Deland, FL Medical Office Space for Rent & Lease

$2,900/Mo

1,459 SF

Renovated Office Space in DeLand

125 W PLYMOUTH AVE, STE. 121 ROAD, Deland, FL 32720

Newly renovated office space suitable for medical or business use.

Newly renovated 1,459 sq ft office space suitable for medical or business use.
Centrally located near downtown DeLand, Advent Health Hospital, and Stetson University.
Features a bright reception area, large conference room, four offices, kitchen, and two bathrooms.
Includes new flooring, doors, lighting, paint, and fixtures.
On‑site property management.

Updated: Feb 13

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$25 SF/Yr

6,262 SF

Freestanding Mixed-Use Office Building

191 ENDICOTT WAY, Deland, FL 32724

Renovated freestanding building with classroom-style rooms, large windows, and new HVAC for flexible office or medical use.

6,262 (+/-) SF freestanding commercial building newly improved and renovated (block construction), built in 2011
Zoning allows multiple uses including medical office, general office, pre‑school, and restaurant (plus many more uses listed)
Lease rate reduced to $25 PSF plus NNN, with a 5‑year minimum lease term
Extremely low estimated CAM fee of $2.50 (+/-) plus property taxes and property insurance
Newly installed 3 high‑efficiency Carrier HVAC systems

Updated: May 23, 2025

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Medical/Professional Office Building For Lease

$25 SF/Yr

15,174 SF

Medical/Professional Office Building For Lease

Two-story medical/professional office building available for lease or sale.

425 S Woodland Blvd, Deland, FL 32720

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Based on your search, we've compiled 18 Potential Opportunities for your consideration. Besides 3 Active listings in Deland, FL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 7 Properties for Sales.

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Versatile Commercial Space in Orange City

$16 SF/Yr

5,774 SF

Versatile Commercial Space in Orange City

5,500 SF commercial space with flexible layout and high visibility.

346 N VOLUSIA AVENUE, Orange City, FL 32763

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$88,000 SF/Yr

5,500 SF

Versatile Commercial Space in Orange City

5,500 SF commercial space suitable for various business types.

346 N VOLUSIA Ave, Orange City, FL 32763

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Contact for pricing

2,150 SF

Sanford Office Space For Rent

2,150 SF office space near HWY 417, I-4, and 429.

245 Bellagio Circle, Sanford, FL 32771

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Contact for pricing

1,250 SF

Medical Arts Center Office Suites

Medical office suites available for lease in Sanford, Florida.

1403 Medical Plaza Dr, Sanford, FL

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Similar Spaces for Sale in Deland, FL

Consider Similar Space for Sale. We found 7 Spaces matching your search parameters.

$450,000

1,786 SF

Move-In Ready Medical Office Building

Move-in ready medical office with exam rooms, ADA-accessible restrooms, and on-site parking near Advent Hospital.

800 N STONE STREET, Deland, FL 32720

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$425,000

1,750 SF

Turnkey Medical Office Condo

Built in 2011 and ADA-compliant, this turnkey condo includes reception, offices, and exam rooms in a four-unit medical plaza.

844 N Stone Street, Deland, FL 32720

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$450,000

Medical Office Building with Parking

Move-in ready medical building features multiple exam rooms, ADA-accessible restrooms, and dedicated parking.

800 N STONE St, Deland, FL 32720

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$450,000

1,976 SF

Move-In Ready Medical Office Building

Medical office building near Advent Hospital with exam rooms, ADA-accessible bathrooms, and on-site parking.

800 N Stone Street, Deland, FL 32720

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$420,000

4,248 SF

Stand Alone Building in Deland

4,248 SF building with C-2 zoning in Deland, FL.

105 W Calvin St, Deland, FL 32720

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$1,900,000

1.64 Acres

Outparcel For Sale Near Walmart

2.75 AC outparcel with high visibility and traffic.

1702 N Woodland Blvd, Deland, FL

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$449,000

1,750 SF

DeLand Office Condo For Sale

Office condo near Advent Health Deland Hospital with ample parking.

844 N STONE STREET 206, Deland, FL 32720

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

$8,500/Mo

23,056 SF

WINTER PARK Land Lease Opportunity

Commercial land lease opportunity in Winter Park, Florida.

5589 LAKE HOWELL ROAD, Winter Park, FL 32792

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$7,500/Mo

Prime Commercial Lot For Rent

0.66 acre commercial lot with high visibility.

Tift Avenue N, Tifton, GA 31794

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Contact for pricing

Prime Development Opportunity in Greenville

1.27 acre interstate-visible land for ground lease or build-to-suit.

39 Airpark Ct, Greenville, SC 29607

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$5,000/Mo

1,875 SF

Corner Lot on Highway 72

1.7 acre corner lot zoned for commercial, medical, residential.

30472 Highway 72, Madison, AL 35756

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Deland, FL Medical Office Space Market Trends and Statistics

Explore Medical Office Space leasing options in Deland, FL with 3 listings featured on our commercial real estate exchange. The current inventory includes 22,895 square feet of properties with an estimated lease value of $74 SF/Yr.

Estimated lease rates for Medical Office Space in Deland, FL begin at $23 SF/Yr, with an average of $24 SF/Yr and extend to $25 SF/Yr.