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    Joplin, MO Mixed-use Properties for Sale

    20 results
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    Route 66 Commercial Opportunity
    $200,000
    1,984 SF

    Route 66 Commercial Opportunity

    1209 W 7Th St, Joplin, MO 64801

    Unique commercial space with live-work potential on Route 66.

    • Prime location on historic Route 66, ideal for high‑traffic business.
    • Unique layout with hidden doors and secret passages, creating a memorable atmosphere.
    • Includes an additional lot for parking and a spacious patio, enhancing customer accessibility and outdoor space.
    • Private upstairs apartment with full bathroom, suitable for live‑work arrangement or VIP suite.
    • Versatile building suitable for various business concepts: speakeasy, themed restaurant, retail, showroom, event venue, or office.
    Updated: Feb 11
    View details
    Versatile Mixed-Use Commercial Property
    $850,000
    42,907 SF

    Versatile Mixed-Use Commercial Property

    902 E 4Th St, Joplin, MO 64801

    42,907 SF mixed-use property with office and warehouse space.

    • 42,907 SF mixed‑use commercial property with office and warehouse space.
    • Value‑add opportunity through strategic renovations, improved occupancy, or lease optimization.
    • Adjacent land available for parking or future development.
    • 2nd floor office suites with expansive skylights providing natural light.
    • Rear‑loading docks for warehouse and distribution tenants.
    Updated: Nov 26, 2025
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    Versatile Commercial Building on Route 66
    $1,798,500
    15,000 SF

    Versatile Commercial Building on Route 66

    Adaptable commercial building in downtown Joplin with high visibility.

    204 East 7Th St, Joplin, MO 64801
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    Prime Commercial Property on Main
    Pending
    $4,100,000
    43,053 SF

    Prime Commercial Property on Main

    4.14-acre commercial property with showroom, apartment, and high visibility.

    5014 S Main St, Joplin, MO 64804
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    Historic Mixed-Use Building, Joplin
    $299,000
    5,700 SF

    Historic Mixed-Use Building, Joplin

    Prime downtown location with retail, commercial, and residential potential.

    405 S Main St, Joplin, MO 64801
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    Versatile Land Parcel, Joplin, MO
    $166,000
    1.00 Acre

    Versatile Land Parcel, Joplin, MO

    Adaptable land parcel suitable for various development projects in Joplin.

    2830 S Mc Clelland Blvd, Joplin, MO 64804
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    Versatile Land Parcel, Joplin, MO
    $166,000
    1.00 Acre

    Versatile Land Parcel, Joplin, MO

    Adaptable land parcel suitable for various development projects.

    2830 S Mc Clelland Blvd, Joplin, MO 64804
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    Versatile Live-Work Property in Joplin
    $1,150,000
    5,200 SF

    Versatile Live-Work Property in Joplin

    4,000 sq ft shop with 1,200 sq ft living space.

    4445 E Cypress Rd, Joplin, MO 64801
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    Joplin Commercial Lot For Sale
    $175,000
    0.63 Acres

    Joplin Commercial Lot For Sale

    Highly visible 0.63 acre commercial lot with development potential.

    2202 S Connecticut Ave, Joplin, MO 64804
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    Versatile Land Parcel, Joplin, MO
    Pending
    $284,500
    2.00 Acres

    Versatile Land Parcel, Joplin, MO

    Adaptable land parcel suitable for various development projects.

    2830 S Mc Clelland Blvd, Joplin, MO 64804
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    Historic Mixed-Use Property in Joplin
    $190,000
    15,000 SF

    Historic Mixed-Use Property in Joplin

    15,000 sq ft historic property in Joplin's Historic District.

    830 Main St, Joplin, MO 64801
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    Downtown Joplin Mixed-Use Property
    $2,200,000
    17,940 SF

    Downtown Joplin Mixed-Use Property

    Premier mixed-use property with luxury apartments and commercial spaces.

    702 S Wall Ave, Joplin, MO 64801
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    Joplin Commercial Property with Versatility
    $145,000
    1,252 SF

    Joplin Commercial Property with Versatility

    Commercial-zoned property suitable for business, investment, or live/work use.

    1317 S Schifferdecker Ave, Joplin, MO 64801
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    Historic Joplin Landmark For Sale
    $500,000

    Historic Joplin Landmark For Sale

    Redevelopment opportunity in thriving C-1 commercial zone.

    2008 S Sergeant Ave, Joplin, MO 64804
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    Joplin Retail & Warehouse Opportunity
    $2,600,000
    30,200 SF

    Joplin Retail & Warehouse Opportunity

    High-Visibility Commercial Property, Missouri

    2920 Range Line Rd, Joplin, MO 64804
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    Joplin Warehouse/Office Space
    $2,200,000
    32,750 SF

    Joplin Warehouse/Office Space

    32,750 SF Mixed-Use Property, Vacant

    5571 Main Street Rd, Joplin, MO 64801
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    Joplin MO Industrial Flex Space
    $3,525,000
    30,000 SF

    Joplin MO Industrial Flex Space

    30,000 SF Multi-Tenant Office/Warehouse

    4830 32Nd St, Joplin, MO 64804
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    Joplin Union Depot: Redevelopment Opportunity
    Contact for pricing
    22,640 SF

    Joplin Union Depot: Redevelopment Opportunity

    Historic Train Station, 22,640 sq ft

    205 Main St, Joplin, MO 64801
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    Joplin MO Commercial Land & Barn
    $397,500
    4.00 Acres

    Joplin MO Commercial Land & Barn

    4-Acre Multi-Use Property, Great Potential

    4014 7Th St, Joplin, MO 64801
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    WestPointe Centre: Joplin Investment
    $1,800,000
    20,185 SF

    WestPointe Centre: Joplin Investment

    Thriving Mixed-Use Property on Route 66

    2207 7Th St, Joplin, MO 64801
    View details
    Based on your search, we've compiled Potential Opportunities for your consideration. Besides 20 Active Listings in Joplin, MO, we suggest to view alternatives - similar 52 Off-Market properties to explore as potential leads.

    Explore Off-Market Properties in Joplin, MO

    Consider similar Off-Market properties in Joplin, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    2207 7Th St

    2207 7Th St

    Mixed-use properties • 20,185 SF
    Value Estimation by Request
    2207 7Th St, Joplin, MO 64801
    View details
    2573 Range Line Rd

    2573 Range Line Rd

    Restaurants • 1.18 Acres
    Value Estimation by Request
    2573 Range Line Rd, Joplin, MO 64801
    View details
    14529 Hwy Ff

    14529 Hwy Ff

    OFFICE/RESIDENTIAL (MIXED USE) • 1,902 SF
    Value Estimation by Request
    14529 Hwy Ff, Joplin, MO 64804-7855
    View details
    Joplin, MO 64804

    Joplin, MO 64804

    OFFICE/RESIDENTIAL (MIXED USE) • 784 SF
    Value Estimation by Request
    Joplin, MO 64804
    View details

    Joplin, MO Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 72 mixed-use properties for sale in Joplin, MO, showcased through 20 active listings on our real estate platform. These investment opportunities span a total of 21,743,846 square feet of properties for sale, with an estimated market value of $20,669,000.

    Sale prices for multi use buildings in Joplin, MO start at $145,000, averaging $439,765, and reaching up to $4,100,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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