New Mexico
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Space Uses
    1
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    • Hospitality
    • Sports & Entertainment
    • Specialty
    Rent
    Rent
    $
    $
    Size
    Property Size / SF

    Santa Fe County, NM Medical Office Space for Lease

    Notify Me
    List
    Map
    Albuquerque, NM Las Cruces, NM Santa Fe, NM
    16 results
    Class A Office Suite
    $25 SF/Yr
    2,998 SF

    Class A Office Suite

    2945 E Rodeo Park, Santa Fe, NM 87505

    Furnished office suite with high-quality finishes and excellent accessibility.

    • Turnkey, fully furnished Class A office suite with high‑quality finishes.
    • Convenient location near I‑25 and Rail Runner with dedicated street‑level parking.
    • Includes reception/waiting area, private offices, conference rooms, and break room.
    • Abundant natural light from numerous windows.
    • Secure and professional entrance.
    Updated: Apr 21
    View details
    Professional Office Suites For Lease
    $15 SF/Yr
    3,087 SF

    Professional Office Suites For Lease

    2006 Botulph, Santa Fe, NM 87505

    Premium office suites in Santa Fe's medical and business corridor.

    • Prime location in Santa Fe's medical and business corridor
    • Flexible suite configurations and 11,323+\/- RSF of vacancy, ideal for owner‑users, investors, or full‑building HQ
    • Excellent natural light and ADA‑accessible restrooms
    • Elevator access to second‑floor office suites with views
    • Freshly updated with a new asphalt overlay and restriped 54‑space parking lot
    Updated: Dec 10, 2025
    View details
    Santa Fe Office Space Available
    $15 SF/Yr
    9,504 SF

    Santa Fe Office Space Available

    Premium ground floor office with basement storage in Santa Fe.

    2006 Botulph, Santa Fe, NM 87505
    View details
    Santa Fe Commercial Condo
    $1,710/Mo
    795 SF

    Santa Fe Commercial Condo

    Commercial condo for lease, ideal for medical use.

    2213 Brothers Road, Santa Fe, NM 87505
    View details
    Renovated Office Space in Santa Fe
    $2,808/Mo
    1,774 SF

    Renovated Office Space in Santa Fe

    Newly renovated office space with nine private offices for lease.

    2019 Galisteo Street, Santa Fe, NM 87505
    View details
    Santa Fe Commercial Condo
    $1,710/Mo
    795 SF

    Santa Fe Commercial Condo

    Commercial condo for lease, ideal for medical use.

    2213 Brothers Road, Santa Fe, NM 87505
    View details
    Santa Fe Commercial Space Available
    $3,300/Mo
    2,000 SF

    Santa Fe Commercial Space Available

    Prime commercial space for lease in Santa Fe's Rodeo District.

    3600 Rodeo, Santa Fe, NM 87507
    View details
    Move-in Ready Office Suite
    $2,090/Mo
    1,254 SF

    Move-in Ready Office Suite

    Professional office space with private entrance, convenient location, parking.

    2945 Rodeo Park E, Santa Fe, NM 87505
    View details
    Santa Fe Ground-Floor Office Space
    $3,350/Mo
    1,600 SF

    Santa Fe Ground-Floor Office Space

    Well-located ground-floor office space with easy access to major thoroughfares.

    404 Kiva Court, Santa Fe, NM 87505
    View details
    Santa Fe Commercial Building For Lease
    $3,500/Mo
    2,153 SF

    Santa Fe Commercial Building For Lease

    Well-maintained commercial building suitable for medical or office use.

    1313 S. St. Francis Drive, Santa Fe, NM 87505
    View details
    Santa Fe Commercial Space Available
    $19 SF/Yr
    1,277 SF

    Santa Fe Commercial Space Available

    Multi-tenant property with diverse tenant mix in Santa Fe.

    1300 Luisa Street, Santa Fe, NM 87505
    View details
    Remodeled Medical Office Space Available
    $20 SF/Yr
    6,000 SF

    Remodeled Medical Office Space Available

    Premier medical office space for lease in Santa Fe, NM.

    1650 Hospital, Santa Fe, NM 87505
    View details
    Medical Office Building For Lease
    Contact for pricing
    15,398 SF

    Medical Office Building For Lease

    15,398 SF medical office with operating rooms, ample parking.

    1620 Hospital Dr, Santa Fe, NM
    View details
    Santa Fe Medical Office Space
    Contact for pricing
    3,667 SF

    Santa Fe Medical Office Space

    Medical office suites for lease near St. Vincent's Hospital.

    435 St. Michael's Drive, Santa Fe, NM
    View details
    Santa Fe Retail/Office Space
    $5,629/Mo
    3,860 SF

    Santa Fe Retail/Office Space

    High-traffic location near downtown with medical build-out and great visibility.

    510 N Guadalupe, Santa Fe, NM 87501
    View details
    Santa Fe Retail/Office Space
    $5,629/Mo
    7,371 SF

    Santa Fe Retail/Office Space

    High-traffic location near downtown with retail and office potential.

    510 N Guadalupe St Suite C1, Santa Fe, NM 87501
    View details
    Based on your search, we've compiled 32 Potential Opportunities for your consideration. Besides 16 Active listings in Santa Fe County, NM, we suggest exploring alternatives. Similar 12 Properties for Sales.

    Similar Spaces for Sale in Santa Fe County, NM

    Consider Similar Space for Sale. We found 12 Spaces matching your search parameters.

    Versatile Office Space in Santa Fe
    $450,000
    1,600 SF
    Versatile Office Space in Santa Fe

    Spacious office suites suitable for medical, administrative, or professional use.

    460 Saint Michaels Drive, Santa Fe, NM 87505

    View details
    Professional Office Building in Santa Fe
    $3,250,000
    20,467 SF
    Professional Office Building in Santa Fe

    Two-story office building near medical hub with flexible configurations.

    2006 Botulph Road, Santa Fe, NM 87505

    View details
    Professional Office Condo For Sale
    $565,000
    1,384 SF
    Professional Office Condo For Sale

    Professional office condo in high-traffic Santa Fe location.

    103 S St Francis Drive, Santa Fe, NM 87501

    View details
    Renovated Commercial Property with Courtyard
    $695,000
    2,107 SF
    Renovated Commercial Property with Courtyard

    Sustainable commercial property ideal for office or medical use.

    1315 S St Francis Drive, Santa Fe, NM 87505

    View details
    Santa Fe Professional Office Building
    $1,700,000
    9,592 SF
    Santa Fe Professional Office Building

    Two-story office and research facility in central Santa Fe.

    124 Siringo Rd, Santa Fe, NM 87505

    View details
    Santa Fe Professional Office Building
    $3,250,000
    20,467 SF
    Santa Fe Professional Office Building

    Two-story office building in Santa Fe's medical and business corridor.

    2006 Botulph, Santa Fe, NM 87505

    View details
    Santa Fe Redevelopment Opportunity
    $10,000,000
    30,760 SF
    Santa Fe Redevelopment Opportunity

    2.9-acre parcel near Railyard with redevelopment potential.

    1625 Paseo de Peralta, Santa Fe, NM 87501

    View details
    Remodeled Medical Office Building
    $2,100,000
    7,820 SF
    Remodeled Medical Office Building

    Newly remodeled medical office building with daycare center.

    450 St Michaels Dr, Santa Fe, NM 87505

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    El Paso Commercial Land Lease
    $3,600/Mo

    El Paso Commercial Land Lease

    Commercial land for lease in a strategic El Paso location.

    5538 E Paisano Drive, El Paso, TX 79905
    View details
    Grand Junction Commercial Land Lease
    $9,656/Mo

    Grand Junction Commercial Land Lease

    0.74 acre commercial land for lease in Grand Junction.

    Highway 6&50, Grand Junction, CO 81505
    View details
    Grand Junction Commercial Land Opportunity
    $17,728/Mo

    Grand Junction Commercial Land Opportunity

    1.36 acre commercial land for lease in Grand Junction.

    Sanford Drive, Grand Junction, CO 81505
    View details
    Office Development Land For Lease
    Contact for pricing
    4,000 SF

    Office Development Land For Lease

    2.43 acres for office development with build-to-suit opportunity.

    1323 Strawfloor Drive, Jonesboro, AR 72401
    View details

    Santa Fe County, NM Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Santa Fe County, NM with 16 listings featured on our commercial real estate exchange. The current inventory includes 44,468 square feet of properties with an estimated lease value of $275 SF/Yr.

    Estimated lease rates for Medical Office Space in Santa Fe County, NM begin at $9 SF/Yr, with an average of $19 SF/Yr and extend to $25 SF/Yr.
    List
    Map