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San Patricio County, TX Medical Office Space for Lease

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Portland, TX Commercial Lease Unit
$2,600 / Mo
1,755 SF

Portland, TX Commercial Lease Unit

607 Railroad Dr, Portland, TX 78374

Versatile 1755 SF commercial space in Portland's LED District.

  • Prime location in the heart of the LED (Leisure & Entertainment District), near the new City's 5th & Elm facility.
  • Versatile mixed layout with over 1750 SF, suitable for various business types.
  • Includes both a half‑restroom and a full‑restroom with a shower.
  • Features 2 closed‑door offices, 3 larger open spaces, and a potential 3rd office space.
  • No NNN assessment, and water/sewer/trash are included in the rent.
Updated: Nov 13, 2025
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Office/Medical Space For Lease
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Office/Medical Space For Lease

209 E Cedar Dr, Portland, TX 78374

Office and medical spaces available for lease with easy access.

  • Excellent office/medical location
  • Ample Parking available for staff and clients
  • Easy access for all
  • Close to city offices
  • 1,650 SF available
Updated: Jan 3, 2024
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Retail Strip Center Space
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Retail Strip Center Space

Retail, service, medical, or office space available for rent.

2030 Us Highway 181, Portland, TX 78374
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Based on your search, we've compiled 8 Potential Opportunities for your consideration. Besides 3 Active listings in San Patricio County, TX, we suggest exploring alternatives. Similar 5 Properties for Sales.

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Consider Similar Space for Sale. We found 5 Spaces in Nearby Locations matching your search parameters.

Restaurant with Drive-Thru on Highway
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Restaurant with Drive-Thru on Highway

Commercial property with drive-thru, ideal for restaurant or retail.

400 S San Patricio St, Sinton, TX 78387
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Versatile Commercial Building in Mathis, TX
$175,000
12,930 SF

Versatile Commercial Building in Mathis, TX

13,000 sqft commercial building in downtown Mathis, Texas.

108 E San Patricio Ave, Mathis, TX 78368
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Commercial/Medical Building For Sale
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3,868 SF

Commercial/Medical Building For Sale

Commercial or medical building with utilities included and quick access.

1133 E Sinton St, Sinton, TX 78387
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Aransas Pass Commercial Property
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60,445 SF

Aransas Pass Commercial Property

Spacious property on 4 acres, ideal for medical uses.

1711 W Wheeler Ave, Aransas Pass, TX 78336
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Former Regional Medical Center Opportunity
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60,445 SF

Former Regional Medical Center Opportunity

60,445 SF medical center on 4 acres for sale.

1711 W Wheeler Ave, Aransas Pass, TX 78336
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San Patricio County, TX Medical Office Space Leasing Opportunities Market Analysis

Explore Medical Office Space leasing options in San Patricio County, TX with 3 listings featured on our commercial real estate exchange. The current inventory includes 76,447,800 square feet of properties with an estimated lease value of $17 SF/Yr.

Estimated lease rates for Medical Office Space in San Patricio County, TX begin at $17 SF/Yr, with an average of $17 SF/Yr and extend to $17 SF/Yr.
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