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    Safety Harbor, FL Mixed-use Properties for Sale

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    Historic Mixed-Use Property on Main
    Pending
    $3,999,000
    9,605 SF

    Historic Mixed-Use Property on Main

    454 Main St, Safety Harbor, FL 34695

    Charming mixed-use property in Safety Harbor's vibrant downtown.

    • Prime Main Street Location: 155 feet of frontage on a nationally recognized, vibrant Main Street.
    • Income‑Generating Property: Operating as a top‑rated Airbnb Superhost with (8) turnkey apartment units.
    • Flexible Zoning: Zoned Main Street Marketplace (MSM), supporting a wide variety of uses.
    • Significant Square Footage: Features 9,605 SF under roof, 2,599 SF of balcony space, and 2,983 SF of retail space.
    • Recent Capital Improvements: Includes a new roof (2020) and new HVAC with ductwork (2023) in the retail space.
    Updated: Dec 23, 2025
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    Safety Harbor Mixed-Use Property
    $1,873,500
    3,895 SF

    Safety Harbor Mixed-Use Property

    1055 Philippe Pkwy, Safety Harbor, FL 34695

    Prime location, endless possibilities. $1.87M

    • Safety Harbor, FL
    • $1,873,500
    • Virtual Tour Available (link provided)
    • Safety Harbor, FL, 1‑acre lot
    • Existing Assisted Living Facility (ALF) with redevelopment potential as office space, bed & breakfast, multifamily, or day/med spa.
    Updated: Dec 11, 2024
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    Based on your search, we've compiled 17 Potential Opportunities for your consideration. Besides 2 Active listings in Safety Harbor, FL, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 11 Off-Market properties to explore as potential leads

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Prime Clearwater Restaurant Site
    $550,000
    17,000 SF

    Prime Clearwater Restaurant Site

    17,000 SF Vacant Restaurant Space

    1631 Gulf To Bay Blvd, Clearwater, FL 33755
    View details
    Renovated Mixed-Use Property in Dunedin
    $950,000
    3,600 SF

    Renovated Mixed-Use Property in Dunedin

    Versatile property with office and warehouse space near downtown.

    620 Union St, Dunedin, FL 34698
    View details
    Dunedin Downtown Commercial Opportunity
    $3,250,000
    2,308 SF

    Dunedin Downtown Commercial Opportunity

    Prime 0.60-acre site in Dunedin's Downtown Core zoning district.

    458 Scotland St, Dunedin, FL 34698
    View details
    Downtown Clearwater Redevelopment Opportunity
    $4,420,000

    Downtown Clearwater Redevelopment Opportunity

    Rare 2-acre assemblage in Clearwater's urban core.

    1214-1242 Cleveland St, Clearwater, FL 33755
    View details

    Explore Off-Market Properties in Safety Harbor, FL

    Consider similar Off-Market properties in Safety Harbor, FL. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    134 5th S Ave

    134 5th S Ave

    OFFICE/RESIDENTIAL (MIXED USE) • 1,001 SF
    Value Estimation
    $1,430,000
    134 5th S Ave, Safety Harbor, FL 34695-4031
    View details
    308 Main St

    308 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 1,760 SF
    Value Estimation
    $1,775,000
    308 Main St, Safety Harbor, FL 34695-3645
    View details
    1055 Philippe Pkwy

    1055 Philippe Pkwy

    Retirement homes • 3,895 SF
    Value Estimation by Request
    1055 Philippe Pkwy, Safety Harbor, FL 34695
    View details
    231 2nd S St, Unit 101

    231 2nd S St, Unit 101

    STORE/OFFICE (MIXED USE) • 2,880 SF
    Value Estimation
    $1,225,000
    231 2nd S St, Safety Harbor, FL 34695-4004
    View details
    509 Main St

    509 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 4,196 SF
    Value Estimation
    $3,250,000
    509 Main St, Safety Harbor, FL 34695-3550
    View details
    454 Main St

    454 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 7,342 SF
    Value Estimation
    $1,585,000
    454 Main St, Safety Harbor, FL 34695-3663
    View details
    143 7th N Ave

    143 7th N Ave

    OFFICE/RESIDENTIAL (MIXED USE) • 800 SF
    Value Estimation
    $1,145,000
    143 7th N Ave, Safety Harbor, FL 34695-3538
    View details
    324 Main St

    324 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 3,680 SF
    Value Estimation
    $2,770,000
    324 Main St, Safety Harbor, FL 34695-3645
    View details
    125 5th N Ave

    125 5th N Ave

    OFFICE/RESIDENTIAL (MIXED USE) • 924 SF
    Value Estimation
    $1,600,000
    125 5th N Ave, Safety Harbor, FL 34695-3636
    View details
    201 Main St

    201 Main St

    OFFICE/RESIDENTIAL (MIXED USE) • 17,496 SF
    Value Estimation
    $16,805,000
    201 Main St, Safety Harbor, FL 34695-3608
    View details
    470 2nd N St

    470 2nd N St

    OFFICE/RESIDENTIAL (MIXED USE) • 3,630 SF
    Value Estimation
    $1,660,000
    470 2nd N St, Safety Harbor, FL 34695-3600
    View details

    Safety Harbor, FL Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 13 mixed-use properties for sale in Safety Harbor, FL on our real estate platform. These investment opportunities span a total of 123,480 square feet of properties for sale, with an estimated market value of $14,487,500.

    Sale prices for multi use buildings in Safety Harbor, FL start at $240,000, averaging $1,609,722, and reaching up to $3,999,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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