Brazoria County, TX Medical Office Space for Rent & Lease

Updated: Nov 24, 2025

Medical Space in Pearland

12000-12006 Shadow Creek Parkway, Pearland, TX

$26.50 SF/Yr

1,949 sqft

Located in rapidly‑expanding Pearland
2nd Generation Medical space available
Generous TI packages
Master‑planned class A Retail Complex and premier Business destination
Large open floorplates providing efficient and flexible space planning

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Updated: Jun 6, 2025

Modern Office Space in Pearland

2743 Smith Ranch Road, Pearland, TX

$14 SF/Yr

1,200 sqft

Unmatched accessibility and visibility near major highways, Pearland Town Center, dining, shopping, and top‑rated medical facilities.
Move‑in ready units, allowing for immediate occupancy.
Premium finishes, including upgraded flooring.
Suitable for medical practices, law firms, real estate offices, and financial services.
Opportunity to combine multiple units to create a custom layout.

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Medical Office Plaza Near Hospital

8633 West Broadway Street, Pearland, TX 77584

Contact for pricing

5,654 sqft

Well-positioned medical and general office space with three prominently visible buildings near a major Pearland hospital.

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Medical CoWorking Space in Pearland

3129 Kingsley Dr, Suite 1940, Pearland, TX 77584

$12 SF/Yr

Furnished medical space for rent in Pearland, Texas.

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Pearland Central Medical Plaza

8603 Broadway St, Pearland, TX 77584

Contact for pricing

11,557 sqft

Medical office space in high-traffic Pearland location.

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Multi-Entrance Flex Office Suites

127 Circle Way St, Lake Jackson, TX 77566

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4,350 sqft

Flexible office or medical space with three exterior entrances and an adjoining patio for multi-suite occupancy or subleasing.

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Pearland Medical Office Sublease

1416 East Broadway Street, Pearland, TX 77581

Contact for pricing

2,543 sqft

Turnkey pediatric clinic sublease in Pearland's medical corridor.

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Pearland Medical/Retail Space Available

11555 Magnolia Pkwy, Pearland, TX 77584

$24 SF/Yr

5,000 sqft

5,000 SF medical/retail space in Pearland, Texas.

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Based on your search, we've compiled 15 Potential Opportunities for your consideration. Besides 8 Active listings in Brazoria County, TX, we suggest exploring alternatives. Similar 3 Properties for Sales.

Similar Spaces for Sale in Brazoria County, TX

Consider Similar Space for Sale. We found 3 Spaces matching your search parameters.

Move-In-Ready Medical Office Suite

215 Oak Dr S, Lake Jackson, TX 77566

$825,000

3,337 sqft

Fully equipped medical office suite in a Lake Jackson medical office park with direct Highway 288 access.

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Manvel Commercial Building For Sale

7318 Rodgers Rd, Manvel, TX 77578

$550,000

3,584 sqft

Commercial building in rapidly growing area with multiple opportunities.

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Pearland Tranquility Center Investment Opportunity

7918 Broadway St, Pearland, TX 77581

$8,995,000

39,065 sqft

Four buildings with diverse tenants and income potential in Pearland.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Office Development Land For Lease

1323 Strawfloor Drive, Jonesboro, AR 72401

Contact for pricing

4,000 sqft

2.43 acres for office development with build-to-suit opportunity.

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Corner Lot on Highway 72

30472 Highway 72, Madison, AL 35756

$5,000/Mo

1,875 sqft

1.7 acre corner lot zoned for commercial, medical, residential.

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Commercial Land for Long-Term Lease

5538 E Paisano Drive, El Paso, TX 79905

$5,950/Mo

Lease a C4-zoned lot with easy interstate access, suited for a range of business and professional uses.

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Prime Commercial Lot For Rent

Tift Avenue N, Tifton, GA 31794

$7,500/Mo

0.66 acre commercial lot with high visibility.

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Brazoria County, TX Medical Office Space Market Trends and Statistics

Explore Medical Office Space leasing options in Brazoria County, TX with 8 listings featured on our commercial real estate exchange. The current inventory includes 8,149 square feet of properties with an estimated lease value of $64.50 SF/Yr.

Estimated lease rates for Medical Office Space in Brazoria County, TX begin at $14 SF/Yr, with an average of $21.50 SF/Yr and extend to $26.50 SF/Yr.