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Wilmington, NC Medical Office Space for Lease

7 results
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Wilmington Commercial Space For Lease
$16,500 /Mo
10,000 SF

Wilmington Commercial Space For Lease

2451 College Road, Wilmington, NC 28412

Two-story building in the heart of Wilmington available for lease.

  • High‑traffic location on S College Rd (36,000+ cars/daily).
  • Regional Business (RB) zoning allows for a multitude of uses.
  • Over 10,000 square feet on two levels, ideal for multi‑tenant suites.
  • 50 parking spaces with rear fenced and gated parking area.
  • Current configuration includes 22 offices and 5 conference rooms.
Updated: Oct 18, 2025
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Medical Office Space Available
$28 SF/Yr
4,464 SF

Medical Office Space Available

6740 Rock Spring Rd, Wilmington, NC

Class A medical office space for lease or sale.

  • Turnkey Class A medical office space with existing upfit.
  • Upfit includes reception/waiting area with retail space, 7 exam rooms, and 3 private offices.
  • Significant cost savings compared to new construction (upfit estimated at over $500,000).
  • Option to purchase the property as a vacant unit.
  • Flexible lease options available, including potential leaseback by current owner.
Updated: Oct 15, 2025
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Medical Office Space in Mayfaire
$32 SF/Yr
9,517 SF

Medical Office Space in Mayfaire

Premier medical office space available for sublease in Wilmington.

6781 Parker Farm Dr, Wilmington, NC
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Wilmington Medical Office For Sale
Contact for pricing
66,164 SF

Wilmington Medical Office For Sale

Medical office building in Wilmington's established medical district.

1202 Medical Center Dr, Wilmington, NC
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Medical Space Near Hospital
Contact for pricing
2,522 SF

Medical Space Near Hospital

2,522 SF medical space in Hospital Plaza Office Park.

1902-1906 Meeting Ct, Wilmington, NC
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Medical Office Building For Sale
Contact for pricing
4,886 SF

Medical Office Building For Sale

4,886 SF medical office building on 1.36 acres.

5245 South College, Wilmington, NC
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Office/Medical Space Near Hospital
$14 SF/Yr
10,960 SF

Office/Medical Space Near Hospital

Office and medical space with excellent visibility and access.

2222 S 17th St, Wilmington, NC
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Based on your search, we've compiled 19 Potential Opportunities for your consideration. Besides 7 Active listings in Wilmington, NC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 4 Properties for Sales.

Explore Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Medical Office Space Near Hospital
$4,750 /Mo
4,200 SF

Medical Office Space Near Hospital

Move-in ready medical office space near Onslow Memorial Hospital.

219 Station Street, Jacksonville, NC 28546
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Leland Medical Office Opportunity
$3,000 /Mo
1,555 SF

Leland Medical Office Opportunity

Move-in ready medical suite in a growing community.

509 Olde Waterford Way, Leland, NC 28451
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Medical Office Space Available
$6,510 /Mo
5,097 SF

Medical Office Space Available

5097 SF medical office space in Walgreens Plaza.

3069 Richlands Highway unit: 5, Jacksonville, NC 28540
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Medical Office Condo in Leland
$2,000 /Mo
1,293 SF

Medical Office Condo in Leland

Medical office condo suite in Olde Waterford, Leland, NC.

Olde Waterford Way 509, Leland, NC
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Explore Similar Spaces for Sale in Wilmington, NC

Consider Similar Space for Sale. We found 4 Spaces matching your search parameters.

Versatile Commercial Property Near Medical Clinic
$700,000
3,598 SF

Versatile Commercial Property Near Medical Clinic

Community business zoned property with commercial kitchen and outdoor space.

3101 Princess Place Drive, Wilmington, NC 28405
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Wilmington Office Building For Sale
$1,250,000
3,832 SF

Wilmington Office Building For Sale

Professional office space in central Wilmington with ample parking.

34 Covil Avenue, Wilmington, NC
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Turnkey Medical Office For Sale
$2,680,000
7,445 SF

Turnkey Medical Office For Sale

Move-in-ready medical facility in a prime location.

1222 Medical Center Drive, Wilmington, NC
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Move-in Ready Medical Office Building
$7,200,000
23,082 SF

Move-in Ready Medical Office Building

Immaculate medical office building near Novant Health New Hanover Hospital.

1729 New Hanover Medical Park Dr, Wilmington, NC
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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Prime Commercial Lot For Rent
$7,500 /Mo

Prime Commercial Lot For Rent

0.66 acre commercial lot with high visibility.

Tift Avenue N, Tifton, GA 31794
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Valdosta Commercial Land For Lease
Contact for pricing
43,560 SF

Valdosta Commercial Land For Lease

Prime commercial land in high-growth Valdosta corridor, suitable for various uses.

0 Inner Perimeter Rd & Park Ave., Valdosta, GA 31602
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Winter Park Mixed-Use Opportunity
$8,500 /Mo
23,056 SF

Winter Park Mixed-Use Opportunity

Double commercial lot in Winter Park, FL, for lease.

5589 LAKE HOWELL ROAD, Winter Park, FL 32792
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Prime Land in Upper St Clair
$50,000

Prime Land in Upper St Clair

Commercial land for lease in Upper St Clair, PA.

2585 Maple Lane, Upper St Clair, PA 15241
View details

Wilmington, NC Medical Office Space Leasing Opportunities Market Analysis

Explore Medical Office Space leasing options in Wilmington, NC with 7 listings featured on our commercial real estate exchange. The current inventory includes 1,477,337,400 square feet of properties with an estimated lease value of $61 SF/Yr.

Estimated lease rates for Medical Office Space in Wilmington, NC begin at $14 SF/Yr, with an average of $20 SF/Yr and extend to $28 SF/Yr.
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