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    Palmdale, CA Medical Offices for Lease

    7 results
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    New Medical Office Space
    $2 SF/Yr
    10,000 SF

    New Medical Office Space

    635 Commerce Ave, Palmdale, CA 93551

    Medical office space for lease in Palmdale, California.

    • Brand new medical office space available for lease.
    • Built in 2024.
    • Central air conditioning.
    • Open parking.
    • Foam roof.
    Updated: Oct 27, 2025
    View details
    Palmdale Office Space Available
    $2 SF/Yr
    1,196 SF

    Palmdale Office Space Available

    1529 E Palmdale Blvd, Palmdale, CA 93550

    Move-in ready office spaces in a prominent Palmdale building.

    • Move‑in ready office spaces with various layouts.
    • Prominent three‑story building in the heart of Palmdale.
    • On‑site maintenance available Monday‑Friday.
    • Well‑maintained multi‑stall restrooms on each floor.
    • Central air conditioning.
    Updated: Mar 27, 2025
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    Palmdale Office Space For Rent
    $3 SF/Yr
    1,235 SF

    Palmdale Office Space For Rent

    Office space in a well-located Palmdale plaza.

    853 Auto Center Dr, Palmdale, CA 93551
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    Move-in Ready Medical Office Space
    $2,900 / Mo
    1,250 SF

    Move-in Ready Medical Office Space

    Medical office space for rent in West Palmdale, California.

    40005 W 10Th St, Palmdale, CA 93551
    View details
    Palmdale Place Commerce Center
    $21 SF/Yr
    34,319 SF

    Palmdale Place Commerce Center

    High-traffic Palmdale retail/office

    2231 Palmdale Blvd, Palmdale, CA 93550
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    West Palmdale Plaza Medical Offices
    Contact for pricing
    27,826 SF

    West Palmdale Plaza Medical Offices

    Palmdale medical suites for lease.

    520 Palmdale Blvd, Palmdale, CA 93551
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    Palmdale Medical Office Complex
    Contact for pricing
    133,351 SF

    Palmdale Medical Office Complex

    Prime Palmdale medical office space available.

    39959 Sierra Hwy, Palmdale, CA 93550
    View details
    Based on your search, we've compiled 13 Potential Opportunities for your consideration. Besides 7 Active listings in Palmdale, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 2 Properties for Sales.

    Explore Medical offices for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Medical Office Suite For Rent
    $2 SF/Yr
    1,500 SF

    Medical Office Suite For Rent

    Second floor medical office suite available for lease.

    43860 10Th St, Lancaster, CA 93534
    View details
    10th Street Commerce Center, Lancaster, CA
    $15 SF/Yr
    16,415 SF

    10th Street Commerce Center, Lancaster, CA

    Lancaster Office/Retail Space Available

    44276 10Th St, Lancaster, CA 93534
    View details
    Santa Clarita Office Condo for Lease
    $19 SF/Yr
    2,153 SF

    Santa Clarita Office Condo for Lease

    Prime Medical/Office Space Available

    26330 Diamond Pl, Santa Clarita, CA 91350
    View details
    Santa Clarita Medical Office Space
    $34 SF/Yr
    36,412 SF

    Santa Clarita Medical Office Space

    Prime Medical Office Suites Available

    23501 Cinema Dr, Santa Clarita, CA 91355
    View details

    Explore Similar Spaces for Sale in Palmdale, CA

    Consider Similar Space for Sale. We found 2 Spaces in Nearby Locations matching your search parameters.

    Palmdale Office Building For Sale
    Contact for pricing
    5,518 SF

    Palmdale Office Building For Sale

    5,518 SF Office, Excellent Location

    921 Palmdale Blvd, Palmdale, CA 93550
    View details
    Challenger Business Park: Palmdale Investment
    $9,200,000
    25,306 SF

    Challenger Business Park: Palmdale Investment

    Mixed-use medical & retail investment. High NOI.

    450 Palmdale Blvd, Palmdale, CA 93551
    View details

    Palmdale, CA Medical offices Leasing Opportunities Market Analysis

    Explore Medical offices leasing options in Palmdale, CA with 9 listings featured on our commercial real estate exchange. The current inventory includes 2,090,880,000 square feet of properties with an estimated lease value of $33 SF/Yr.

    Estimated lease rates for Medical offices in Palmdale, CA begin at $2 SF/Yr, with an average of $6 SF/Yr and extend to $21 SF/Yr.
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    Browse Medical offices for Lease Near Palmdale, CA

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    Most Searched ZIP Codes in Palmdale, CA

    • 93551
    • 93550

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