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    Wilmington, NC Medical Office Space for Lease

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    Leland, NC Navassa, NC Belville, NC
    8 results
    Move-in Ready End-Unit in Wilmington
    $3,250/Mo
    1,861 SF

    Move-in Ready End-Unit in Wilmington

    3910 Princess Place Drive, Wilmington, NC 28405

    Versatile commercial space suitable for daycare, healthcare, or office use.

    • Rare end‑unit with O&I zoning suitable for various uses (childcare, healthcare, office).
    • Move‑in ready build‑out, previously a licensed daycare, with flexible rooms and private office.
    • Generous fenced side yard offering outdoor programming or secure play space.
    • End‑unit positioning provides abundant natural light, privacy, and street presence.
    • Thoughtfully configured layout with large lobby, oversized rooms, and a dedicated private office with kitchen.
    Updated: Jan 15
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    Wilmington Commercial Space For Lease
    $16,500/Mo
    10,000 SF

    Wilmington Commercial Space For Lease

    2451 College Road, Wilmington, NC 28412

    Two-story building in the heart of Wilmington available for lease.

    • High‑traffic location on S College Rd (36,000+ cars/daily).
    • Regional Business (RB) zoning allows for a multitude of uses.
    • Over 10,000 square feet on two levels, ideal for multi‑tenant suites.
    • 50 parking spaces with rear fenced and gated parking area.
    • Current configuration includes 22 offices and 5 conference rooms.
    Updated: Oct 18, 2025
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    Medical Office Space Available
    $28 SF/Yr
    4,464 SF

    Medical Office Space Available

    Class A medical office space for lease or sale.

    6740 Rock Spring Rd, Wilmington, NC
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    Medical Office Space in Mayfaire
    $32 SF/Yr
    9,517 SF

    Medical Office Space in Mayfaire

    Premier medical office space available for sublease in Wilmington.

    6781 Parker Farm Dr, Wilmington, NC
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    Wilmington Medical Office For Sale
    Contact for pricing
    66,164 SF

    Wilmington Medical Office For Sale

    Medical office building in Wilmington's established medical district.

    1202 Medical Center Dr, Wilmington, NC
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    Medical Space Near Hospital
    Contact for pricing
    2,522 SF

    Medical Space Near Hospital

    2,522 SF medical space in Hospital Plaza Office Park.

    1902-1906 Meeting Ct, Wilmington, NC
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    Medical Office Building For Sale
    Contact for pricing
    4,886 SF

    Medical Office Building For Sale

    4,886 SF medical office building on 1.36 acres.

    5245 South College, Wilmington, NC
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    Office/Medical Space Near Hospital
    $14 SF/Yr
    10,960 SF

    Office/Medical Space Near Hospital

    Office and medical space with excellent visibility and access.

    2222 S 17th St, Wilmington, NC
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    Based on your search, we've compiled 20 Potential Opportunities for your consideration. Besides 8 Active listings in Wilmington, NC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 4 Properties for Sales.

    Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Medical Office Space Near Hospital
    $4,750/Mo
    4,200 SF

    Medical Office Space Near Hospital

    Move-in ready medical office space near Onslow Memorial Hospital.

    219 Station Street, Jacksonville, NC 28546
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    Leland Medical Office Opportunity
    $3,000/Mo
    1,555 SF

    Leland Medical Office Opportunity

    Move-in ready medical suite in a growing community.

    509 Olde Waterford Way, Leland, NC 28451
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    Medical Office Condo in Leland
    $2,000/Mo
    1,293 SF

    Medical Office Condo in Leland

    Medical office condo suite in Olde Waterford, Leland, NC.

    Olde Waterford Way 509, Leland, NC
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    Medical Office Space Available
    $6,510/Mo
    5,097 SF

    Medical Office Space Available

    5097 SF medical office space in Walgreens Plaza.

    3069 Richlands Highway, Jacksonville, NC 28540
    View details

    Similar Spaces for Sale in Wilmington, NC

    Consider Similar Space for Sale. We found 4 Spaces matching your search parameters.

    Versatile Commercial Property Near Medical Clinic
    $700,000
    3,598 SF
    Versatile Commercial Property Near Medical Clinic

    Community business zoned property with commercial kitchen and outdoor space.

    3101 Princess Place Drive, Wilmington, NC 28405

    View details
    Wilmington Office Building For Sale
    $1,250,000
    3,832 SF
    Wilmington Office Building For Sale

    Professional office space in central Wilmington with ample parking.

    34 Covil Avenue, Wilmington, NC

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    Turnkey Medical Office For Sale
    $2,680,000
    7,445 SF
    Turnkey Medical Office For Sale

    Move-in-ready medical facility in a prime location.

    1222 Medical Center Drive, Wilmington, NC

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    Move-in Ready Medical Office Building
    $7,200,000
    23,082 SF
    Move-in Ready Medical Office Building

    Immaculate medical office building near Novant Health New Hanover Hospital.

    1729 New Hanover Medical Park Dr, Wilmington, NC

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Commercial Lot For Rent
    $7,500/Mo

    Prime Commercial Lot For Rent

    0.66 acre commercial lot with high visibility.

    Tift Avenue N, Tifton, GA 31794
    View details
    Valdosta Commercial Land For Lease
    Contact for pricing
    43,560 SF

    Valdosta Commercial Land For Lease

    Prime commercial land in high-growth Valdosta corridor, suitable for various uses.

    Inner Perimeter Rd & Park Ave., Valdosta, GA 31602
    View details
    WINTER PARK Land Lease Opportunity
    $8,500/Mo
    23,056 SF

    WINTER PARK Land Lease Opportunity

    Commercial land lease opportunity in Winter Park, Florida.

    5589 LAKE HOWELL ROAD, Winter Park, FL 32792
    View details
    Corner Lot on Highway 72
    $5,000/Mo
    1,875 SF

    Corner Lot on Highway 72

    1.7 acre corner lot zoned for commercial, medical, residential.

    30472 Highway 72, Madison, AL 35756
    View details

    Wilmington, NC Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Wilmington, NC with 8 listings featured on our commercial real estate exchange. The current inventory includes 36,802 square feet of properties with an estimated lease value of $114 SF/Yr.

    Estimated lease rates for Medical Office Space in Wilmington, NC begin at $14 SF/Yr, with an average of $22 SF/Yr and extend to $32 SF/Yr.
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    Most Searched ZIP Codes in Wilmington, NC

    • 28405
    • 28412

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