Medical Space

New Port Richey, FL Medical Office Space for Lease

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14 properties
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Renovated Medical Office Space
Updated: Oct 19
Renovated Medical Office Space

6102 INDIANA Avenue, New Port Richey, FL 34653

$26 SF/Yr
1,792 sqft 0.15 AC lot
1,792‑square‑foot medical office space
Renovated in 2026; offered vacant as a vanilla shell
Concrete‑block construction with stucco exterior and central HVAC
0.15‑acre lot with on‑site paved parking
Directly across from Morton Plant North Bay Hospital, a 222‑bed acute‑care facility
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Open-Plan Medical Office Space
Updated: Aug 27
Open-Plan Medical Office Space

8428 LITTLE Road, New Port Richey, FL 34654

$2,900/Mo
1,700 sqft 1.64 AC lot
Approximately 1,700 square feet of open‑plan medical office space
Separate interior entrance with dedicated access to the sublease area
Established urgent care practice occupies the larger portion of the building
Located directly on Little Road in New Port Richey, FL 34654
1.64‑acre property with public water and public sewer
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Medical Office Suite with Open Layout
Medical Office Suite with Open Layout

5341 GRAND Boulevard, New Port Richey, FL 34652

$1,570/Mo
1,350 sqft 0.03 AC lot

Open-plan medical suite includes a private office, restroom, storage, and infrastructure for medical equipment.

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Freestanding Medical Office
Freestanding Medical Office

6430 Madison St, New Port Richey, FL 34652

$4,200/Mo
3,372 sqft

Reception, private offices, treatment rooms, storage, and retained dental plumbing are part of the interior configuration.

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Built-Out Medical Office Suite
Built-Out Medical Office Suite

6333 E STATE RD 54 E, New Port Richey, FL 34653

$3,000/Mo
0.67 AC lot

Single-tenant office suite with exam rooms, reception, support areas, and on-site parking along a heavily traveled commercial corridor.

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Medical Suite in Professional Complex
Medical Suite in Professional Complex

103-5341 Grand Blvd, New Port Richey, FL 34652

$18,840/Mo
1,350 sqft

Medical suite with an open floor plan, private office, restroom, storage, and a 700-amp breaker for medical uses.

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Medical/Office Space For Rent
Medical/Office Space For Rent

5341 GRAND BOULEVARD 103, New Port Richey, FL 34652

$18,840/Mo
1,350 sqft

Medical/office space available for lease in a medical complex.

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Medical Suite with Exam Rooms
Medical Suite with Exam Rooms

8845-8849 Hawbuck St, New Port Richey, FL 34655

Contact for pricing
1,300 sqft

A private rear entrance serves a furnished medical layout with patient, clinical, and staff areas.

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Built-Out Medical Office Space
Built-Out Medical Office Space

6333-6333 State Road 54, New Port Richey, FL 34653

Contact for pricing
1,600 sqft

Move-in-ready suite with treatment rooms, reception, support areas, restrooms, and on-site parking along State Road 54.

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Medical Office Suite with Wet Rooms
Medical Office Suite with Wet Rooms

2439 Country Place Blvd, New Port Richey, FL 34655

Contact for pricing
1,563 sqft

Suite 102 offers multiple wet exam rooms and a dedicated break area within a medical office complex.

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Customizable Medical Office Suite
Customizable Medical Office Suite

8820 BELAGIO DR, New Port Richey, FL 34655

Contact for pricing
1,945 sqft

Office suite offers two entrances and an available temporary layout while the owner builds to tenant specifications.

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Medical Office Space with Shell Delivery
Medical Office Space with Shell Delivery

6102 INDIANA AVE, New Port Richey, FL 34653

Contact for pricing
0.15 AC lot

Vacant, single-story space across from a hospital, with central HVAC and paved on-site parking.

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Medical Office Space Available
Medical Office Space Available

6325 STATE ROAD 54, New Port Richey, FL

Contact for pricing
1,500 sqft 0.07 AC lot

1,500 SF medical office space for lease.

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Medical/Office Space Available
Medical/Office Space Available

9324 Florida 54, New Port Richey, FL 34655

Contact for pricing
20,000 sqft

20,000 SF medical/office space for rent.

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Based on your search, we've compiled 32 Potential Opportunities for your consideration. Besides 14 Active listings in New Port Richey, FL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 14 Properties for Sales.

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Medical Office Suite with Exam Rooms
Medical Office Suite with Exam Rooms

8849 Hawbuck Street, Trinity, FL 34655

$22.88 SF/Yr

Fitted for clinical operations, the suite includes a reception area, lab space, private office, and two restrooms.

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Bank Space With Drive-Through
Bank Space With Drive-Through

9037-9037 Us Highway 19, Port Richey, FL 34668

Contact for pricing

Former banking premises retain customer-service infrastructure, prominent signage options, and access from a major commercial corridor.

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Medical Office Space Near Hospital
Medical Office Space Near Hospital

2035 - 2055 Little Road, Trinity, FL 34655

Contact for pricing

Professionally maintained medical center with recent exterior upgrades near HCA Florida Trinity Hospital.

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Professional Office Space
Professional Office Space

8208 Washington St, Port Richey, FL 34668

Contact for pricing
5,265 sqft

Well-maintained common areas and ample parking support a 5,265-square-foot professional office space for flexible business use.

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Similar Spaces for Sale in New Port Richey, FL

Consider Similar Space for Sale. We found 14 Spaces matching your search parameters.

Remodeled Medical Office
Remodeled Medical Office

4911 STATE ROAD 54, New Port Richey, FL 34652

$1,300,000
2,784 sqft 0.65 AC lot

Updated professional layout with private rooms, work areas, cabinetry, sinks, security, and on-site parking.

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Renovated Medical Office Building
Renovated Medical Office Building

6430 Madison St, New Port Richey, FL 34652

$750,000
3,372 sqft 0.23 AC lot

The former dental practice retains plumbing infrastructure and offers a flexible mix of treatment, office, and open-plan areas.

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Remodeled Medical Office Space
Remodeled Medical Office Space

4911 STATE ROAD 54, New Port Richey, FL 34652

$1,300,000
3,064 sqft

Updated interior includes private rooms, work areas, cabinetry, counters, and multiple sinks.

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Renovated Medical Office Shell
Renovated Medical Office Shell

6102 INDIANA Avenue, New Port Richey, FL 34653

$395,000
1,792 sqft 0.15 AC lot

Vacant vanilla-shell space with central HVAC and paved on-site parking.

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Downtown Office Building
Downtown Office Building

5838 MAIN Street, New Port Richey, FL 34652

$500,000
1,900 sqft 0.08 AC lot

A single-story commercial building offers a flexible interior and three existing restrooms in a downtown setting.

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Adaptable Commercial Property on Little Road
Adaptable Commercial Property on Little Road

10129 LITTLE Rd, New Port Richey, FL 34654

$589,988
2,300 sqft 1.09 AC lot

Versatile commercial property with high visibility and accessibility.

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Medical Office with Multiroom Layout
Medical Office with Multiroom Layout

5838 MAIN ST, New Port Richey, FL 34652

$500,000
1,900 sqft

A single-story professional space has three restrooms and adjacent public parking, with additional street parking on Main Street.

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Professional Office Building Near US-19
Professional Office Building Near US-19

5438 Trouble Creek Rd, New Port Richey, FL 34652

$380,000
1,488 sqft

Professional office building in high-demand New Port Richey submarket.

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Adaptable Commercial Property on Little Road
Adaptable Commercial Property on Little Road

10129 LITTLE ROAD, New Port Richey, FL 34654

$599,988
2,337 sqft 1.09 AC lot

Versatile 2,300+ sq. ft. commercial property on over an acre.

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Mixed-Use Building with Medical Layout
Mixed-Use Building with Medical Layout

8726 OLD COUNTY ROAD 54, New Port Richey, FL 34653

$1,898,000
8,476 sqft 1.14 AC lot

C1-zoned building offers reception, exam-room flexibility, multiple restrooms, kitchens, and parking across the site.

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New Port Richey, FL Medical Office Space Lease Rates & Market Statistics

Browse 14 Medical Office Space listings for lease in New Port Richey, FL on Realmo, a commercial real estate marketplace serving the New Port Richey area. The current inventory totals 38,822 square feet of properties — an average of ~2,750 SF per listing.

Asking lease rates for Medical Office Space in New Port Richey start at $13.96 SF/Yr, average $68.39 SF/Yr, and reach $167.47 SF/Yr at the top of the market. That's a 12x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. At $68.39 SF/Yr, the local average runs 144% above Florida's state average of $28.02 SF/Yr.

New Port Richey accounts for 45% of the 31 medical office space listings currently available across Pasco County, where nearby markets include Hudson and Zephyrhills. Medical Office Space listings make up 47% of the 30 Office Spaces currently for lease in New Port Richey, with asking rates averaging $68.39 SF/Yr — 80% above the citywide Office Spaces average of $37.99 SF/Yr. Tenants comparing options may also consider Office Units (20 listings) and Office buildings (3 listings) elsewhere in the New Port Richey market.

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