Chillicothe, MO Mixed-use properties for sale

Updated: Jul 10

Turnkey Restaurant with Residential Home

425 & 437 Cherry Street, Chillicothe, MO 64601

$475,000

4,848 sqft 0.51 AC lot

3,888 SF turnkey restaurant with indoor and outdoor seating and three half bathrooms
Kitchen includes a brand‑new 10‑foot Hood Mart commercial hood system
Attached 960 SF, two‑story residence built in 1900 with three bedrooms and two bathrooms
2025 remodel: new roof, windows, doors, flooring, and updated electrical and plumbing systems
Exterior central air conditioning unit serving the south building replaced in 2025

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Updated: May 19

Downtown Restaurant Buildings

607 & 609 Jackson Street, Chillicothe, MO 64601

$315,000

0.14 AC lot

Approximately 3,716 square feet of restaurant space
Additional 1,220 square feet above 607 Jackson Street
Includes walk‑in cooler, steam table, prep table, and stove
Tables and booths included with the restaurant layout
Two commercial buildings at 607 & 609 Jackson Street

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Three-Story Mixed-Use Building

614 Washington Street, Chillicothe, MO 64601

$155,900

0.10 AC lot

The building combines occupied office and retail spaces with unfinished upper-level areas suited to redevelopment.

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Three-Story Mixed-Use Building

614 Washington Street, Chillicothe, MO 64601

$155,900

13,440 sqft

Seven occupied ground-floor spaces support office and retail use, while the upper levels remain unfinished and open.

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Based on your search, we've compiled 15 Potential Opportunities for your consideration. Besides 4 Active listings in Chillicothe, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 7 Off-Market properties to explore as potential leads

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Mixed-Use Restaurant Property

124 W Grand Street, Gallatin, MO 64640

$145,000

0.07 AC lot

Brick commercial building combines a restaurant-retail level with second-floor residential quarters.

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Mixed-Use Building with Apartment

205 N Main St, Gallatin, MO 64640

$94,900

6,300 sqft

Two-level property combines office, retail, storage, warehouse, and residential space with separate entrances.

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Mixed-Use Building with Flexible Layout

108 E Kelling Avenue, Waverly, MO 64096

$74,500

0.07 AC lot

As-is property with central air, forced-air heating, and a layout adaptable to retail, office, or service use.

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Mixed-Use Building with Restroom

108 E Kelling Avenue, Waverly, MO 64096

$74,500

0.07 AC lot

Flexible commercial space with a private restroom, on-street parking, and water available.

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Off-Market Properties in Chillicothe, MO

Consider similar Off-Market properties in Chillicothe, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

OFFICE/RESIDENTIAL (MIXED USE)

610 Clay St, Chillicothe, MO 64601-2607

Estimated value:

$145,000

1,375 sqft 0.08 AC lot

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OFFICE/RESIDENTIAL (MIXED USE)

818 Washington St, Chillicothe, MO 64601-2232

Estimated value:

$275,000

2,900 sqft 0.15 AC lot

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OFFICE/RESIDENTIAL (MIXED USE)

817 Washington St, Chillicothe, MO 64601

Estimated value:

$150,000

1,677 sqft 0.10 AC lot

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OFFICE/RESIDENTIAL (MIXED USE)

609 Clay St, Chillicothe, MO 64601-2606

Estimated value:

$235,000

5,280 sqft 0.31 AC lot

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OFFICE/RESIDENTIAL (MIXED USE)

602 Jackson St, Chillicothe, MO 64601-2244

Estimated value:

$180,000

2,834 sqft 0.06 AC lot

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OFFICE/RESIDENTIAL (MIXED USE)

913 Webster St, Chillicothe, MO 64601-2241

Estimated value:

$225,000

4,575 sqft 0.15 AC lot

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OFFICE/RESIDENTIAL (MIXED USE)

610 Jackson St, Chillicothe, MO 64601-2244

Estimated value:

$230,000

4,884 sqft 0.06 AC lot

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Chillicothe, MO Mixed-Use Properties Market Trends and Statistics

Explore 11 mixed-use properties for sale in Chillicothe, MO, showcased through 4 active listings on our real estate platform. These investment opportunities span a total of 18,288 square feet of properties for sale, with an estimated market value of $1,101,800.

Sale prices for multi use buildings in Chillicothe, MO start at $155,900, averaging $275,450, and reaching up to $475,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

Neighborhood	Average Price
64601	$276.5K

Neighborhood

Average Price

64601

$276.5K

Featured Chillicothe Real Estate Agencies

Realmo connects you with licensed Chillicothe CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

United Country Graham Agency, LLC

801 Washington St. Chillicothe, MO

Phone: (660) 646-7653

Chillicothe, MO Mixed-use Properties for Sale

425 & 437 Cherry Street, Chillicothe, MO 64601

607 & 609 Jackson Street, Chillicothe, MO 64601

614 Washington Street, Chillicothe, MO 64601

614 Washington Street, Chillicothe, MO 64601