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    Florence, MS Commercial Real Estate for Lease

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    Retail Building on Highway 49
    $6,000 / Mo
    6,000 SF

    Retail Building on Highway 49

    2851 Us 49, Florence, MS 39073

    Freestanding retail building with high visibility in Florence, Mississippi.

    • High‑traffic location with excellent visibility on Highway 49 (31,000+ vehicles per day).
    • Freestanding 6000 sq ft open clear span retail space.
    • Ample parking and accessibility.
    • Located in a growing area with shopping, dining, and recreational amenities.
    • Contemporary design with highly customizable interior.
    Updated: Aug 19, 2025
    View details
    Florence Flex Space For Lease
    Contact for pricing
    15,000 SF

    Florence Flex Space For Lease

    127 Cross Park Dr, Florence, MS

    Flex space with warehouse and lay down yard available for lease.

    • Large 11,500sf warehouse space available.
    • Includes 3,500sf of office space.
    • Benefit from a generous 3.5 acre lay down yard.
    • Dual access for ease of operations.
    • Flex space available for lease.
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    Florence Retail Center - Highway 49
    $10 SF/Yr
    6,000 SF

    Florence Retail Center - Highway 49

    Prime Retail Space, Multiple Units Available

    2785 Us 49, Florence, MS 39073
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    Based on your search, we've compiled 40 Potential Opportunities for your consideration. Besides 3 Active listings in Florence, MS, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 33 Properties for Sales.

    Explore Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Richland Retail Space - Highway 49
    $21 SF/Yr
    1,628 SF

    Richland Retail Space - Highway 49

    High-visibility retail space, 1628 sq ft.

    1055 Highway 49, Richland, MS 39218
    View details
    Richland MS Retail Endcap Suite
    $27 SF/Yr
    6,900 SF

    Richland MS Retail Endcap Suite

    High-traffic retail space available.

    890 Us 49, Richland, MS 39218
    View details
    Pearl, MS Industrial Warehouse
    $5 SF/Yr
    175,000 SF

    Pearl, MS Industrial Warehouse

    175,000 SF Warehouse Space Available

    1125 Weems St, Pearl, MS 39208
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    Rankin County Industrial Space
    $5 SF/Yr
    175,000 SF

    Rankin County Industrial Space

    175,000 SF Warehouse, Refrigerated Space Available

    1125 Weems St, Pearl, MS 39208
    View details

    Explore Similar Spaces for Sale in Florence, MS

    Consider Similar Space for Sale. We found 33 Spaces in Nearby Locations matching your search parameters.

    Spacious Multipurpose Building in Star
    $415,000
    7,972 SF

    Spacious Multipurpose Building in Star

    Versatile 7,972 sqft building ideal for daycare or community initiatives.

    154 Dixie Dr, Florence, MS 39073
    View details
    Prime Commercial Land in Florence
    $589,000
    1.83 Acres

    Prime Commercial Land in Florence

    1.83-acre corner parcel with high visibility and accessibility.

    118 Cross Park Dr, Florence, MS 39073
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    Industrial Building with Office Space
    $495,000
    11,320 SF

    Industrial Building with Office Space

    Industrial building with offices, storage, and yard space for sale.

    778 N Church St, Florence, MS 39073
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    Undeveloped Commercial Lot on Highway
    $495,000
    7.95 Acres

    Undeveloped Commercial Lot on Highway

    7.95 acre commercial lot with highway frontage in Florence, MS.

    Florence Dr, Florence, MS 39073
    View details
    Highway Frontage Commercial Land
    $95,000
    0.66 Acres

    Highway Frontage Commercial Land

    Prime commercial land with high visibility on Highway 49.

    3193 S 49 Pl, Florence, MS 39073
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    Commercial Land on Highway 49
    $800,000
    1.44 Acres

    Commercial Land on Highway 49

    Prime corner lot with high visibility on Highway 49.

    1114 Gunter Rd, Florence, MS 39073
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    Commercial Land in Florence, MS
    $375,000
    0.87 Acres

    Commercial Land in Florence, MS

    Commercial land suitable for business or residential use.

    1118 Gunter Rd, Florence, MS 39073
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    Corner Lot on Highway 49
    $1,175,000
    2.17 Acres

    Corner Lot on Highway 49

    Prime commercial land with high visibility and traffic flow.

    1110 Gunter Rd, Florence, MS 39073
    View details
    29 Acre Commercial Site
    $1,894,872
    29.00 Acres

    29 Acre Commercial Site

    High visibility commercial land on Highway 49 in Florence, MS.

    Highway 49, Florence, MS 39073
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    Highway 49 Commercial Land Opportunity
    $575,000
    4 SF

    Highway 49 Commercial Land Opportunity

    Highly visible commercial land on Highway 49 in Florence, MS.

    2105 S 49 Pl, Florence, MS 39073
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    Undeveloped Commercial Lot in Florence
    Contact for pricing

    Undeveloped Commercial Lot in Florence

    7.95 acre commercial lot with highway frontage in Florence, MS.

    Florence Dr, Florence, MS 39073
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    Highway Frontage Commercial Land
    Contact for pricing

    Highway Frontage Commercial Land

    Commercial land with high traffic visibility on Highway 49.

    3327 Us 49 S, Florence, MS
    View details
    Industrial Facility on 2 Acres
    Contact for pricing

    Industrial Facility on 2 Acres

    Versatile industrial facility with multiple buildings and high ceilings.

    199 S Rankin Industrial Dr, Florence, MS 39073
    View details
    High-Visibility Florence Commercial Lot
    $800,000
    62,726 SF

    High-Visibility Florence Commercial Lot

    Prime corner lot, high traffic, Hwy 49.

    1114 Gunter Rd, Florence, MS 39073
    View details
    High-Visibility Florence Commercial Land
    $399,000
    187,308 SF

    High-Visibility Florence Commercial Land

    4.3 Acres, Hwy 49 Frontage, C3 Zoning

    00 Highway 49, Florence, MS 39073
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    Prime Florence Commercial Land
    $599,000
    79,715 SF

    Prime Florence Commercial Land

    High-traffic corner lot, endless potential.

    118 Crosspark Dr, Florence, MS 39073
    View details
    Florence, MS Multipurpose Building
    $415,000
    7,972 SF

    Florence, MS Multipurpose Building

    Spacious 8,000 sq ft building, ideal for daycare.

    154 Dixie Dr, Florence, MS 39073
    View details
    High-Visibility Florence Commercial Lot
    $1,200,000
    100,567 SF

    High-Visibility Florence Commercial Lot

    Prime corner lot, high traffic, Hwy 49 exposure.

    1110 Gunter Rd, Florence, MS 39073
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    US 49 Industrial Land
    $550,000
    14.97 Acres

    US 49 Industrial Land

    Prime Florence, MS industrial site.

    1764 Us 49, Florence, MS 39073
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    Hwy 49 Commercial Lot, Florence, MS
    $784,080
    1.50 Acres

    Hwy 49 Commercial Lot, Florence, MS

    High-traffic commercial lot, excellent visibility.

    9 Revelation Dr Unit Lot, Florence, MS 39073
    View details
    Hwy 49 Commercial Lot, Florence, MS
    $740,520
    1.00 Acre

    Hwy 49 Commercial Lot, Florence, MS

    High-traffic commercial lot, prime location.

    2 Unit Lot, Florence, MS 39073
    View details

    Florence, MS Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Florence, MS with 36 listings featured on our commercial real estate exchange. The current inventory includes 522,720,000 square feet of properties with an estimated lease value of $22 SF/Yr.

    Estimated lease rates for Commercial real estate in Florence, MS begin at $10 SF/Yr, with an average of $11 SF/Yr and extend to $12 SF/Yr.
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