Medical Space

South Lyon, MI Medical Office Space for Lease

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Brand-New Office Medical Retail Development
Updated: Jun 2
Brand-New Office Medical Retail Development

26800 Pontiac Trail, South Lyon, MI 48178

$27 SF/Yr
14,200 sqft
Brand new 14,200 SF two‑building office/medical/retail development on Pontiac Trail in South Lyon
Office/medical‑ready development slated for Summer 2026 delivery
Two‑building layout designed to support office, medical, and retail use
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First-Floor Medical Office Suite
Updated: Mar 3
First-Floor Medical Office Suite

12660 10 Mile Rd, South Lyon, MI 48178

$18 SF/Yr
1,100 sqft
1,100 SF first‑floor former pharmacy suite
Newer‑construction building with high‑end finishes
Road‑front signage along 10 Mile Rd
Abundant parking at the rear of the building
Village MD and Legend Health identified as building tenants
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Medical Office Suite with Signage
Medical Office Suite with Signage

21800 Pontiac Trail, South Lyon, MI 48178

$24 SF/Yr
1,930 sqft

Suite 300 offers a professional patient-facing layout with exam rooms, work areas, storage, and two restrooms.

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Two-Story Medical Office Building
Two-Story Medical Office Building

26012 Pontiac Trail, South Lyon, MI 48178

$18 SF/Yr

Two-story medical and general office building offering private-entrance suites with immediate occupancy.

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Based on your search, we've compiled 8 Potential Opportunities for your consideration. Besides 4 Active listings in South Lyon, MI, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Medical Office and Therapy Facility
Medical Office and Therapy Facility

7100 Whitmore Lake Rd, Brighton, MI 48116

Contact for pricing
70,000 sqft

For lease full medical suite with dedicated physical therapy section, security system, and celiac-safe commercial kitchen.

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Class A Campus Medical Office Building
Class A Campus Medical Office Building

26850 Providence Pkwy, Novi, MI 48374

Contact for pricing
2,950 sqft

Five-story medical office building built in 2007 with an enclosed walkway to Henry Ford Providence Novi Hospital.

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Office Unit with Exam Rooms
Office Unit with Exam Rooms

5889 Whitmore Lake Rd, Brighton, MI 48116

$14 SF/Yr
4,161 sqft

Configured professional suite with a reception area, private rooms, and an in-suite restroom.

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Medical Office Space with Enclosed Walkway
Medical Office Space with Enclosed Walkway

26850 Providence Pkwy, Novi, MI 48374

Contact for pricing
1,577 sqft

Medical office space in a five-story building with handicap accessibility and an enclosed connection to Henry Ford Providence Novi Hospital.

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South Lyon, MI Medical Office Space Lease Rates & Market Statistics

Explore 4 Medical Office Space listings for lease in South Lyon, MI on Realmo, a commercial real estate exchange covering the South Lyon area. The current inventory totals 17,230 square feet of properties.

Medical Office Space lease rates in South Lyon range from $18 SF/Yr at the entry level to $27 SF/Yr at the top of the market, averaging $21.75 SF/Yr. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. The local average of $21.75 SF/Yr is 24% above the Michigan state average of $17.47 SF/Yr.

South Lyon accounts for 3% of the 149 medical office space listings currently available across Oakland County, where nearby markets include Southfield and Farmington Hills. Medical Office Space is one of the more limited space types in South Lyon, with just 4 listings currently available — a scarcity worth factoring into lease negotiations. Also worth a look for tenants weighing alternatives: Office Units (6 listings) elsewhere in the South Lyon market.

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