South Lyon, MI Medical Office Space for Rent & Lease

Updated: Jun 3

Retail-Office Suite in Mixed-Use Center

25660 Pontiac Trail, South Lyon, MI 48178

$22 SF/Yr

1,600 sqft · $2,933/Mo

1,600 SF retail/office suite available for lease in Gateway Commons Retail Center in South Lyon, MI
Former dental office space within a 50,000 SF mixed‑use development
Located across from South Lyon High School
Available for occupancy starting August 1, 2026

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Updated: Jun 2

Brand-New Office Medical Retail Development

26800 Pontiac Trail, South Lyon, MI 48178

$27 SF/Yr

14,200 sqft · $31,950/Mo

Brand new 14,200 SF two‑building office/medical/retail development on Pontiac Trail in South Lyon
Office/medical‑ready development slated for Summer 2026 delivery
Two‑building layout designed to support office, medical, and retail use

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South Lyon Medical Suite Opportunity

21800 Pontiac Trl, South Lyon, MI

$24 SF/Yr

1,930 sqft · $3,860/Mo

1,930 SF medical suite available for lease.

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Based on your search, we've compiled 11 Potential Opportunities for your consideration. Besides 3 Active listings in South Lyon, MI, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Medical Office Space For Lease

26750 Providence Parkway, Novi, MI 48374

$25 SF/Yr

50,028 sqft · $104,225/Mo

Medical office suites available for lease on hospital campus.

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Medical Office Suites For Lease

10020 E Professional Center Drive, Hamburg, MI 48139

$15 SF/Yr

18,000 sqft · $22,500/Mo

Medical/Office suites available in Hamburg, MI with ample parking.

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Medical/Office Suite For Lease

10020 Professional Ctr Dr, Hamburg, MI

$17 SF/Yr

4,268 sqft · $6,046/Mo

Office suite available for lease with ample parking.

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Medical Office Space For Lease

26750 Providence Pkwy, Novi, MI 48374

$25 SF/Yr

Medical office space available for lease.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Kingery Highway Commercial Development Opportunity

8501 & 8511 Kingery Highway, Willowbrook, IL 60527

$85,000 SF/Yr

High-visibility land for retail, car wash, or medical development.

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Commercial Land Parcel with Utilities

2585 Maple Lane, Pittsburgh, PA 15241

$50,000 SF/Yr

Level, fully serviced commercial parcel with approvals in place and signage permitted up to 20 sq ft.

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Beaumont Centre Outparcel Opportunity

3199 Beaumont Centre Circle, Lexington, KY 40513

Contact for pricing

Outparcel opportunity in established shopping center for ground lease.

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Prime Lexington Outlot Opportunity

3330 Partner Place, Lexington, KY 40503

Contact for pricing

Outlot for ground lease or build-to-suit in South Lexington.

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South Lyon, MI Medical Office Space Market Trends and Statistics

Explore Medical Office Space leasing options in South Lyon, MI with 3 listings featured on our commercial real estate exchange. The current inventory includes 17,730 square feet of properties with an estimated lease value of $73 SF/Yr.

Estimated lease rates for Medical Office Space in South Lyon, MI begin at $22 SF/Yr, with an average of $24 SF/Yr and extend to $27 SF/Yr.