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    Shelby County, AL Medical Office Space for Lease

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    Mobile, AL Birmingham, AL Huntsville, AL
    23 results
    Class A Office Building For Sale
    $19 SF/Yr
    148,877 SF

    Class A Office Building For Sale

    40 Inverness Center Drive, Birmingham, AL 35242

    Renovated Class A office building in a prime location.

    • Highly coveted location in the Highway 280 corridor, at the heart of the I‑459 & US Hwy. 280 market.
    • Newly renovated Class A office building with build‑to‑suit suites available from 1,000 SF - 22,500 SF.
    • Amenity‑rich area with high‑end retail, service retail, banking, day‑care, and restaurants.
    • Full gym and wellness center on‑site.
    • Lush natural setting with views of Memorial Lake, outdoor seating, and walking trails.
    Updated: Nov 21, 2025
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    Beacon Ridge Tower Office Space
    $16 SF/Yr
    153,000 SF

    Beacon Ridge Tower Office Space

    600 Beacon Parkway, Birmingham, AL 35209

    Office and medical suites available near downtown Birmingham.

    • Exceptional value with aggressive full‑service rental rates and ready‑made suites.
    • Spectacular views from Red Mountain with panoramic views of Downtown and Homewood.
    • Convenient location less than 10 minutes to downtown Birmingham and the UAB campus, with easy access to I‑65 and U.S. Hwy. 280.
    • Free surface and covered parking.
    • Suites available from 800+/- SF - 16,964 SF (full floor).
    Updated: Nov 21, 2025
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    Medical/Fitness Space Near Brookwood
    Contact for pricing
    28,000 SF

    Medical/Fitness Space Near Brookwood

    Medical and fitness spaces available near Brookwood Medical Center.

    1651 Independence Ct, Birmingham, AL 35216
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    Medical Office on Hospital Campus
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    102,094 SF

    Medical Office on Hospital Campus

    Medical office building with direct access to Princeton Baptist Medical

    832 Princeton Avenue Southwest, Birmingham, AL 35211
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    Versatile Space in Pelham, AL
    $15 SF/Yr

    Versatile Space in Pelham, AL

    Adaptable commercial space suitable for office, retail, or medical use.

    201 Yeager Parkway, Pelham, AL 35124
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    Medical Office Building For Lease
    Contact for pricing
    54,257 SF

    Medical Office Building For Lease

    Three-story medical office building with space available for lease.

    1004 1st Street N., Alabaster, AL 35007
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    Office Space Near Highway 31
    Contact for pricing
    14,547 SF

    Office Space Near Highway 31

    Office spaces available for lease near Highway 31.

    1022 1st Street N., Alabaster, AL 35007
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    Medical Office Space For Lease
    $19 SF/Yr

    Medical Office Space For Lease

    Medical office building with ample parking and signage opportunities.

    2820 Columbiana Road, Vestavia, AL 35216
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    Medical Office Space Available
    $24 SF/Yr

    Medical Office Space Available

    Medical office space near Shelby Baptist Medical Center, move-in ready.

    1022 1st Street North, Suite 300, Alabaster, AL 35007
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    Midtown/UAB Medical District Location
    Contact for pricing

    Midtown/UAB Medical District Location

    Located in a parking deck with convenient customer parking.

    2021 3rd Avenue South, Birmingham, AL 35233
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    Prime Retail/Medical Space in Chelsea
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    5,921 SF

    Prime Retail/Medical Space in Chelsea

    Move-in ready 2,300 SF space in a high-traffic location.

    361 Chelsea Crossroads, Chelsea, AL 35043
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    Lakeshore Parkway Move-In Ready Property
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    Lakeshore Parkway Move-In Ready Property

    Move-in ready property suitable for office or medical use.

    600 Lakeshore Pkwy, Birmingham, AL 35209
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    Vestavia City Center Office Space
    $18 SF/Yr
    2,760 SF

    Vestavia City Center Office Space

    Office/medical space in mixed-use shopping center, Vestavia Hills, AL.

    700 Montgomery Hwy, Vestavia Hills, AL
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    Medical Mile Commercial Space
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    Medical Mile Commercial Space

    Thriving healthcare and commerce hub in Alabaster's Medical Mile.

    224 1st St N, Alabaster, AL 35007
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    Office Space with High Visibility
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    Office Space with High Visibility

    Office space available with excellent signage, access, and parking.

    1201 2nd Avenue South, Birmingham, AL 35233
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    Premier Medical Location on Highway 280
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    Premier Medical Location on Highway 280

    Premier medical location with customizable build-out packages available.

    5406 US-280, Birmingham, AL 35242
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    Vestavia Hills Office/Medical Space
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    Vestavia Hills Office/Medical Space

    Office/medical space in a high-demographic, mixed-use shopping center.

    700 Montgomery Hwy, Vestavia Hills, AL 35216
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    Medical Office Space for Rent
    Contact for pricing

    Medical Office Space for Rent

    Medical office space with easy access and ample parking.

    52 Medical Park Dr E, Birmingham, AL 35235
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    Medical Office Space in Birmingham
    Contact for pricing

    Medical Office Space in Birmingham

    Medical office suites available on Princeton Baptist Medical Center campus.

    817 Princeton Ave SW, Birmingham, AL 35211
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    Retail and Medical Suites Available
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    3,666 SF

    Retail and Medical Suites Available

    Retail and medical suites available off Hwy 280 in Inverness.

    5291 Valleydale Rd, Birmingham, AL 35242
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    Medical Office Space in Birmingham
    Contact for pricing

    Medical Office Space in Birmingham

    Medical office suites available on Princeton Baptist Medical Center campus.

    833 Princeton Ave SW, Birmingham, AL 35211
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    Medical Office Space in Birmingham
    Contact for pricing

    Medical Office Space in Birmingham

    Medical office suites available on Princeton Baptist Medical Center campus.

    801 Princeton Ave SW, Birmingham, AL 35211
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    Medical Office Space Near Hospital
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    Medical Office Space Near Hospital

    Medical office space directly across from Baptist Shelby Medical Center.

    122 7th Ave NE, Alabaster, AL 35007
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    Based on your search, we've compiled 49 Potential Opportunities for your consideration. Besides 23 Active listings in Shelby County, AL, we suggest exploring alternatives. Similar 26 Properties for Sales.

    Similar Spaces for Sale in Shelby County, AL

    Consider Similar Space for Sale. We found 26 Spaces matching your search parameters.

    Updated Office Suite For Sale
    Contact for pricing
    0.49 Acres
    Updated Office Suite For Sale

    Versatile 1,100 SF suite ideal for various businesses.

    524 RED LANE ROAD, Birmingham, AL 35215

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    Shelby County, AL Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Shelby County, AL with 23 listings featured on our commercial real estate exchange. The current inventory includes 304,637 square feet of properties with an estimated lease value of $53 SF/Yr.

    Estimated lease rates for Medical Office Space in Shelby County, AL begin at $16 SF/Yr, with an average of $17 SF/Yr and extend to $19 SF/Yr.
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