Add Listing
    For Sale
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Office
    1
    • Retail
    • Office
    • Residential Income
    • Restaurants
    • Industrial
    • Mixed-Use
    • Hospitality
    • Health Care
    • Sports & Entertainment
    • Land
    • Agricultural
    • Specialty
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Meet Realmo: The Largest Hub
    of Commercial Real     Estate in the US

    Over 1 million active listings and over 150 million property profiles

    Columbiana County, OH Medical Office Space for Sale

    Notify Me
    List
    Map
    Cleveland, OH Columbus, OH Cincinnati, OH
    Versatile Commercial Space in Salem
    $150,000
    0.10 Acres

    Versatile Commercial Space in Salem

    293 N Ellsworth Avenue, Salem, OH 44460

    Well-built commercial building with multiple potential uses in Salem, OH.

    • Prime location in the heart of the city.
    • Large parking lot, with an additional parking lot available.
    • Versatile space suitable for various uses (medical, retail, bar, etc.).
    • Option to purchase or lease the property.
    • Potential to be divided into one or two units.
    Updated: Mar 11
    View details
    Move-In Ready Medical Office Building
    $2,990,000
    18,000 SF

    Move-In Ready Medical Office Building

    750 E Park Ave, Columbiana, OH 44408

    Over 18,000 SF medical office in fantastic condition.

    • Over 18,000 square feet of office space, move‑in ready.
    • Building is in fantastic condition.
    • Formerly the Salem Regional Medical Center.
    • Located in Columbiana.
    • Deed restrictions apply to usage.
    Updated: Nov 11, 2025
    View details
    Based on your search, we've compiled 115 Potential Opportunities for your consideration. Besides 2 Active listings in Columbiana County, OH, we suggest exploring several alternatives: similar 109 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Mansfield Commercial Development Opportunity
    $120,000
    1.72 Acres

    Mansfield Commercial Development Opportunity

    1.72 acre parcel ideal for medical or professional office.

    1150 Aspira Ct, Mansfield, OH 44907
    View details
    Commercial Land in Mansfield, Ohio
    $130,000
    2.80 Acres

    Commercial Land in Mansfield, Ohio

    2.8 acres of commercial land suitable for development.

    1120 Aspira Ct., Mansfield, OH 44906
    View details
    Commercial Land in Mansfield, Ohio
    $85,000

    Commercial Land in Mansfield, Ohio

    Prime commercial land suitable for development in Mansfield, Ohio.

    1140 Aspira Ct., Mansfield, OH 44907
    View details
    Commercial Land on Route 13
    $650,000
    3.13 Acres

    Commercial Land on Route 13

    3.13 acres of commercial land with high traffic volume.

    Mt. Vernon Road, Newark, OH 43055
    View details

    Explore Off-Market Properties in Columbiana County, OH

    Consider similar Off-Market properties in Columbiana County, OH. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    2380 Sese Blvd Ste C

    2380 Sese Blvd Ste C

    MEDICAL BUILDING • 1,666 SF
    Value Estimation by Request
    2380 Sese Blvd Ste C, Salem, OH 44460-3477
    View details
    651 Fisher Ave

    651 Fisher Ave

    MEDICAL BUILDING • 2,394 SF
    Value Estimation by Request
    651 Fisher Ave, East Liverpool, OH 43920-1316
    View details
    2345 Pershing St

    2345 Pershing St

    MEDICAL BUILDING • 8,458 SF
    Value Estimation
    $3,295,000
    2345 Pershing St, Salem, OH 44460-3400
    View details
    2370 Sese Blvd

    2370 Sese Blvd

    MEDICAL BUILDING • 6,020 SF
    Value Estimation
    $570,000
    2370 Sese Blvd, Salem, OH 44460-3418
    View details
    139 Walnut St

    139 Walnut St

    MEDICAL BUILDING • 3,582 SF
    Value Estimation by Request
    139 Walnut St, East Palestine, OH 44413-1815
    View details
    48959 Calcutta Smithferry Rd

    48959 Calcutta Smithferry Rd

    MEDICAL BUILDING • 2,640 SF
    Value Estimation
    $580,000
    48959 Calcutta Smithferry Rd, East Liverpool, OH 43920-9637
    View details
    2360 Sese Blvd

    2360 Sese Blvd

    MEDICAL BUILDING • 1,488 SF
    Value Estimation by Request
    2360 Sese Blvd, Salem, OH 44460-3418
    View details
    48892 Calcutta Smithferry Rd

    48892 Calcutta Smithferry Rd

    MEDICAL BUILDING • 2,990 SF
    Value Estimation by Request
    48892 Calcutta Smithferry Rd, East Liverpool, OH 43920-9637
    View details
    320 Columbia St

    320 Columbia St

    MEDICAL BUILDING • 800 SF
    Value Estimation by Request
    320 Columbia St, Leetonia, OH 44431-1291
    View details
    23 Main St

    23 Main St

    MEDICAL BUILDING • 1,980 SF
    Value Estimation by Request
    23 Main St, Columbiana, OH 44408
    View details
    20 Parkview Dr

    20 Parkview Dr

    MEDICAL BUILDING • 2,384 SF
    Value Estimation by Request
    20 Parkview Dr, Columbiana, OH 44408-1000
    View details
    50410 State Rte 14

    50410 State Rte 14

    MEDICAL BUILDING • 2,511 SF
    Value Estimation by Request
    50410 State Rte 14, East Palestine, OH 44413-1025
    View details
    2376 Sese Blvd

    2376 Sese Blvd

    MEDICAL BUILDING • 1,488 SF
    Value Estimation by Request
    2376 Sese Blvd, Salem, OH 44460-3472
    View details
    49126 Calcutta Smithferry Rd

    49126 Calcutta Smithferry Rd

    MEDICAL BUILDING • 2,946 SF
    Value Estimation
    $765,000
    49126 Calcutta Smithferry Rd, East Liverpool, OH 43920-9001
    View details
    1100 Pennsylvania Ave

    1100 Pennsylvania Ave

    MEDICAL BUILDING • 2,764 SF
    Value Estimation by Request
    1100 Pennsylvania Ave, East Liverpool, OH 43920-3539
    View details
    40 Park Dr

    40 Park Dr

    MEDICAL BUILDING • 1,064 SF
    Value Estimation by Request
    40 Park Dr, East Palestine, OH 44413-1850
    View details
    22285 State Rte 62

    22285 State Rte 62

    MEDICAL BUILDING • 3,959 SF
    Value Estimation by Request
    22285 State Rte 62, Alliance, OH 44601-9104
    View details
    200 Pershing St

    200 Pershing St

    MEDICAL BUILDING • 5,380 SF
    Value Estimation by Request
    200 Pershing St, Salem, OH 44460-3047
    View details
    356 Lincoln Way

    356 Lincoln Way

    MEDICAL BUILDING • 4,605 SF
    Value Estimation by Request
    356 Lincoln Way, Lisbon, OH 44432-1443
    View details
    State St

    State St

    MEDICAL BUILDING • 4,266 SF
    Value Estimation by Request
    State St, Salem, OH 44460
    View details
    16218 Saint Clair Ave

    16218 Saint Clair Ave

    MEDICAL BUILDING • 4,540 SF
    Value Estimation by Request
    16218 Saint Clair Ave, East Liverpool, OH 43920-9449
    View details
    16351 State Rte 267

    16351 State Rte 267

    MEDICAL BUILDING • 2,880 SF
    Value Estimation by Request
    16351 State Rte 267, East Liverpool, OH 43920-3974
    View details

    Columbiana County, OH Medical Office Space Investment Opportunities Market Analysis

    Explore 111 medical office space for sale in Columbiana County, OH on our real estate platform. These investment opportunities span a total of 2,314,806 square feet of properties for sale, with an estimated market value of $26,070,000.

    Sale prices for medical spaces in Columbiana County, OH start at $50,000, averaging $292,921, and reaching up to $3,295,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    List
    Map

    Medical Office Space by market

    Browse Medical Office Space for Sale Near Columbiana, OH

    Popular Categories

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!