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Brazoria County, TX Medical Office Space for Lease

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8 results
Modern Office Space in Pearland
$22 SF/Yr
1,200 SF

Modern Office Space in Pearland

2743 Smith Ranch Road, Pearland, TX

Upscale office space near highways, shopping, and medical facilities.

  • Unmatched accessibility and visibility near major highways, Pearland Town Center, dining, shopping, and top‑rated medical facilities.
  • Move‑in ready units, allowing for immediate occupancy.
  • Premium finishes, including upgraded flooring.
  • Suitable for medical practices, law firms, real estate offices, and financial services.
  • Opportunity to combine multiple units to create a custom layout.
Updated: Nov 23, 2025
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Pearland Retail/Office/Medical Space For Lease
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Pearland Retail/Office/Medical Space For Lease

2336 North Texas Avenue, Pearland, TX 77581

High-visibility location suitable for retail, office, or medical businesses.

  • High‑visibility location on North Texas Avenue with strong daily traffic counts.
  • Flexible floor plan suitable for retail, office, medical, or service‑based businesses.
  • Convenient access to SH 288 and Broadway (FM 518).
  • Ample on‑site parking for customers and staff.
  • Close proximity to Pearland Town Center, major retailers, dining, and growing residential developments.
Updated: Dec 18, 2025
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Pearland Medical Office Sublease
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2,543 SF

Pearland Medical Office Sublease

Turnkey pediatric clinic sublease in Pearland's medical corridor.

1416 East Broadway Street, Pearland, TX 77581
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Move-In-Ready Emergency Room Center
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13,600 SF

Move-In-Ready Emergency Room Center

Emergency Room Center with 7 exam rooms and ample parking.

11713 Shadow Creek Parkway, Pearland, TX
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Prime Commercial Land For Lease
$0.36 SF/Yr

Prime Commercial Land For Lease

1.432-acre commercial lot in Alvin's growing corridor for lease.

9630 FM 1462, Alvin, TX 77511
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Medical CoWorking Space in Pearland
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Medical CoWorking Space in Pearland

Furnished medical space for rent in Pearland, Texas.

3129 Kingsley Dr, Suite 1940, Pearland, TX 77584
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Pearland Medical/Retail Space Available
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5,000 SF

Pearland Medical/Retail Space Available

5,000 SF medical/retail space in Pearland, Texas.

11555 Magnolia Pkwy, Pearland, TX 77584
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Medical Space in Pearland
$26 SF/Yr
1,949 SF

Medical Space in Pearland

Second generation medical space in a rapidly expanding area.

12000-12006 Shadow Creek Parkway, Pearland, TX
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Based on your search, we've compiled 19 Potential Opportunities for your consideration. Besides 8 Active listings in Brazoria County, TX, we suggest exploring alternatives. Similar 7 Properties for Sales.

Explore Similar Spaces for Sale in Brazoria County, TX

Consider Similar Space for Sale. We found 7 Spaces matching your search parameters.

Move-in Ready Medical Office Suite
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1,954 SF

Move-in Ready Medical Office Suite

Versatile medical office near CHI St. Luke's Health-Brazosport Hospital.

215 S. Oak Dr. Suite W, Lake Jackson, TX 77566
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Medical Office Near Hospital
Contact for pricing
1,493 SF

Medical Office Near Hospital

Professional medical office space near CHI St. Luke's Hospital.

215 S Oak Dr., Suite K, Lake Jackson, TX 77566
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Manvel Commercial Building For Sale
$550,000
3,584 SF

Manvel Commercial Building For Sale

Commercial building in rapidly growing area with multiple opportunities.

7318 Rodgers Rd, Manvel, TX 77578
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Lake Jackson Medical Office Building
$900,000
2,779 SF

Lake Jackson Medical Office Building

Medical office building with operating room in Lake Jackson, TX.

215 Oak Dr S, Lake Jackson, TX 77566
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Pearland Office Condo For Sale
$399,000
1,225 SF

Pearland Office Condo For Sale

1,225 SF office condo ideal for professional or medical use.

3129 Kingsley Dr, Pearland, TX 77584
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Pearland Tranquility Center Investment Opportunity
$9,995,000
39,065 SF

Pearland Tranquility Center Investment Opportunity

Four buildings with diverse tenants and income potential in Pearland.

7918 Broadway St, Pearland, TX 77581
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Versatile Commercial Property in Alvin
$399,000
1.00 Acre

Versatile Commercial Property in Alvin

Commercial property suitable for office, medical, or spa use.

3373 E Highway 6, Alvin, TX 77511
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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Highway 72 Corner Lot
$6,500 /Mo
1,875 SF

Highway 72 Corner Lot

1.6 acre commercial lot for rent on Highway 72.

30472 Highway 72, Madison, AL 35756
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El Paso Commercial Land Lease
$3,600 /Mo

El Paso Commercial Land Lease

Commercial land for lease in a strategic El Paso location.

5538 E Paisano Drive, El Paso, TX 79905
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Prime Commercial Lot For Rent
$7,500 /Mo

Prime Commercial Lot For Rent

0.66 acre commercial lot with high visibility.

Tift Avenue N, Tifton, GA 31794
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Valdosta Commercial Land For Lease
Contact for pricing
43,560 SF

Valdosta Commercial Land For Lease

Prime commercial land in high-growth Valdosta corridor, suitable for various uses.

0 Inner Perimeter Rd & Park Ave., Valdosta, GA 31602
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Brazoria County, TX Medical Office Space Leasing Opportunities Market Analysis

Explore Medical Office Space leasing options in Brazoria County, TX with 8 listings featured on our commercial real estate exchange. The current inventory includes 196,020,000 square feet of properties with an estimated lease value of $32 SF/Yr.

Estimated lease rates for Medical Office Space in Brazoria County, TX begin at $10 SF/Yr, with an average of $16 SF/Yr and extend to $22 SF/Yr.
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