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    Saint Helena Island, SC Mixed-use Properties for Sale

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    Highway 21 Mixed-Use Opportunity
    $650,000
    0.47 Acres

    Highway 21 Mixed-Use Opportunity

    2123 Sea Island Pkwy, Saint Helena Island, SC 29920

    Versatile property on Harbor Island with Highway 21 frontage.

    • Prime Hwy‑21 frontage on Harbor Island with high visibility.
    • Versatile 3,520 SF three‑story building, ideal for office, live‑work, residential, or short‑term rental.
    • Located near Fripp Island, Harbor Island, and Dataw Island.
    • Gorgeous Lowcountry water and marsh views.
    • Includes a 1,000 SF utility shed and paved parking lot.
    Last Update: Oct 22
    View details
    Based on your search, we've compiled 5 Potential Opportunities for your consideration. Besides 1 Active listings in Saint Helena Island, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Pad-Ready Mixed-Use Development Opportunity
    $52,000
    0.03 Acres

    Pad-Ready Mixed-Use Development Opportunity

    Mixed-use development lots in upscale Celadon community with completed infrastructure.
    18 Celadon Dr, Beaufort, SC 29907
    View details
    Commercial Property Near Downtown Beaufort
    $3,000,000
    1.48 Acres

    Commercial Property Near Downtown Beaufort

    Mixed-use property with apartments and commercial spaces near downtown Beaufort.
    81 A Sea Is Pkwy, Beaufort, SC 29907
    View details
    Turnkey Restaurant Investment Opportunity
    $1,499,000
    0.30 Acres

    Turnkey Restaurant Investment Opportunity

    Prime Lowcountry real estate, updated restaurant with upstairs living unit.
    925 10Th St, Port Royal, SC 29935
    View details
    Prime Corner Lot in Port Royal
    $950,000
    0.23 Acres

    Prime Corner Lot in Port Royal

    0.23-acre mixed-use parcel in vibrant Port Royal's T4-Urban Center.
    1008 Paris Ave, Port Royal, SC 29935
    View details

    Saint Helena Island, SC Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 1 mixed-use properties for sale in Saint Helena Island, SC on our real estate platform. These investment opportunities span a total of 20,473 square feet of properties for sale, with an estimated market value of $650,000.

    Prices for multi use buildings in Saint Helena Island, SC start at $650,000, averaging $650,000, and reaching up to $650,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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