Medical Space

Okc, OK Medical Office Space for Lease

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Found 35 medical office space listings for lease in Okc, OK, averaging $19/SF/YR. Use lease type data to compare options faster.
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Renovated Office Units
Updated: Sep 24, 2025
Renovated Office Units

2812 W Hefner Road, Oklahoma City, OK 73120

$2,200/Mo
3,024 sqft 0.29 AC lot
3,024 SF office property with two units
Each side measures over 1,500 square feet
East unit renovated with new paint, flooring, and lighting
ADA‑compliant areas in the east unit
Commercial zoning on 0.287 acres
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Medical Office Suite with Conference Room
Updated: Aug 16
Medical Office Suite with Conference Room

6510 S Western Ave Unit 213, Oklahoma City, OK 73139

$3,000/Mo
2,800 sqft
Approximately 2,800 SF of medical office space
More than 10 rooms with reception area and conference room
Multiple restrooms and a breakroom
Parking for over 25 cars
Easy access to I‑240, I‑35, and I‑44
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Move-In Ready Office Suites
Move-In Ready Office Suites

1409 NW 122nd Street Unit: Suite A, Oklahoma City, OK 73114

$2,500/Mo
6–10 people  1,550 sqft  Built 2026

Two professionally designed office suites are available, each with a reception area, private offices, restrooms, and break room.

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Medical Office Building with Ample Parking
Medical Office Building with Ample Parking

937 SW 89th St, Oklahoma City, OK 73139

$16 SF/Yr
Multi-tenant  8,530 sqft  Built 1984
Highway access  C-3

Three-suite medical office building with ample parking, strong signage, and two currently vacant built-out suites.

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Multi-Office Suite with Two Entrances
Multi-Office Suite with Two Entrances

505 NE 46th Street, Oklahoma City, OK 73105

Modified gross
$1,800/Mo
13–22 people  3,420 sqft  Built 1960
3 private offices  2 meeting rooms

A flexible office layout includes private offices, conference rooms, a kitchenette, and a restroom with shower.

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New Medical Office Space
New Medical Office Space

14901 N Rockwell Ave, Oklahoma City, OK 73142

$25 SF/Yr
3,000 sqft  Built 2024

A dental practice facility is offered alongside adjoining land for build-to-suit development.

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1,300 - 6,500 SF of Retail Space Available in Oklahoma City, OK 73128
1,300 - 6,500 SF of Retail Space Available in Oklahoma City, OK 73128

1600 S Morgan Rd, Oklahoma City, OK 73128

Triple net (NNN)
$14 SF/Yr
1,300–6,500 sqft  Built 2023

Growing Neighborhood Retail Center

56 parking spaces
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Medical Office Suite
Medical Office Suite

3110 SW 89th St, Oklahoma City, OK 73159

Modified gross
Contact for pricing
7,949 sqft

The layout provides exam rooms, private offices, a waiting area, and a break room.

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Medical Office with X-Ray Room
Medical Office with X-Ray Room

4525 S. Klein Avenue, Oklahoma City, OK 73109

$3,750/Mo

The office includes clinical rooms, administrative offices, staff workspace, and a breakroom.

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Office Space Near Tinker AFB
Office Space Near Tinker AFB

3404 South Douglas Boulevard, Oklahoma City, OK 73150

$32 SF/Yr
12,000 sqft

Office space for rent near I-40 and Douglas Blvd.

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New Office Units with Healthcare Plumbing
New Office Units with Healthcare Plumbing

14413 N. MacArthur Boulevard, Oklahoma City, OK 73142

$26 SF/Yr
1 space  Built 2026
Highway access + Road access

Custom-built space supports general office and healthcare users.

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Secured-Entry Office and Medical Space
Secured-Entry Office and Medical Space

6300 NW Expressway, Oklahoma City, OK 73132

Full service
Contact for pricing
13–22 people  1 space  3,393 sqft
Highway access + Road access

Tastefully updated office or medical suite with secured entry and frontage facing NW Expressway.

Secured Entry
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Medical Office Space
Medical Office Space

1224 SW 104th St, Oklahoma City, OK 73139

$21 SF/Yr
Built 2009
Highway access

The property offers access to I-35 and I-44 from southwest Oklahoma City.

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Medical Office Suite with X-Ray
Medical Office Suite with X-Ray

810 SW 89th Street, Oklahoma City, OK 73139

$16 SF/Yr
27,124 VPD

Former medical suite available with an X-ray room and treatment offices in a retail shopping center environment.

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Open-Plan Retail Office Sublease
Open-Plan Retail Office Sublease

101 NE 82nd St, Oklahoma City, OK 73114

$23 SF/Yr
1 space  Built 2024

Sublease space delivered as open plan in an up-and-coming mixed-use development at 101 NE 82nd.

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Retail Space with Shell Interior
Retail Space with Shell Interior

4 Southeast 59th Street, Oklahoma City, OK 73149

$16 SF/Yr
Built 2026

The unfinished interior allows a tenant to plan a layout around its operational needs.

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Medical Office Space with Clear Span
Medical Office Space with Clear Span

12312 Market Dr, Oklahoma City, OK 73114

Triple net (NNN)
Contact for pricing
2,702 sqft  clear-span
Highway access

New construction medical/professional office space with clear-span design and flexible floor planning.

Visibility and signage
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Medical Office Space
Medical Office Space

8516 S Portland Ave, Oklahoma City, OK 73159

Triple net (NNN)
Contact for pricing
5,971 sqft

Newly built clinical suites offer a ready-to-occupy setting with on-site parking.

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Medical Office Space with Frontage Signage
Medical Office Space with Frontage Signage

8811 E Reno Ave, Oklahoma City, OK 73110

Modified gross
Contact for pricing
2,456 sqft
Highway access

Medical office space with available frontage signage, maintained landscaping, and ample parking in Oklahoma City.

Frontage signage  Manicured landscaping  Ample parking
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Multi-Floor Medical Office Space
Multi-Floor Medical Office Space

3110 SW 89th, Oklahoma City, OK 73159

$28 SF/Yr
Built 2008
Highway access

Move-in-ready medical space with multiple floor plan options and ample parking.

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Medical Office Space with Exam Rooms
Medical Office Space with Exam Rooms

12516 N May Ave, Oklahoma City, OK 73120

$17.50 SF/Yr
Built 1980 / renov 2000
Highway access  C-3

C-3 zoning permits retail, office, and service uses.

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Strip Mall With Medical Suite
Strip Mall With Medical Suite

1317 Southeast 44th Street, Oklahoma City, OK 73129

$14 SF/Yr
Highway access

Retail center near a highway exit includes a completed medical suite and additional spaces for retail and service users.

On-site gas station
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Medical Office Space
Medical Office Space

5611 MOSTELLER DR, Oklahoma City, OK 73112

Contact for pricing
3,405 sqft

Medical office space is available for lease within a commercial property built in 1974.

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Medical Office Space Available
Medical Office Space Available

4215 N. Classen Boulevard, Oklahoma City, OK 73118

$14 SF/Yr
Built 1977

Medical office space with exam rooms and reception area.

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Okc, OK Medical Office Space Lease Rates & Market Statistics

Explore 35 Medical Office Space listings for lease in Okc, OK on Realmo, a commercial real estate exchange covering the Okc area. The current inventory totals 110,023 square feet of properties — an average of ~3,150 SF per listing.

Medical Office Space lease rates in Okc range from $8.73 SF/Yr at the entry level to $32 SF/Yr at the top of the market, averaging $18.96 SF/Yr. That's a 4x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. The local average of $18.96 SF/Yr is in line with the Oklahoma state average.

Medical Office Space listings make up 13% of the 268 Office Spaces currently for lease in Okc, with asking rates averaging $18.96 SF/Yr — 12% above the citywide Office Spaces average of $16.89 SF/Yr. Tenants comparing options may also consider Office Units (173 listings) and Office buildings (66 listings) elsewhere in the Okc market.

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