Greenville, PA Mixed-use properties for sale

Updated: Nov 5, 2025

Greenville Commercial Property with Veterinary

409 E JAMESTOWN Road, Greenville, PA 16125

$615,000

4,211 sqft 3.46 AC lot

Established veterinary clinic with secure lease provides consistent rental income.
Expansive 4‑bedroom, 2.5‑bath home on 3.46 acres.
Large barn with 9 stalls and indoor arena.
Potential rental income from horse stalls, fenced pastures, and stables.
Unique opportunity combining residential living with commercial income.

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Updated: Nov 5, 2025

Horse Facility with Indoor Arena

409 E JAMESTOWN Road, Greenville, PA 16125

$615,000

2,792 sqft 3.46 AC lot

3.46‑acre horse property with a large barn and indoor arena
Main home features 4 bedrooms and 2.5 baths with a large living room and open kitchen
Barn includes 9 stalls plus indoor arena space
On‑site well‑established veterinary clinic secured by a solid lease
Well water and septic tank

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Mixed-Use Property With Apartments

28 Shenango St, Greenville, PA 16125

$180,000

0.19 AC lot

Four apartments, a karate studio, garage storage, and side parking occupy this historic Greenville commercial property.

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Tudor-Style Mixed-Use Building

281 Main, Greenville, PA 16125

$179,000

Commercial and residential components support professional use below with two private-entry apartments upstairs.

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Based on your search, we've compiled 10 Potential Opportunities for your consideration. Besides 4 Active listings in Greenville, PA, we suggest exploring several alternatives: 4 properties in Nearby Cities, plus 2 Land Listings that present a potential for development.

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Mixed-Use Property with Driving Range

3917 MAIN Street, Adamsville, PA 16110

$89,900

2,740 sqft 0.24 AC lot

Commercial space, residential accommodation, and detached garage combine in a flexible two-level property.

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Mixed-Use Property with Pizza Shop

1837 STATE HIGHWAY 285, Espyville, PA 16424

$259,900

3,934 sqft 0.26 AC lot

Includes three rental units and three garage spaces alongside seasonal food-service operations.

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Mixed-Use Property with Pizza Shop

1837 STATE HIGHWAY 285, Espyville, PA 16424

$259,900

3,934 sqft 0.26 AC lot

Seasonal food-service operation accompanied by three residential rental units and three garage spaces.

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Mixed-Use Property with Driving Range Unit

3917 MAIN Street, Adamsville, PA 16110

$89,900

2,740 sqft 0.24 AC lot

Two-level mixed-use building with an indoor driving range commercial unit and a 3-bedroom apartment above.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Commercial Land Across From Airport

1440 Youngstown Kingsville Road, Vienna, OH 44473

$229,000

23.24 AC lot

C2-zoned commercial land with public water and sewer available for large-scale development planning.

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Commercial Development Land

Mahoning Avenue, Champion, OH 44483

$1,650,000

100.87 AC lot

Vacant commercial land with public water, public sewer, and access to multiple regional transportation routes.

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Greenville, PA Mixed-Use Properties Market Trends and Statistics

Explore 4 mixed-use properties for sale in Greenville, PA, showcased through 4 active listings on our real estate platform. These investment opportunities span a total of 7,003 square feet of properties for sale, with an estimated market value of $1,589,000.

Sale prices for multi use buildings in Greenville, PA start at $179,000, averaging $397,250, and reaching up to $615,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

Neighborhood	Average Price
16125	$412.3K

Neighborhood

Average Price

16125

$412.3K