Eastpointe, MI Medical Office Space for Rent & Lease

$3,500/Mo

3,631 SF

Renovated Retail Building on Gratiot

21103 Gratiot Avenue, Eastpointe, MI 48021

Turnkey retail building with modern interior on Gratiot Avenue.

Completely renovated in 2025 with new roof, electrical, and plumbing.
Turnkey asset with modern, design‑forward interior and premium finishes.
Located on highly trafficked Gratiot Avenue corridor with excellent visibility.
Approximately 3,475 square feet of modernized, ADA compliant space.
Flexible, open‑concept layout suitable for various uses (retail, office, medical, showroom).

Updated: Mar 18

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$3,500/Mo

3,475 SF

Renovated Retail Building on Gratiot

21103 Gratiot Ave, Eastpointe, MI 48021

Turnkey retail building with modern design and high-end finishes.

Completely renovated in 2025 with new roof, electrical, plumbing, and high‑end interior finishes.
Freestanding retail building on highly trafficked Gratiot Avenue.
Turnkey asset with modern, design‑forward interior and open‑concept layout.
Approximately 3,475 square feet of modernized, ADA compliant space.
Ideally suited for a wide range of uses: creative office, showroom, medical, or boutique retail.

Updated: Mar 24

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Based on your search, we've compiled 19 Potential Opportunities for your consideration. Besides 2 Active listings in Eastpointe, MI, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 9 Properties for Sales.

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

$15 SF/Yr

1,304 SF

Office Suite For Lease

Office suite with private offices, ideal for counseling-therapy use.

Saint Clair Shores, MI 48081

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$15 SF/Yr

1,500 SF

Saint Clair Shores Endcap Spaces

Endcap spaces available for medical, office, or retail use.

22030-22050 Greater Mack Ave., Saint Clair Shores, MI 48080

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2,577 SF

Renovated Medical Suite For Rent

Newly renovated medical suite with ample parking in Warren, MI.

25656 Schoenherr Rd, Warren, MI

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$17 SF/Yr

3,800 SF

Class A Medical Office Space

High visibility medical office near Ascension Macomb, quick highway access.

27450-27472 Schoenherr Rd, Warren, MI

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Similar Spaces for Sale in Eastpointe, MI

Consider Similar Space for Sale. We found 9 Spaces matching your search parameters.

$199,999

1,492 SF

Corner Retail and Office Building

Corner storefront building with dedicated parking and strong visibility for retail, office, service, or medical owner-user use.

15040 E 9 Mile Road, Eastpointe, MI 48021

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$199,000

4,197 SF

Former Medical Office Building

Former medical building for sale with an elevator-equipped finished basement and zoning that allows office, retail, and personal service uses.

20927 Kelly Road, Eastpointe, MI 48021

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Updated One-Story Retail/Office Building

$150,000

1,300 SF

Updated One-Story Retail/Office Building

Brick one-story building with large display windows, central air/heat, and flexible rooms for retail or professional use.

16906 E 9 Mile Road, Eastpointe, MI 48021

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$199,000

Former Medical Building with Parking

Eastpointe building suitable for office, retail, or personal service.

20927 Kelly Rd, Eastpointe, MI 48021

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$199,999

1,492 SF

Corner Retail and Office Building

Corner storefront with dedicated parking and strong visibility at a signalized intersection, suited for retail, office, or medical use.

15040 E 9 Mile Road, Eastpointe, MI 48021

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$499,900

5,700 SF

Move-in Ready Medical Facility

Eastpointe, MI medical facility with surgical suite for sale.

22480 Kelly Rd, Eastpointe, MI 48021

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4,125 SF

Medical Office Building Near I-94

Medical office building with exam rooms, near I-94.

18200 Ten Mile Road, Eastpointe, MI 48021

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$349,000

2,630 SF

Medical Office or Retail Space

Well-maintained office building with upgraded rooms, kitchenette, and both front and fenced parking for flexible business use.

22301 Kelly Road, Eastpointe, MI 48021

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$450,000

2,730 SF

Renovated Office with Built-in Pool

Renovated office space with top-of-the-line equipment and built-in pool.

22830 Kelly Rd, Eastpointe, MI 48021

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

$50,000 SF/Yr

Prime Land in Upper St Clair

Commercial land for lease in Upper St Clair, PA.

2585 Maple Lane, Upper St Clair, PA 15241

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$85,000 SF/Yr

Kingery Highway Commercial Development Opportunity

High-visibility land for retail, car wash, or medical development.

8501 & 8511 Kingery Highway, Willowbrook, IL 60527

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Beaumont Centre Outparcel Opportunity

Outparcel opportunity in established shopping center for ground lease.

3199 Beaumont Centre Circle, Lexington, KY 40513

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Contact for pricing

Prime Lexington Outlot Opportunity

Outlot for ground lease or build-to-suit in South Lexington.

3330 Partner Place, Lexington, KY 40503

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Eastpointe, MI Medical Office Space Market Trends and Statistics

Explore Medical Office Space leasing options in Eastpointe, MI with 2 listings featured on our commercial real estate exchange. The current inventory includes 7,106 square feet of properties with an estimated lease value of $23 SF/Yr.

Estimated lease rates for Medical Office Space in Eastpointe, MI begin at $11 SF/Yr, with an average of $11 SF/Yr and extend to $12 SF/Yr.