office Facility

6005 FAIR LAKES RD, East Syracuse, NY 13057

Contact for pricing

109,960 sqft

Well-maintained two-story office and open work areas with multiple office clusters, conference rooms, and loading capability.

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Free-Standing Medical Office Building

5844 Widewaters Pkwy, East Syracuse, NY 13057

Contact for pricing

3,812 sqft

Free-standing 3,812 SF single-user medical office building with immediate access to key East Syracuse roadways.

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Net-Leased Office Building with Bank Branch

6611 Manlius Center Rd, E Syracuse, NY 13057

Contact for pricing

45,450 sqft

Class A net-leased office building with an occupied lower level and a ground-floor bank branch with three drive-thru lanes.

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Modern Class A Office Building

5062 Brittonfield Pkwy, East Syracuse, NY

Contact for pricing

40,625 sqft 4.81 AC lot

40,625 SF office building ideal for medical or conventional use.

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Multi-Tenant Office Building

6007 Fair Lakes Rd, East Syracuse, NY 13057

Contact for pricing

32,406 sqft

Multi-tenant office property with leased space and 2016 roof and HVAC improvements.

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Class A Office Building

34 Aspen Park Blvd, East Syracuse, NY

Contact for pricing

25,000 sqft 6.84 AC lot

25,000 SF Class A office building in growing area.

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East Syracuse, NY Office buildings Market Trends and Statistics

Explore Office buildings leasing options in East Syracuse, NY with 4 listings featured on our commercial real estate exchange. The current inventory includes 99,800 square feet of properties with an estimated lease value of $39.45.

Estimated lease rates for Office buildings in East Syracuse, NY begin at $18.50 SF/Yr, with an average of $19.73 SF/Yr and extend to $20.95 SF/Yr.